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    Experiments with transdermal hormones

    Bioenergetics Discussion
    testosterone transdermal trt hormones
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    • M
      metabolicmilk
      last edited by

      I have created a solution of

      25mg Tren
      25mg Test
      5mg Progesterone
      5mg DHEA
      5mg Exemestane

      Per ml

      I used DMSO & Coconut Oil in about a 90:10 ratio. This is mostly to stop the stinging/skin irritation from pure DMSO. They don't mix great so you need to shake before use. I would have preferred to use Vitamin E if I had on hand.

      It is working great so far. Definitely a lot stronger than my higher T experiments in the past.

      I have noticed zero sides from the Tren.

      It has been about 4 weeks

      W KilgoreK 3 Replies Last reply Reply Quote 0
      • Y
        yeyo12
        last edited by yeyo12

        I have

        vitamin e tocopherol oil
        ethyl alcohol
        base micronized test powder in my hand.

        can anyone help me with the recipe of how I can make a transdermal cream out of these?

        should I try to get isopropyl myristate as well?

        thank you!!

        M 1 Reply Last reply Reply Quote 0
        • W
          wester130 @metabolicmilk
          last edited by

          @metabolicmilk sounds interesting

          1 Reply Last reply Reply Quote 0
          • M
            metabolicmilk @yeyo12
            last edited by

            @yeyo12 using those ingredients I would do

            20% IPM
            50% alcohol
            30% Vitamin E

            Are you opposed to DMSO?

            Y 1 Reply Last reply Reply Quote 0
            • Y
              yeyo12 @metabolicmilk
              last edited by yeyo12

              @metabolicmilk

              thank you
              I have to get some IPM

              uhh, I've never really tried DMSO myself, but I've seen a lot of users have problem with it and I don't really want to smell -if it does that-

              Does it make you smell like garlic?

              M 1 Reply Last reply Reply Quote 0
              • M
                metabolicmilk @yeyo12
                last edited by

                @yeyo12 there was a post on old rpf about how using honey removes the smell. If you want a DMSO formula Id use 70 DMSO : 20 Vit E : 10 honey

                1 Reply Last reply Reply Quote 0
                • KilgoreK
                  Kilgore @metabolicmilk
                  last edited by Kilgore

                  @metabolicmilk
                  What is your goal with this?

                  Which testosterone & DHT bases are good for topical application? (fromPPL)

                  Also whats the Exemestane for?

                  M 1 Reply Last reply Reply Quote 0
                  • W
                    wester130 @metabolicmilk
                    last edited by

                    @metabolicmilk what other results are you getting?

                    M 1 Reply Last reply Reply Quote 0
                    • M
                      metabolicmilk @Kilgore
                      last edited by

                      @Kilgore anti E

                      1 Reply Last reply Reply Quote 0
                      • M
                        metabolicmilk @wester130
                        last edited by

                        @wester130 grow bigger while losing fat. It's working.i feel like my bones are growing

                        W 1 Reply Last reply Reply Quote 0
                        • W
                          wester130 @metabolicmilk
                          last edited by wester130

                          I put DHT GEL on my Nether-Regions: Insane EQ, Painful B*ners, Masculinity, and SIDE EFFECTS

                          Youtube Video

                          1 Reply Last reply Reply Quote 0
                          • UncoverU
                            Uncover @metabolicmilk
                            last edited by

                            @metabolicmilk I agree it can have strong health effects. Its interesting how some people here are wondering why so many are interested in DHT here. It has some of the most potent anti stress effects a molecule can have and literally is produced in healthy men. When one gets into a stressfull state testosterone will slowly decline in comparison to DHT which plummits. Its extremely anti estrogenic, pro gaba, anti adrenaline, anti cortisol, anti inflammatory. I think the people who didnt notice anything either needs to improve their health situation abit more first, or wasnt eating nearly enough. I would consume 6-7k calories when I was top health and was completely shredded. In this state my natural test was higher than avarage but my dht was extremely high. Later I started also adding 11-keto dht and androsterone and saw even more benefits. After alot of stress and lack of good food for 1.5 year the thing that helps me recover to my old state faster is not only good food, but also hormones...

                            albionA 1 Reply Last reply Reply Quote 0
                            • KilgoreK
                              Kilgore
                              last edited by Kilgore

                              What do you guys think about a solution like this?

                              30mg T
                              5mg DHT
                              5mg DHEA
                              5mg Progesterone

                              per 1ml Vitamin E.

                              What about adding pregnenolone?

                              Crypt KeeperC alfredoolivasA W 3 Replies Last reply Reply Quote 0
                              • Crypt KeeperC
                                Crypt Keeper @Kilgore
                                last edited by

                                @Kilgore I could not get T to dissolve in a reasonable amount of Vit E. It's just not a good solvent alone. There's a thread somewhere that I posted in awhile ago.

