Smelling citrus scent cures depression in 75% of study participants
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Amazing!
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How they created the oil:
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@Mauritio said in Smelling citrus scent cures depression in 75% of study participants:
Coincidentally lemon and orange oil consist of limonene to a large degree
Here's a short list of limonenes benefits:
D-Limonene
🟩:
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Increases brain GABA + lowers serotonin
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Reduces endotoxin and obesity in animal studies
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Increases UCP2
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Anti-viral, anti- bacterial, anti-fungal
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Anti-fibrotic
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Increases bile acids
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Increases vitamin C (up to 15 times in one study)
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Increases Testosterone (slightly) and increases androgen receptor expression
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Has Pregnancy supporting effects
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i sometimes leave lemon and orange peels around
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@sushi_is_cringe same. sometimes I put them on the heater which spreads the scent.
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@Mauritio ,
Notwithstanding a beneficial role of fragrances on nervous and immune, this s study appears a bit weak as the authors point out themselves in the end of the Discussion section:
"In a future study, however, the AD [anti-depressant] group should be controlled by a separate group in which the dose of antidepressants should be halved unless the subjects in the CF [citrus fragrance] group completely discontinue antidepressants simultaneously with the use of citrus fragrance."A problem, as I see it, is that the CF group was given a choice on how they want their dose to be reduced, which not necessarily depended on the assessed depression levels.
Also I could not find in the paper for how long the fragrance was applied. Post-assessments show only the number of weeks after the fragrance application.
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@Lejeboca I assume that these problems with the paper are not due to authors' sloppiness or ineptitude but rather to the restriction in working with human subjects.
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@Lejeboca Indeed, the paper by the subset of these authors seems to me very good:
Immunological and behavioral effects of fragrance in mice"In this study, the stress induced by exposure to high pressure was found to involve thymic involution and reduce PFC [plaque-forming cells] production via the activation of suppressor T cells in mice. The results showed that this response to stress involving thymic involution was blocked by the exposure to fragrance."
"In order to evaluate the behavioral change induced by stress, spontaneous running activity was measured by a photocell counter. Running activity in mice was enhanced by high pressure stress, however, the enhancement of running activity was reduced by exposure to the fragrance (Figure 6)."
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@Mauritio Whenever I go for a walk and see a pine tree or pine shrug, I pick of some of the needles, crush them between my fingers and smell it as I walk.
Probably the same effect.
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Any practical experiments we can run on this subject?
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@Lejeboca said in Smelling citrus scent cures depression in 75% of study participants:
which not necessarily depended on the assessed depression levels.
What else would it depend on? The limiting factor for lowering your AD dose is if youre well enough to handle it. So if their depression didn't get better, they wouldn't have been able to reduce their dosage. As can be seen by the 3 individuals, that weren't well enough to completely come off AD's, so they didn't.
@Lejeboca said in Smelling citrus scent cures depression in 75% of study participants:
Also I could not find in the paper for how long the fragrance was applied. Post-assessments show only the number of weeks after the fragrance application.
It says it took 4-11 weeks to work, that's all I need to know.
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@jamezb46 good point. I love the smell of pine trees, too.
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@Gaston Well how about smelling citrus scent?:D
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I already see Peaters running around with brown paper bags full of orange and lemon peel, which they sniff like people used to do with glue. Positive side effect: You can use the paper bag for bag rebreathing afterwards.
It smells pretty decent though.
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@Mauritio said in Smelling citrus scent cures depression in 75% of study participants:
What else would it depend on?
For example, fear of getting off meds.
@Mauritio said in Smelling citrus scent cures depression in 75% of study participants:
It says it took 4-11 weeks to work, that's all I need to know.
4-11 weeks after the use of fragrance lasting for how long?