Reversal of hair loss in Mice with “sugar gel”
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@Hearthfire I have used it orally.
I think heavy metals can cause fungus overgrowth since they bind and incorporate heavy metals. And we're certainly getting heavy metals from all kinds of angles.
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@AinmBeo said in Reversal of hair loss in Mice with “sugar gel”:
Or getting the hair wet and making "rows" and applying it to the scalp at the base of each row?
This without making it wet. I apply it to the scalp, massage it and spread it with my fingers and after that comb my hair to spread it and increase circulation.
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@CrumblingCookie said in Reversal of hair loss in Mice with “sugar gel”:
I've been wondering whether BHB or butyrate would be better energy substrates to hair follices rather than dextrose.
Possible role of β-hydroxybutyrate in inducing inflammation in alopecia areata
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@Gaston said:
Possible role of β-hydroxybutyrate in inducing inflammation in alopecia areata
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Serum BHB levels were found to be significantly elevated in patients with AA compared with healthy controls, with higher levels correlating with severity of hair loss. BHB treatment increased inflammatory cytokine production in outer root sheath (ORS) cells, mimicking the inflammatory conditions seen in AA.
Hmm. That's a flip side. So the BHB seems to be strongly immunostimulative. Not necessarily merely proinflammatory per se. That leads us down to question the possibilities of what is underlying such (auto)immunological responses in alopecia areata, which may be due to specific or indistinct pathogen infection. And whether tackling such infection is possible rather than feeding or suppressing the immune response against it.
I can't find BHB serum measurements at the standard labs. Knowing those before would of course be nice to figure out which scenario one's in.
@Gaston said:
Those are good offers for BHB. Unfortunately they don't sell butyrate or a-KG yet.
@Hearthfire said:
I've seen some stuff about how potassium may be a key to reversing hair loss.
Thanks. If I'm grasping it correctly the effects of the potassium only replaces the use of minoxidil: So in all cases where minoxidil proves to be of no benefit there would be no benefits from potassium either.
That and the AA/BHB-connection really points to wanting to first figure out the underlying mechanism of one's hair loss. Or to at least set up a plan of one's own trials as in "if not AA, then...", "if minoxidil, then K" or "if not minoxidil/K, then..." -
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@CrumblingCookie The potassium bicarbonate at least is anti-fungal as well, so it could have multiple pathways to regrow hair. While also being much healthier/safer than minoxidil (even though minoxidil is pretty proven as a safe drug in correct doses and application)
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@CrumblingCookie What about ornithine a-ketoglutarate? I'm leaning towards trying this rather than BHB.
https://www.bulksupplements.com/products/l-ornithine-a-ketoglutarate-okg-powder
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@Mauritio
I put it on this morning.
Is there any reason to wash it off?
It does not seem leave a mess on the hair, after it dries. -
@AinmBeo No I just leave it in. This should increase absorption .
It's surprisingly practical. Even the sugar version is growing on me. Its sticky first, but after drying it works a little like a hair gel.Which version are you using ?
Im gonna add sodium butyrate this weekend .
