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Experiments with transdermal hormones

Bioenergetics Discussion
testosterone transdermal trt hormones
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  • C
    Crypt Keeper @wester130
    last edited by Jun 23, 2024, 5:59 PM

    @wester130 Interesting. Mine tastes incredibly bitter, similar to extra-virgin olive oil.

    W 1 Reply Last reply Jun 23, 2024, 7:52 PM Reply Quote 0
    • W
      wester130 @Crypt Keeper
      last edited by Jun 23, 2024, 7:52 PM

      @Crypt-Keeper is it base powder? does it cause brain fog?

      Personally I am going to try testosterone gel and see if I get the chemical feeling

      C 1 Reply Last reply Jun 23, 2024, 7:59 PM Reply Quote 0
      • C
        Crypt Keeper @wester130
        last edited by Jun 23, 2024, 7:59 PM

        @wester130 It's supposed to be base powder. I don't experience any brain fog even in high doses. I actually don't experience anything noticeable.

        W 1 Reply Last reply Jun 25, 2024, 4:35 PM Reply Quote 0
        • W
          wester130 @Crypt Keeper
          last edited by Jun 25, 2024, 4:35 PM

          @Crypt-Keeper have you consdiered making your own T gel?

          it's basically isopropyl myristate, ever and T

          maybe add in vitamin E?

          C 1 Reply Last reply Jun 25, 2024, 6:42 PM Reply Quote 0
          • C
            Crypt Keeper @wester130
            last edited by Jun 25, 2024, 6:42 PM

            @wester130 I have some IPM and MCT oil, just need to get some Everclear. I think the most I can get is 95% alcohol. I would like to experiment with that, but I figure if DMSO didn't give me any perceptible effects, Everclear and IPM might not be worth it.

            I am thinking of trying to source some dutasteride and give that a try with the T. I don't want the DHT conversion that oral / transdermal gives.

            W 1 Reply Last reply Jun 25, 2024, 8:12 PM Reply Quote 0
            • W
              wester130 @Crypt Keeper
              last edited by Jun 25, 2024, 8:12 PM

              @Crypt-Keeper are you joking?? dutasteride?

              DMSO is dangerous anyway and does not necessarily increase absorption

              IPM increases absorption by 11 times,

              1 Reply Last reply Reply Quote 0
              • P
                pannacottas
                last edited by Jul 10, 2024, 8:19 AM

                So for the past month ive been experimenting with figuring out the maximum solubility of DHT in ethanol. For me DMSO is not an option for me so ethanol is the next best thing.

                Using 99% undenatured ethanol, i was able to achieve up to 70mg/ml. 75mg/ml did not dissolve, twice.
                With the 70gm/ml solution i tried 2%, 5% and 10% IPM, and a mix of IPM and tocopherol of 5% total, each being around 2.5%, which brings the total concentration down to 50-53mg/ml.

                The best by far is the tocopherol and IPM mixture. Leaves minimal to non existent powder line after it dries, has the slowest evaporation of all and is very pleasant to the skin. The IPM only solutions, especially the 2% leaves a very noticeable trace line of powder at the edges of where the liquid was applied, after evaporating.

                The only caveats regarding the max solubility is that my ethanol measurement wasnt accurate enough and was maybe off by +- 1-2ml. I used a kitchen scale to measure the equivalent weight in grams and then poured it into a beaker which confirmed the total volume, but none was super accurate so ill try again with a more accurate measuring tool like a pipette.

                However im fairly confident that 100mg/ml is not achievable, and i know for a fact 200mg/ml is not. Im saying this because theres someone on the black market selling 10% and 20% DHT gel, and he offers a non DMSO option which he uses ethanol for. I dont know the max solubility of DHT in DMSO, but if you got any of the non DMSO gels, you probably got scammed.

                W 1 Reply Last reply Jul 10, 2024, 7:02 PM Reply Quote 0
                • W
                  wester130 @pannacottas
                  last edited by Jul 10, 2024, 7:02 PM

                  @pannacottas what effects are you noticing?

                  From my understanding - DHT basically does nothing. It's testosterone that gives the effect

                  P W 2 Replies Last reply Jul 10, 2024, 8:06 PM Reply Quote 0
                  • P
                    pannacottas @wester130
                    last edited by Jul 10, 2024, 8:06 PM

                    @wester130 With DHT you dont "feel" anything immediate, it is afterwards that you notice things like improved cognition, calmness, decrease in libido, ability to think clearly, decreased aggression, more outgoing, and generally ape mode, in the sense that you dgaf and eg. can overtake cars easily (Landshark talked about this). At least thats my experience with it

                    Imo most, if not all of the benefits of T are from the conversion to DHT. The reason that ppl feel T when taking it, is likely from some aromatization thats happening which causes a mild excitatory effect, but is accompanied with T and DHT so it's balanced. DHT lacks that effect as it's non-aromatizable.