                                alfredoolivasA KilgoreK 2 Replies Last reply Reply Quote 0
                                • alfredoolivasA
                                  alfredoolivas @Kilgore
                                  last edited by

                                  @Kilgore That's a good plan, I would take it orally though, not transdermally. The biggest issue I faced with creating a vitamin E steroid solution, was finding the right vitamin E solvent; 1.) Many Vitamin E / Tocopherol oils, are either alpha or mixed tocopherols diluted heavily with a seed oil like sunflower oil or wheat germ oil. 2.) Some are sold as "vitamin E oil / tocopherol oil" but are actually only wheat germ oil, due to it's high vitamin e content.

                                  Both alpha and mixed tocopherol work equally as well, according to haidut via email.
                                  I use https://www.mysticmomentsuk.com/products/vitamin-e-natural-vitamins?variant=2738367922200
                                  It's 70% mixed tocopherols and 30% sunflower oil, which of course isn't perfect, but the sunflower oil consumed is minimal. It's the best value source of high-concentration vitamin E oil I could find in europe/UK, despite it using more expesnive mixed tocopherols. I couldn't find affordable alpha tocopherol oils in Europe, and this mixed tocopherol product is more concentrated and cheaper than any tocopherol oil I could find on iHerb.

                                  KilgoreK 1 Reply Last reply Reply Quote 0
                                  • alfredoolivasA
                                    alfredoolivas @Crypt Keeper
                                    last edited by alfredoolivas

                                    @Crypt-Keeper I can personally make a progesterone and DHEA vitamin E solution, where I can dissolve 150mg of each into 1ml of vitamin E. So that's a 30% solution of DHEA and progesterone dissolved in vitamin E.

                                    I pre heat the tocopherol first in the microwave to a high temperature, and then throw in the powders, swirl them vigorously, and put it back in the microwave, and warm the solution, and swirl it again vigorously. I then inspect the oil by shining a light through the bottom of the jar I brew the solution in, and I can see little to no undissolved hormone.

                                    I failed to make a pregnenolone solution with vitamin E at first; but I found out that the trick to making steroid solutions whether that be in vitamin E, or benzyl benzoate with steroid esters, is to pre heat the solution well before adding the hormones in.

                                    1 Reply Last reply Reply Quote 0
                                    • KilgoreK
                                      Kilgore @alfredoolivas
                                      last edited by

                                      @alfredoolivas said in Experiments with transdermal hormones:

                                      That's a good plan, I would take it orally though, not transdermally.

                                      Why?

                                      Earlier in this thread Brightside explained the benefits of transdermal application over oral:

                                      Few reasons. For me, injection seems like a primitive method, while topical is a much more elegant solution. But the general reasons would be:

                                      risk of infection
                                      introducing needless PUFAs
                                      long term suppression and need for PCT to stop
                                      more of a commitment/big deal to do (buying potentially contaminated UGL gear or going to a TRT clinic)
                                      more often a need for AI (since topical generates more DHT)

                                      Additionally, this is only for TRT, but people might want to use other hormones like P5, P4, DHEA, DHT, Exe, 5aDHP, etc. Using topically is convenient and can offer a high absorption compared to oral, or it can provide an alternate metabolism. (like in the case of DHEA or T).

                                      I like these benefits, but I have 0 experience with any of this so I am open to any ideas.

                                      As for the Vitamin E I have is from NOW. I know its not the best but I don't mind it for a first try. Next time I might try this as it was recommended to me by a fellow peater.

                                      alfredoolivasA 1 Reply Last reply Reply Quote 0
                                      • KilgoreK
                                        Kilgore @Crypt Keeper
                                        last edited by

                                        @Crypt-Keeper Thanks I'll look through it.

                                        1 Reply Last reply Reply Quote 0
                                        • albionA
                                          albion @Uncover
                                          last edited by

                                          @Uncover Well said.

                                          1 Reply Last reply Reply Quote 0
                                          • E
                                            Ena
                                            last edited by Ena

                                            I mix progesterone with vitamin E powder and some drops of coconut oil.

                                            I don't make a solution to store. I simply put the day's ingredients on a spoon, mix with a finger for 2 seconds, and apply directly to my gums.

                                            I store coconut oil in this dropper container
                                            https://www.amazon.co.uk/gp/product/B0BY8Y6S8Z/

                                            I use this Vitamin E powder (the capsules are easy to open)
                                            https://www.timehealth.co.uk/product/vitamin-e-complex/

                                            1 Reply Last reply Reply Quote 0
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