Experiments with transdermal hormones
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@metabolicmilk What would be the purpose for trying something like Tren in the first place? It's a pretty destructive substance that has essentially no health benefits to it. The only people who need to consider Tren are people trying to get as big as possible, and even most of them know you're playing with fire when you take that shit. I mean, it's your body. I don't care if people smoke crystal meth, I'm just genuinely curious how we go from "fixing the metabolism" to trenbolognia sandwiches.
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@Mulloch94 said in Experiments with transdermal hormones:
@metabolicmilk What would be the purpose for trying something like Tren in the first place? It's a pretty destructive substance that has essentially no health benefits to it. The only people who need to consider Tren are people trying to get as big as possible, and even most of them know you're playing with fire when you take that shit. I mean, it's your body. I don't care if people smoke crystal meth, I'm just genuinely curious how we go from "fixing the metabolism" to trenbolognia sandwiches.
Well the thread name is "experiments with transdermal hormones". You could call tren a hormone.
Back when it was legal there was a US-based company that made a tren PH in both a non-methylated oral form and a transdermal. They had some fancy oral / transdermal tech for good absorption and to avoid needing the methyl group. Would be good to see if that tech could be rejuvenated and applied to other hormones. I had a friend who tried the oral tren PH and the only side effects were higher BP and getting huge.
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@Crypt-Keeper Sounds interesting, I guess your boy is a lucky one. To only get a higher BP and nothing else is a modest reaction to be honest. Some people literally go crazy on the shit. Aggression, anxiety, insomina, even lactation. It's the most neurotoxin steroid out of all the anabolics. Of course, one can't deny the physical results people get from it. I however don't understand this logic of a solo tren cycle. People far more knowledgeable than I on the steroid topic has said a tren cycle should always be accompanied with test. That is if you want your dick to continue to work, lol.
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@metabolicmilk said in Experiments with transdermal hormones:
@Santosh Have you ever experimented with tren base topically?
Yes ! With tren base and Mtren in DMSO.
Completely cured my anhedonia and conditional fear I had developed abusing MK-677 in the past.
They are truly a miracle.I did 3 cycles of two weeks high dose of both.
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@Mulloch94 said in Experiments with transdermal hormones:
@metabolicmilk What would be the purpose for trying something like Tren in the first place? It's a pretty destructive substance that has essentially no health benefits to it. The only people who need to consider Tren are people trying to get as big as possible, and even most of them know you're playing with fire when you take that shit. I mean, it's your body. I don't care if people smoke crystal meth, I'm just genuinely curious how we go from "fixing the metabolism" to trenbolognia sandwiches.
Read my post above.
Stop thinking you may know anything about a hormone in particular just because you read forums. -
@Santosh Do you not think all the accounts people have of themselves (or family members) going crazy and literally threatening to harm themselves or others when taking tren isn't proof enough of it's toxic effects?
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@Mulloch94 said in Experiments with transdermal hormones:
@Santosh Do you not think all the accounts people have of themselves (or family members) going crazy and literally threatening to harm themselves or others when taking tren isn't proof enough of it's toxic effects?
You know these people personnally ?
Anybody can write anything on the internet, including me.
That's why you need to try these things for yourself. -
@Santosh What's the significance of knowing them personally? Last time I checked there isn't some grand conspiracy against trenbolone. It's a substance that serves a particular purpose, and like anything, can have adverse reactions. Also 3 two week cycles isn't that much. I'm sure most people can get away with that before it becomes a huge issue. The typical tren cycle is like 10-12 weeks.
Also you're acting like the only knock on tren thus far is personal anecdotes on forums. We know from research it can elevate prolactin and downregulate serotonin autoreceptors (which isn't good). This supports some of the notable cardio effects users talk about on those forums, like tachycardia and, in extreme cases, heart failure.
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@Mulloch94 said in Experiments with transdermal hormones:
@Santosh What's the significance of knowing them personally? Last time I checked there isn't some grand conspiracy against trenbolone. It's a substance that serves a particular purpose, and like anything, can have adverse reactions. Also 3 two week cycles isn't that much. I'm sure most people can get away with that before it becomes a huge issue. The typical tren cycle is like 10-12 weeks.
Also you're acting like the only knock on tren thus far is personal anecdotes on forums. We know from research it can elevate prolactin and downregulate serotonin autoreceptors (which isn't good). This supports some of the notable cardio effects users talk about on those forums, like tachycardia and, in extreme cases, heart failure.
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Completely reversing anhedonia only took 3x2 weeks.
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You agree that this length of time is not enough to give any harmful effect.
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Why do you keep preaching the harmfulness of these drugs then ?
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@Santosh What is the mechanism of tren fixing anhedonia? I might have to give this a try, although I think mine might be more related to low E2.
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@Crypt-Keeper said in Experiments with transdermal hormones:
@Santosh What is the mechanism of tren fixing anhedonia? I might have to give this a try, although I think mine might be more related to low E2.
Strong androgen receptor agonism that finally wakes up the dormant receptors that haven't been used at all your whole life.
