Aspirin induced Gastritis?
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@happyhanneke okay great, if this is my issue what would be the best way to flush my system of excess aspirin that could be irritating my stomach? Just eating food? anything that kindof neutralizes the effect?
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@Cearrson
I don't really know that.
I took my colitis medicaton that I had not used in a long long time but I know it works quickly.
It's basically an anti inflammatory, I just take it as a suppository because oral meds have never worked for my colitis. I learned that by living with it for 25+ years.It's asacol (mesalamine) suppository 1000mg.
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Yes, chronic use of aspirin can cause abnormal excess bleeding, which implies that aspirin can have adverse effects on the gastrointestinal tract. Also, it is known that aspirin, being a nonsteroidal anti-inflammatory drug (NSAID), can inhibit prostaglandin synthesis, which can lead to gastrointestinal issues such as gastritis.
@Cearrson said in Aspirin induced Gastritis?:
325mg Bayer Aspirin Tablets
There are alot of inactive ingredients in 5-6 tablets is lot of inactive ingredients. I use aspirin powder dissolved in my moring coffee.
“All things are poison and nothing is without poison; only the dose makes a thing not a poison.” - Paracelsus (c. 1493–1541)
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@DavidPS Damn, I had never looked on their sneaky little hidden panel before. I though Bayer was clean. Time to get some powder I suppose, I'll lay off the aspirin for a bit now however and make sure I take it with food etc.
As I'm eating currently I can feel it keeping the pain at bay. Hopefully I get this Aspirin flushed out of my system and the irritation goes down soon. -
@Cearrson - For me, the coated tablets are the worst. They do not dissolve quickly and I think it makes it more likely that the acid (acetylsalicylic acid) will be localized in your GI track for a longer period of time. For fun, place a tablet in water and wait and see how long it takes to dissolve. Some people dissolve uncoated tablets (held together with binders) this way. They wait until the tablets dissolve and then slowly pour off as much water into another glass. The trick is to avoid pouring the sludge into the second glass.
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The tablet should be dissolved or crushed before taking. Gericare brand I've heard is good because the only additive is corn starch. Ray Peat never took more than 500 mg in one go. He recommended the crystals over the powder and to refrigderate some and freeze the rest for longterm storage. Take 1 mg vitamin k2 per 325 mg aspirin, don't use k1. Lastly, take alongside gelatin and a bit of baking soda. (protects stomach)
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A doctor who wrote a book on copper of which I had forgotten his name, suspects that the reason some people are sensitive to aspirin in the gut, causing gastritis, is that they are low on copper.
If you check your cerrulpplasmin levels, they could be low. If that is indeed the cases, to increase copper stores, it ia better to eat plenty of food that is copper rich than to rely on copper supplementation, as Ray thinks that no one really knows the right dosage for supplementing copper. It's a crapshoot as you wouldn't know where you are undersupplementing or over.
My way of eating copper rich foods had me raising my cerruloplasmin from low of range (22) to high of range (38) with range being from 18-42, in a year's time.
In addition, being sufficient in red light exposure is needed to make the increased copper turn into enzymes such as cytochrome c oxidase.
But what I eat is something the American culture couldn't take except for the adventuresome and trainable palates. I ate a dish of cooked green leaves mixed and cooked with a fermented crustacean sauce called bagoong which can be found in Filipino grocery stores for sure, and perhaps also in Asian stores by other names. Malaysians call it belacan.
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@Cearrson glycine is used in aspirin overload its used in clearing aspirin in the body (glycine conjugation)
if i were you i'd leave the aspirin for now. then in the future would take it with some glycine (500mg, no need for a lot studies showed even less helps to lower gi effects taken simultaneously, and haidut posted something about it maybe increasing potency so less needed),
maybe 1 max is good,
and dispersible form maybe best so large chunks dont stick to one spot in the stomach , i wouldnt take that coated form ever as its damaging to the small intestine which is ironic considering how its advertised (lets call it safe and just shift the damage to the small intestine?)
https://www.cghjournal.org/article/S1542-3565(08)00670-8/fulltext (similar damage with potassium supplements)& for healing if the gastritis (or maybe its duodenum damage which is next to the gallblader and changes pH so if it was enteric coated acid it can start to damage there) , if it doesnt resolve soon naturally after stopping, you could try theanine (high dose isnt better and might reverse to worsening, but might accelerate repair nicely at the lower end optimal dose could be ~50mg-70mg https://link.springer.com/article/10.1007/s11418-014-0852-x
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@cs3000 (weirdly it looks like the glycine added to aspirin doesnt prevent damage in the gut at least, maybe it would elsewhere e.g helping tinnitus, somehow a low glycine dose 250mg potently lowers the pain response with the same damage from aspirin, so alone without other changes probably isnt enough https://www.cochranelibrary.com/central/doi/10.1002/central/CN-00510392/full , probably still happens because of its intended effect on prostaglandins which are needed there or something (pge2 / cox2 involved in gut repair), or taking non dispersible form (dispersible form floats in the stomach liquid more and spaces apart, easier to deal with)
