Posts made by cupofcoffee

extremely real, my skull and bone all became thicker when i first started peating.

@Birk extremely real, but try other pro-erection stuff first.

on RPF, haidut mentioned how aspirin can help erections and i concur

they will speed up aging and cause oxidative damage

One of of the supposed "benefits" of antidepressants is increased neuroplasticity. Well, aspirin does just that without the cuck side effects

https://pubmed.ncbi.nlm.nih.gov/30012602/

Despite its long history, until now, no receptor has been identified for aspirin, one of the most widely used medicines worldwide. Here we report that peroxisome proliferator-activated receptor alpha (PPARα), a nuclear hormone receptor involved in fatty acid metabolism, serves as a receptor of aspirin. Detailed proteomic analyses including cheminformatics, thermal shift assays, and TR-FRET revealed that aspirin, but not other structural homologs, acts as a PPARα ligand through direct binding at the Tyr314 residue of the PPARα ligand-binding domain. On binding to PPARα, aspirin stimulated hippocampal plasticity via transcriptional activation of cAMP response element-binding protein (CREB). Finally, hippocampus-dependent behavioral analyses, calcium influx assays in hippocampal slices and quantification of dendritic spines demonstrated that low-dose aspirin treatment improved hippocampal plasticity and memory in FAD5X mice, but not in FAD5X/Ppara-null mice. These findings highlight a property of aspirin: stimulating hippocampal plasticity via direct interaction with PPARα.

AFAIK trenbolone has weird progestin-like activity, which is never a good thing (progestins are harmful and counterproductive, compared to progesterone)