@periander345 I got the help of a competent endocrinologist to optimized my dose of prescription NP Thyroid by Acella, which is a desiccated thyroid supplement available in the U.S for the treatment of hypothyroidism.
I started with 90mg (1.5 grains) of the med with this new endo because this was the dose of Armour desiccated thyroid that I had been taking for over 20 years. The NP Thyroid worked a whole lot better than the Armour and my rheumatoid arthritis inflammation resolved within the first week.
The medication was increased about every 6-8 weeks, after full thyroid panels were taken (blood testing) to verify my status. The reason why the medication is titrated up this way is because hypothyroid people tend to run on adrenaline instead of thyroid hormones. The body acclimates to the availability of the supplemented thyroid med and begins to rely on it instead of adrenaline. So the level of adrenaline goes down. Which makes you feel pretty lousy. But then the doctor increases the dose of thyroid med which makes you feel great again. For a few weeks. Then you repeat the blood testing, evaluation, and increase in medication. After 9 months of this process, my endo announced that my blood tests showed that I was taking my optimized dose. I remained on that dose for 5 years.
I get evaluated by the endo every 6 months. He lowered my dose end of 2020 because my body changed and my dose became too high, making me hyperthyroid. I now take 135mg of NP Thyroid per day.
The status of the thyroid hormones is very important and should be evaluated by blood testing (full thyroid panel) on a regular basis to verify that you are not taking too much because that can cause hyperthyroidism. Hyperthyroidism causes health problems, including thiamine deficiency, which has very similar symptoms as hypothyroidism. It can get really confusing if you are a "do it yourselfer" and are just relying on how you feel.