                    W 1 Reply Last reply Oct 20, 2024, 8:43 PM Reply Quote 0
                    • M
                      milkgains_bro
                      last edited by Jul 11, 2024, 9:40 AM

                      @wester130 With DHT in DMSO my estrogen gets to very low levels, so my libido, mood etc is tanked. I did not liked it at all. Transdermal test is much better since its boost test, estrogen and DHT all at once.

                      1 Reply Last reply Reply Quote 0
                      • W wester130 referenced this topic on Jul 16, 2024, 5:50 PM
                      • W
                        wester130 @wester130
                        last edited by wester130 Jul 26, 2024, 1:38 PM Jul 26, 2024, 1:35 PM

                        @wester130

                        fascinating article about dht

                        should we take this instead?

                        http://www.treatprostatitis.com/causes-of-prostatitis/

                        https://books.google.co.uk/books?id=ImEoDwAAQBAJ&pg=PT85&lpg=PT85&dq="dht+supplementation"&source=bl&ots=OPqZpMrkIf&sig=ACfU3U0Rkb-f-Z7Hf2Ww_nZwWt_AZ_zM5A&hl=en&sa=X&ved=2ahUKEwiihO2Yj8CHAxVWQkEAHfnuJxY4ChDoAXoECCIQAw#v=onepage&q="dht supplementation"&f=false

                        1 Reply Last reply Reply Quote 0
                        • W
                          wester130 @pannacottas
                          last edited by Oct 20, 2024, 8:43 PM

                          @pannacottas thanks

                          1 Reply Last reply Reply Quote 0
                          • M
                            metabolicmilk
                            last edited by Oct 23, 2024, 12:20 AM

                            I have created a solution of

                            25mg Tren
                            25mg Test
                            5mg Progesterone
                            5mg DHEA
                            5mg Exemestane

                            Per ml

                            I used DMSO & Coconut Oil in about a 90:10 ratio. This is mostly to stop the stinging/skin irritation from pure DMSO. They don't mix great so you need to shake before use. I would have preferred to use Vitamin E if I had on hand.

                            It is working great so far. Definitely a lot stronger than my higher T experiments in the past.

                            I have noticed zero sides from the Tren.

                            It has been about 4 weeks

                            W K 3 Replies Last reply Oct 23, 2024, 4:33 PM Reply Quote 0
                            • Y
                              yeyo12
                              last edited by yeyo12 Oct 23, 2024, 10:51 AM Oct 23, 2024, 10:50 AM

                              I have

                              vitamin e tocopherol oil
                              ethyl alcohol
                              base micronized test powder in my hand.

                              can anyone help me with the recipe of how I can make a transdermal cream out of these?

                              should I try to get isopropyl myristate as well?

                              thank you!!

                              M 1 Reply Last reply Oct 23, 2024, 8:03 PM Reply Quote 0
                              • W
                                wester130 @metabolicmilk
                                last edited by Oct 23, 2024, 4:33 PM

                                @metabolicmilk sounds interesting

                                1 Reply Last reply Reply Quote 0
                                • M
                                  metabolicmilk @yeyo12
                                  last edited by Oct 23, 2024, 8:03 PM

                                  @yeyo12 using those ingredients I would do

                                  20% IPM
                                  50% alcohol
                                  30% Vitamin E

                                  Are you opposed to DMSO?

                                  Y 1 Reply Last reply Oct 24, 2024, 10:43 AM Reply Quote 0
                                  • Y
                                    yeyo12 @metabolicmilk
                                    last edited by yeyo12 Oct 24, 2024, 10:43 AM Oct 24, 2024, 10:43 AM

                                    @metabolicmilk

                                    thank you
                                    I have to get some IPM

                                    uhh, I've never really tried DMSO myself, but I've seen a lot of users have problem with it and I don't really want to smell -if it does that-

                                    Does it make you smell like garlic?

                                    M 1 Reply Last reply Oct 25, 2024, 9:12 PM Reply Quote 0
                                    • M
                                      metabolicmilk @yeyo12
                                      last edited by Oct 25, 2024, 9:12 PM

                                      @yeyo12 there was a post on old rpf about how using honey removes the smell. If you want a DMSO formula Id use 70 DMSO : 20 Vit E : 10 honey

                                      1 Reply Last reply Reply Quote 0
                                      • K
                                        Kilgore @metabolicmilk
                                        last edited by Kilgore Oct 25, 2024, 11:59 PM Oct 25, 2024, 11:55 PM

                                        @metabolicmilk
                                        What is your goal with this?

                                        Which testosterone & DHT bases are good for topical application? (fromPPL)

                                        Also whats the Exemestane for?

                                        M 1 Reply Last reply Nov 5, 2024, 4:15 PM Reply Quote 0
                                        • W
                                          wester130 @metabolicmilk
                                          last edited by Oct 31, 2024, 1:30 PM

                                          @metabolicmilk what other results are you getting?

                                          M 1 Reply Last reply Nov 5, 2024, 4:16 PM Reply Quote 0
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