moderate protein restriction can cure all ills

Mauritio

I'm thinking about a modified version of protein restriction ATM.

If you'd have most of your protein at a certain point in time if the day , you'd get a big part of the MR/PR benefits.

In animals beneficial metabolic changes like an increase in FGF21 started showing after only 6h of the diet.
So if you eat a significant amount of protein only once a day, you get an 18h window of the benefits.

I thinks that's a reason why (intermittent) fasting works to some degree: You're restricting protein.

LucH

For neophytes:
MS= Metabolic Syndrome
DR = Dietary restriction
CR = calorie restriction
PR = Protein restriction
isocaloric dietary protein => iso => what is required; according to RDA.

Excerpt 1:
Protein restriction is sufficient to confer almost the same clinical outcomes as calorie restriction without the need for a reduction in calorie intake. The isocaloric characteristic of the PR intervention makes this approach a more attractive and less drastic dietary strategy in clinical settings and has more significant potential to be used as adjuvant therapy for people with metabolic syndrome.
Excerpt 2
More strikingly, both CR and PR improved insulin sensitivity by 62.3% and 93.2%, respectively, after treatment. Fecal microbiome diversity was not affected by the interventions.
Comment (LucH) :
It’s necessary to eat carbs at minima when ingesting meat. Not much. Otherwise you’ll get an insulin spike and the secretion of adrenaline and cortisol due to a lack of immediate fuel. Stressful and counterproductive.

LetTheRedeemed

@LucH

It’s necessary to eat carbs at minima when ingesting meat. Not much. Otherwise you’ll get an insulin spike and the secretion of adrenaline and cortisol due to a lack of immediate fuel. Stressful and counterproductive.

What? Are you saying if you eat more carbs with meat, you’ll lack immediate fuel? That it’s stressful and raises cortisol and adrenaline?

LucH

@LetTheRedeemed said in moderate protein restriction can cure all ills:

What? Are you saying if you eat more carbs with meat, you’ll lack immediate fuel?

No, WE need some carbs when eating meat. Not much required. A tomato or an orange IS fine. I Can show it with a graph if desired.

LetTheRedeemed

@LucH ok gotcha

serotoninskeptic

@Mauritio I do exactly this. Large window of sugar-only from morning past noon (5:00AM-1:00PM) with nothing but honey, sugar, and some fruit. Then I excercise and 3-4 hour fast to allow last bit of blood sugar to be used up, then a big protein dinner around 5:00 or 6:00 PM. Its going great I totally recommend the intermittent protein restriction idea.

LucH

@Serotoninskeptic said in moderate protein restriction can cure all ills:

then a big protein dinner around 5:00 or 6:00 PM. Its going great I totally recommend the intermittent protein restriction idea.

You'd better take first a fruit or a tomato if you don't want to burn muscles.
A few carbs is required, not to secrete adrenaline and cortisol afterwards.

Ecstatic_Hamster

The big issue with this is something that I noticed when I was doing the warrior diet.

You really can’t metabolize more than around 25 or 30 g of protein at a time.

So your protein may be too low if you’re doing only one protein meal.

And you’re loading yourself with a lot of protein at one time, which increases ammonia levels and stresses your kidneys.

jet9

great study! Thx for sharing.

@Ecstatic_Hamster pretty sure protein intake translation to increased muscle protein synthesis doesnt even begin topping out until 75-100g protein at one meal . irrespective of increased ammonia which maybe signals incomplete but not totally stopped protein utilization for better pathway