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Niclosamide reduces serotonin and glutamate

Literature Review
serotonin niclosamide glutamate
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  • C
    cs3000 @Mauritio
    last edited by cs3000 Feb 24, 2025, 11:07 AM Feb 24, 2025, 11:02 AM

    @Mauritio amazing result . tho in supp materials didnt show much effect for the lung tumor metastasised for some reason
    https://pubmed.ncbi.nlm.nih.gov/27153561/
    (increasing apoptosis with the lowered pH from co2, or reversing hypoxia, then inhibiting proliferation further , but not always,
    are some exceptions like with certain tumors characterized by poor immune cell infiltration, carbonic anhydrase inhibition doesnt help because even less immune infiltration with the lower pH, but a general approach)

    "world," as a source of new perceptions
    more https://substack.com/@cs3001

    "Self-organizing systems decay only if they have assimilated inertia and — with a little support of the right kind— the centers of degeneration can become centers of regeneration"

    1 Reply Last reply Reply Quote 0
    • M
      Mauritio
      last edited by Feb 28, 2025, 6:58 PM

      Niclosamide has excellent safety profile. They gave humans up to 1600mg daily and they observed no major side effects.
      I'm taking about 50mg .

      Dare to think.

      My X:
      x.com/Metabolicmonstr

      C 1 Reply Last reply Feb 28, 2025, 7:17 PM Reply Quote 0
      • C
        cs3000 @Mauritio
        last edited by cs3000 Feb 28, 2025, 7:18 PM Feb 28, 2025, 7:17 PM

        @Mauritio hmm i read a trial where they gave 500mg x3 and had to stop the study because of side effects , but another trial didnt, maybe it was the timeframe not sure but it has some mutagenic effects , those are megadoses tho

        low dose orally took out an antibiotic resistant strain of Enterococcus bacteria in mice https://pmc.ncbi.nlm.nih.gov/articles/PMC5988938/figure/F4/

        "world," as a source of new perceptions
        more https://substack.com/@cs3001

        "Self-organizing systems decay only if they have assimilated inertia and — with a little support of the right kind— the centers of degeneration can become centers of regeneration"

        M 1 Reply Last reply Feb 28, 2025, 7:45 PM Reply Quote 0
        • M
          Mauritio @cs3000
          last edited by Feb 28, 2025, 7:45 PM

          @cs3000 oh what were those side effects ?

          Wow, niclosamide night be able to replace the low infrequent antibiotic dose peat recommend and the dosage wasn't even that high. Nice.

          Dare to think.

          My X:
          x.com/Metabolicmonstr

          B 1 Reply Last reply Feb 28, 2025, 8:51 PM Reply Quote 0
          • B
            bio3nergetic @Mauritio
            last edited by Feb 28, 2025, 8:51 PM

            @Mauritio sorry if I missed it, but where do you get this stuff from?

            M 1 Reply Last reply Feb 28, 2025, 9:00 PM Reply Quote 0
            • M
              Mauritio @bio3nergetic
              last edited by Mauritio Feb 28, 2025, 9:01 PM Feb 28, 2025, 9:00 PM

              @bio3nergetic it's OTC in Germany. You can get 4 500mg pills for like 15€ ,which should be enough to try it out. For me that's like 40 dosages so will last quite a while.
              It's called yomesan.

              Dare to think.

              My X:
              x.com/Metabolicmonstr

              B A M 3 Replies Last reply Feb 28, 2025, 9:22 PM Reply Quote 0
              • B
                bio3nergetic @Mauritio
                last edited by Feb 28, 2025, 9:22 PM

                @Mauritio said in Niclosamide reduces serotonin and glutamate:

                yomesan

                Thanks, I'll look into US options.

                1 Reply Last reply Reply Quote 0
                • A
                  alfredoolivas @Mauritio
                  last edited by alfredoolivas Feb 28, 2025, 9:47 PM Feb 28, 2025, 9:45 PM

                  @Mauritio You have me curious, have you tried this at all? Edit: You have, did you experience any mental benefits?

                  M 1 Reply Last reply Feb 28, 2025, 9:53 PM Reply Quote 0
                  • M
                    Mauritio @Mauritio
                    last edited by Feb 28, 2025, 9:49 PM

                    @Mauritio said in Niclosamide reduces serotonin and glutamate:

                    @bio3nergetic it's OTC in Germany. You can get 4 500mg pills for like 15€ ,which should be enough to try it out. For me that's like 40 dosages so will last quite a while.
                    It's called yomesan.

                    Inflation is real on this one.
                    In 2021: 5 tablets 6€
                    2025: 4 tablets 15€

                    Had to look up my old post on it lol
                    Post in thread 'Niclosamide for fat loss/ uncoupling' https://lowtoxinforum.com/threads/niclosamide-for-fat-loss-uncoupling.42781/post-718904

                    Dare to think.

                    My X:
                    x.com/Metabolicmonstr

                    1 Reply Last reply Reply Quote 0
                    • M
                      Mauritio @alfredoolivas
                      last edited by Feb 28, 2025, 9:53 PM

                      @alfredoolivas yes you can look up my posts on the thread on the rpf on it.
                      And I still experience increased mood and energy on it. Im figuring out the dosage.
                      50mg seemed to be too much . 25 too little and today I took 35mg . Which seems to be a good mix.

                      So 35mg, 1-2/week might be a good protocol.

                      Dare to think.

                      My X:
                      x.com/Metabolicmonstr

                      A 1 Reply Last reply Feb 28, 2025, 11:17 PM Reply Quote 0
                      • A
                        alfredoolivas @Mauritio
                        last edited by Feb 28, 2025, 11:17 PM

                        @Mauritio I can't look stuff up on the RPF anymore due to a pay wall :(. Is there a long half life, therefore it should be only taken a few times a week? What were the "too much" symptoms from the 50mg doses?

                        B 1 Reply Last reply Mar 1, 2025, 2:13 AM Reply Quote 0
                        • B
                          bio3nergetic @alfredoolivas
                          last edited by bio3nergetic Mar 1, 2025, 2:15 AM Mar 1, 2025, 2:13 AM

                          @alfredoolivas Mauritio is referring to this one. I remember I was watching that thread when we were all there.
                          lowtoxinforum DOT com/threads/niclosamide-for-fat-loss-uncoupling.42781/page-6

                          BTW, no worries about his nonsense paywall. Simply using g00gle with a site exclusive search string (at least g00gle turns out to be good for ONE thing!) You can search for anything on that forum using this method.

                          Example: Niclosamide site:raypeatforum.com
                          

                          Yes I also stick it to him by NEVER typing the low toxin blah blah title. That is RAY PEAT'S work he built that forum on. I will always type the old, true name.

                          And yes, I will never post actual inbound links to that forum. Leaving links only helps "his" forum's ranking.

                          A 1 Reply Last reply Mar 1, 2025, 9:06 AM Reply Quote 0
                          • A
                            alfredoolivas @bio3nergetic
                            last edited by Mar 1, 2025, 9:06 AM

                            @bio3nergetic thank you, I think it's okay to share the link. its in the name of science 😉

                            1 Reply Last reply Reply Quote 0
                            • M Mauritio referenced this topic on Apr 26, 2025, 11:16 AM
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