Look at how you and your generation looks like : soft cheeks, soft skin, frail looking without much muscle, thin neck, no energy.
Look at how men who were born in the 50s look like : thick leathery oily skin with strong beards, thick necks, broad shoulders, natural muscle mass without working out, very strong will and never back down when a fight comes up.
That means your receptors haven't worked much since the day you were born because of EDCs, the medications your mother took when she was pregnant, the soft way of life with computers you live.
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@Santosh said in Experiments with transdermal hormones:
What specific points make you think I do ?
Elaborate, don't just throw sarcastic questions especially while hypocritically prefacing they are genuine.
Why would I elaborate when you won't read it anyways? That's the point.
I'm not hypocritical, though. If you answer genuinely, I will too. Not everyone's like you
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@brightside said in Experiments with transdermal hormones:
@Santosh said in Experiments with transdermal hormones:
What specific points make you think I do ?
Elaborate, don't just throw sarcastic questions especially while hypocritically prefacing they are genuine.
Why would I elaborate when you won't read it anyways? That's the point.
I'm not hypocritical, though. If you answer genuinely, I will too. Not everyone's like you
Prefacing a question with the word "genuinely" while making this question rethorical and sarcastic is, indeed, hypocritical.
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@Santosh This is interesting. Thanks for sharing your experience! Do you mind sharing your protocol/dosing? Also why only 2 weeks and how long inbetween did you wait before starting your next 2 weeks?
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Where are people getting 96% ethanol? Is this another thing that's impossible to get in the US because it has stupid laws?
Also, is there a concern about soap residue on the skin being absorbed by DMSO application?
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@Crypt-Keeper
it's available in alberta canada -
@thyroidchor27 Ray say the average healthy male produces around 7mgs a day of testosterone. To be safe, 7mgs shouldn't shut down the gonadal axis.
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I finally got around to trying T in DMSO. Maybe 100 mg T per 1 ml DMSO was too concentrated because there were some crystals left over after application. No white residue or powder, but definitely some kind of tiny glitter on my skin that was only visible in bright light.
I tried 25mg, 100mg and 200mg applications and felt absolutely nothing different. Absolutely nothing. Like as if I smeared water on my skin (other than the DMSO burn).
This is about what I expected though. Some would be tempted to say that my powder is bunk, and maybe it is. But it confirms my suspicion that those who "feel" something from these hormones are either working with placebo, or have low testosterone to begin with. Mood, energy, strength -- nothing. Probably once you're in the high-normal range for T, blasting into the stratosphere doesn't do much more for you.
I think I will run this bottle out with 5-15mg applications once or twice a day just to help keep T in the upper range.
DMSO is awful to work with. Completely impractical for a regular basis. I'll try the (95%) ethanol formulas next.
It would be good if there was a way to pre-treat the skin with some kind of 5-ar inhibitor like topical finasteride to prevent DHT conversion. But then DMSO would bring that in and make it systemic, which you wouldn't want.
Overall I would say that I'm completely unimpressed. But microdosing T with a non-DMSO formula over the long haul might be helpful for gym purposes at least.
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@Crypt-Keeper said in Experiments with transdermal hormones:
I finally got around to trying T in DMSO. Maybe 100 mg T per 1 ml DMSO was too concentrated because there were some crystals left over after application. No white residue or powder, but definitely some kind of tiny glitter on my skin that was only visible in bright light.
I tried 25mg, 100mg and 200mg applications and felt absolutely nothing different. Absolutely nothing. Like as if I smeared water on my skin (other than the DMSO burn).
This is about what I expected though. Some would be tempted to say that my powder is bunk, and maybe it is. But it confirms my suspicion that those who "feel" something from these hormones are either working with placebo, or have low testosterone to begin with. Mood, energy, strength -- nothing. Probably once you're in the high-normal range for T, blasting into the stratosphere doesn't do much more for you.
I think I will run this bottle out with 5-15mg applications once or twice a day just to help keep T in the upper range.
DMSO is awful to work with. Completely impractical for a regular basis. I'll try the (95%) ethanol formulas next.
It would be good if there was a way to pre-treat the skin with some kind of 5-ar inhibitor like topical finasteride to prevent DHT conversion. But then DMSO would bring that in and make it systemic, which you wouldn't want.
Overall I would say that I'm completely unimpressed. But microdosing T with a non-DMSO formula over the long haul might be helpful for gym purposes at least.
Your powder is bunk, indeed.
There is nothing placebo about the testosterone base surge you feel in DMSO, especially when you use 100mg or more at a time.Those who have tried it know.
Those who wish they tried it scream placebo. -
@Santosh said in Experiments with transdermal hormones:
Your powder is bunk, indeed.
I guess I will send it off to Janoshik since it's probably important to know what I'm taking into my body with DMSO.
I found it strange that PPL had a message on their website saying not to test with Janoshik and anyone who posted results from them on a forum would be banned from buying again.
Guess I'll look elsewhere for raws.
