@yerrag It's not clinical. The fact of the matter is that before you go making statements that progesterone stresses the body you need to have some concrete evidence. People saying that they feel worse while taking progesterone is not concrete evidence. If people take estrogen, and say they feel great. That doesn't take away from the fact that your increasing your chances of getting cancer and other health problems in the future.
Kate doesn't even come close to the experience that Ray Peat had. Even when she interviewed Peat years ago, she asked Peat about women feeling worse on progesterone. Stating that her "understanding" was that Progesterone releases estrogen from the tissues. Peat mentioned that it is released in a detoxed form (water soluble released by the kidneys) and not harmful. She also stated that Progesterone increases cortisol and Peat again corrected her, stating that progesterone can replace the adrenal hormones even if the adrenal glands are removed.
The fact that she keeps making these statements on podcast like Mercola even after Peat corrected her assumptions is really concerning. I really don't think she should be giving and health advice to anyone. Either she is not very perceptive, or she has malicious intent. Same Roddy, Georgi or anyone else making assumptions with no evidence.
Mercola has stated that he wants to make a progesterone product. So basically, she's giving him information that could undercut Peat's progesterone product.