Random, interesting studies
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Some studies that I won't make a thread on and analyze them deeply. Yet I still think are noteworthy.
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Caffeine Targets SIRT3 to Enhance SOD2 Activity in Mitochondria
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Sirt3 Deficiency Shortens Life Span and Impairs Cardiac Mitochondrial Function Rescued by Opa1 Gene Transfer
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"SIRT3 reduced the expression of stearoyl-CoA desaturase 1..."
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No study but isn't it interesting that
Guggulsterone (C21H28O2) and
Pregnenolone (C21H32O2) are almost the same molecules.
That explains their similar effects.Z-Guggulsterone alleviates renal fibrosis by mitigating G2/M cycle arrest through Klotho/p53 signaling
https://pubmed.ncbi.nlm.nih.gov/35123992/Dare to think.
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@Mauritio can you explain the similarities?
They seem very different in their structure to me -
@alfredoolivas The backbone is very similar not sure how to explain that to you
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High salt diet induces muscle loss via cortisol, if simultaneously given saline Solution, not if rats were given tap water.Maybe there's a Sweet Spot for Salt.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5409074/Dare to think.
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A sweet spot, a circadian and an infradian. I'll be lucky if I can get there a few times a week because it's a moving target. Unless I do nothing, say nothing, go nowhere and see no one.
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Dates (polyphenols) activate FXR and modulate bile acids.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5749773/ -
Chlorogenic Acid Inhibits Lipid Deposition by Regulating the Enterohepatic FXR-FGF15 Pathway
https://pubmed.ncbi.nlm.nih.gov/35257010/Chlorogenic acid fed mice increase less in weight than controls mice on a high fat diet. AND weigh less than animals on a normal control diet.
https://pubmed.ncbi.nlm.nih.gov/20064576/Might inhibit Mao a+b
https://pubmed.ncbi.nlm.nih.gov/29893510/ -
I like this thread.
Thank you -
@dapose you're welcome.
