Deuspower.shop is where i purchase my T3 and T4 (to Sweden). Ships without any issues.

@Korven This isn't exactly an answer to your question, but I've tried Tyromix and another source of synthetic thyroid. The other brand works a lot better and I wish I had tried something else than the Tyromix sooner. Haven't tried NDT unfortunately.

@nothingclever sounds like typical hypothyroidism

WHAT. This is amazing!

@Uroš Don't know what's the optimal but it makes sense taking it with food to slow the absorption to mimic the natural production and release. I just upped to 3 grains and I think the easiest way for me is to take the T3 three times a day with a bigger meal, with only the last meal also containing all of the T4. There's probably individual variance in what works best.

@LucyJ Okay! But yes if you're only on 1 grain I would not dismiss the possibility of hypo. Obviously tracking temps and pulse and all that. I dismissed it for a long time since I never saw any big improvements from the Idealabs tyromix/tyronene, but now I'm giving it a shot again with another brand.

@LucyJ said in MCAS:

@Jonk which multi do you take? I have pretty bad reactions to most supps. I think you replied to me on the old RPF suggesting a b vitamin but yeah everytime I try them I seem to get anxiety.(probably because they irritate my super sensitive upper GI) I'm really trying to find a way to commit to cronometer and meal plan as my goals for this year. So will start with one day and see how I go. Thank you

I think it's a Swedish brand.
https://www.svenskhalsokost.se/healthwell-multivitamin-man?da=14-46

It's trial and error for sure. Maybe it's safer with liver and oysters since most supplements have side effects. Have you read Broda Barnes Thyroid the unsuspected illness? You mentioned you're on one grain of thyroid. Highly recommend if you haven't read it yet. It's on archive.org

@LucyJ I'm in a similar situation. Started taking a multi vitamin recently and seem to help with digestion. Obviously dialing in thyroid dose is important, but making sure you get enough micro nutrients I think can be helpful if you've lacked in appetite for a while. I don't think you need cronometer every day but it can show you "oh I don't get enough zinc and magnesium" and then correcting that.

@GreekDemiGod have you ever tried NDT? Just curious, after reading Broda Barnes and some other book which references Barnes a lot, his patients seem to favor NDT over synthetic. I'm myself in the process of upping my synthetic T3/T4 to 30mcg/100mcg Wondering if NDT is something to potentially consider.

How many calories are you eating and do you hit all micros? Do you have any symptoms of gut dysfunction, food sensitivities etc?