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    5 Substances I would take to treat depression before SSRIs and why

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    • serotoninskepticS
      serotoninskeptic @wrl
      last edited by

      @wrl Yes i was thinking magnesium and
      Coconut water is definitely a great source of protective anti-stress minerals. Maybe glycine or lysine for reducing anxiety also.

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      • ?
        A Former User
        last edited by

        Also worth mentioning how substances can be a cope for depression-inducing lifestyle factors. A person can be stuck in behavioral loops that make them turn to substances (or drugs). I suppose there is a spectrum of expediency when it comes to lifestyle decisions and some are within immediate reach and others are less proximate from starting position. In the latter case, replacement (healthy) substances may be worthy as tentative aids in the course of treatment.

        InsomniacI serotoninskepticS 2 Replies Last reply Reply Quote 0
        • InsomniacI
          Insomniac
          last edited by

          unfortunately I don't see anyone selling phenylpropylaminopentane

          serotoninskepticS 1 Reply Last reply Reply Quote 0
          • InsomniacI
            Insomniac @A Former User
            last edited by

            @jwayne Completely true. Ideally everyone tries a good diet and regular exercise before looking to chemicals and supplements but it's extremely hard to change lifelong habits.

            Often it's ozempic or a diabetic coma even though people can see what's coming.

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            • serotoninskepticS
              serotoninskeptic @A Former User
              last edited by

              @jwayne Yes of course lifestyle and diet changes come first. Finding interesting creative hobbies, stimulating life, staying nourished, getting sunlight/grounding etc. But if one must resort to substances these could be beneficial.

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              • serotoninskepticS
                serotoninskeptic @Insomniac
                last edited by

                @Insomniac I know somebody on twitter who had it. Im not sure his source though I could ask

                InsomniacI 1 Reply Last reply Reply Quote 0
                • JenniferJ
                  Jennifer
                  last edited by Jennifer

                  The 5 substances I had the most success with treating depression are:

                  • Thyroid
                  • Progest-E
                  • Antimicrobials like camphor and oregano oil
                  • Caffeinated black tea or coffee right after a meal
                  • Häagen-Dazs or any ice cream made with egg yolks for extra cholesterol

                  I have stood on a mountain of no’s for one yes. ~ B. Smith

                  serotoninskepticS 1 Reply Last reply Reply Quote 0
                  • InsomniacI
                    Insomniac @serotoninskeptic
                    last edited by

                    @Serotoninskeptic Thanks but there's no need. If I have any anxiety about the purity then I won't keep with it.

                    Selegiline might be a good substitute

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                    • serotoninskepticS
                      serotoninskeptic @Jennifer
                      last edited by

                      @Jennifer Ice Cream needs to be the new norm for depression treatment

                      JenniferJ 1 Reply Last reply Reply Quote 0
                      • JenniferJ
                        Jennifer @serotoninskeptic
                        last edited by Jennifer

                        @Serotoninskeptic, I agree. A treatment and preventative. 👍

                        I have stood on a mountain of no’s for one yes. ~ B. Smith

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                        • AnakinA
                          Anakin
                          last edited by

                          Cypro lowers dopamine nd choline and make u unmotivated

                          But good at lower serotonin

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                          • ?
                            A Former User @serotoninskeptic
                            last edited by A Former User

                            @Serotoninskeptic
                            Thiamine is very important for depression.
                            https://hormonesmatter.com/depression-anxiety-chronically-hypoxic-brain/

                            Thiamine is required to clear serotonin from the brain.
                            Effect of thiamine deficiency on brain serotonin turnover

                            Magnesium is very important too:
                            Magnesium Status and Stress: The Vicious Circle Concept Revisited

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                            • serotoninskepticS serotoninskeptic referenced this topic on
                            • CearrsonC
                              Cearrson
                              last edited by

                              How do you recommend supplementing Cypro
                              I have administered it to my GF with seemingly no effect except it making her drowsy/ groggy the next day. we used georgi's and did 2-4 drops (1-2mg) every two or three nights but only did it two or three times as I saw no noticeable effects, thoughts?

                              serotoninskepticS 1 Reply Last reply Reply Quote 0
                              • serotoninskepticS
                                serotoninskeptic @Cearrson
                                last edited by

                                @Cearrson Yea i wouldnt use it every day. Every 2-3 days seems good. Have you tried a higher dose with georgi's?

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                                • onliestO
                                  onliest @serotoninskeptic
                                  last edited by

                                  @Serotoninskeptic Good list. Taurine, glycine and creatine are also worth mentioning

                                  serotoninskepticS 1 Reply Last reply Reply Quote 0
                                  • serotoninskepticS
                                    serotoninskeptic @onliest
                                    last edited by

                                    @onliest Yes also some good picks. I might make a second list

                                    onliestO 1 Reply Last reply Reply Quote 0
                                    • onliestO
                                      onliest @serotoninskeptic
                                      last edited by

                                      @Serotoninskeptic have you tried allo-p?

                                      serotoninskepticS 1 Reply Last reply Reply Quote 0
                                      • serotoninskepticS
                                        serotoninskeptic @onliest
                                        last edited by serotoninskeptic

                                        @onliest Not personally but ive heard good testimonies

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