Diclofenac gel to regrow hair on bald head and beard
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@wester130 I forget the exact time period — maybe 7-10 years ago — there was a time when people were putting Retin-A on their scalps for potential hair growth. Retin-A is just what it sounds like, used by dermatologists to recondition skin. Back when I read about it, to my layman's mind, I assumed the Retin-A was just working similarly to salicylic acid, reconditioning the scalp, which was very popular in the hair loss community for a while; but maybe there was something to the vitamin A itself, not just the resurfacing.
For what it's worth, I feel like food based vitamin A, via liver, is one of the best Peaty things yet for me. I definitively feel noticeably better on it, with no side effects. I've just been thinking about this recently, about attempting to consume more liver for more vitamin A. They say your body craves what it needs.
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@Mossy many companies are mixing Minoxidil with treitinoin, so it is positively affecting the collagen
i am not sure of what mechanism, maybe inflammation, maybe improving collagen,
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I think treitinoin helps absorption, but also:
Chat GPT says:
Tretinoin (a retinoid) increases skin cell turnover and thins the outermost layer of the skin (stratum corneum), which can:
Increase scalp permeability
Allow more minoxidil to reach the folliclesMinoxidil must be converted into minoxidil sulfate by an enzyme in the scalp called sulfotransferase.
Some research suggests tretinoin may:
Increase sulfotransferase activitySome peoples scalps don't have enough sulfotransferase, therefore treitinoin is used topically to convert it.
Alternatively, oral minoxdil can be taken if you're a non-responder to topical, because the liver has abundant sulfotransferase enzymes.
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"In reference to the man who fell in a fireplace and regrew his hair - you can actually get your scalp skin burned off.
It is called a phenol peel, far stronger than an ordinary chemical peel.
It is not sold online, you cannot buy the ingredients, only specialist beauty centers will offer it." -
has anyone ever considered scar gels for hair loss?
there is a lot of overlap with healing the skin and TGFb-1
many of them contain interesting ingredients that would stop inflammation in the scalp
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@wester130 going down the turpentine rabit hole, I googled around and found some research on terpenes supposedly reducing types 1 and 3 collagen -- bakuchiol, according to google. this also said terpenes are used for wound healing. I'm willing to believe that turpentine can straight up strip the collagenous paint out of one's scalp, lol
part of me wants to put turpentine on my head.
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@wester130 oh wow, ultrasound can break down fibrous tissue at the cellular level. There are clinics offering therapeutic scalp ultrasounds for hair health. https://onlinelibrary.wiley.com/doi/abs/10.1002/tee.23866
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some research i am doing on essential oils and vasodilation
rosemary and menthol are not potent, neither is euclayptus, neither make the top 10
patchouliguaiols ,
citral,
carvacrol + thymol ,
eugenol
are the most potent vasodilators if you are looking at isolated chemicalsfor patchouliguaiols, spikenard or simply patchouli oil would work
for citral, lemongrass or lemon verbena
for carvacrol + thymol , - oregano and thyme
for eugenol - clove essential oil would work
ginger, cinnamon, capscium, rosemary, menthol don't make the top 10 list.
rosemary for hair is the biggest scam going, look at the science, the chemicals in rosemary do not vasdodilate, -
@wester130 More horseshit from Big Rosemary.
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Rosemary (or sage) is not about vasodilation but about powerful anti-inflammatory activity by its diterpene carnosic acid, which is an antagonist to the human VDR and thus innate immunity. It may therefore work topically (to suppress symptoms for temporary healing but not to cure) for psoriasis and the like.
