Glucose loading cures everything?
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@gentlepotato Interesting! Thank you for sharing! I'm saving the video links to watch as time permits.
Regarding retracing, I believe Dr. Stephens explanation is that you may become more aware of symptoms as your brain "wakes up." I think that's likely true, but there's also something else happening. In homeopathy and other alternative methods of energy healing, as layers of pathology are peeled back, the revisiting of old symptoms will be likely. In any sort of trauma, your brain tries to protect you, so I envision those experiences being covered over with scar tissue, buried deep in your psyche, but never really healed. So as the brain begins to heal you may feel many emotions as well as physical symptoms related to traumatic events experienced years ago.
I haven't yet heard a good scientific explanation for how high amounts of glucose will trigger this process, but I think supporting healing with "energy medicine" is advisable.
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@gentlepotato said in Glucose loading cures everything?:
Now many of them already work relatively well, despite the incredible fatigue. It's like all my parts work better, except the motor. In that sense I may experience less "detox" symptoms, because when the motor is working, the pathways for elimination are ready to be ramped up. Any “detox” symptoms I’ve had have been incredibly gentle though.
Interesting language GP.
@gentlepotato said in Glucose loading cures everything?:
NOW FOR SOME EDUCATED SPECULATION:
It's eye music. What internet forums were made for.
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@gentlepotato said
If you think you have a “glucose limitation” look up the hormones produces in the hypothalamus, pituitary gland and adrenals, and you might find the explanation for your weird symptoms.
Do you mean to say that e.g. a suppressed circadian TRH curve or a stunted TSH response to exogenous TRH (i.e. a functionally atrophied pituitary gland) could be commonly associated with overall glucose limitation?
Reading your long post had me impressed as it means some of your brain was clearly working well enough to start and accomplish that.@gentlepotato said
I am guessing that with hypoglycemia there’s often less ability to store glucose. I think maybe the liver (and body overall) will store fat instead, when it’s not able to store glycogen (or doesn't have any extra glucose to store?
Which is another reason I think taking big doses won’t be helpful: I don’t think the body is able to store the extra glucose well - yet. That will change with time I think, because if the liver is storing fat it will start to release it and store glucose instead.
Interesting. And maybe this relates to what I am going through described further below?
@S-Holmes said
I think supporting healing with "energy medicine" is advisable.
What measures do you mean by "energy medicine"?
@Jaffe on noticing any difference between dextrose products' quality:
I have not yet switched to the organic dextrose but will report when I notice any differences or when not.Experience update:
4 weeks into dextrose now.
Last Tuesday/Wednesday I had made the large increase from 5x c. 56grs to 5x 100grs daily.
To my surprise this time I felt weak and drowsy for only one day, in contrast to my previous increases.
On the plus side I have not been feeling "snackish" anymore in between my dextrose servings. So the higher serving size for me currently lasts longer than the previously lower amount.
By Friday the anticipated digestive troubles began to set in again, starting with terribly oily and unformed BMs. I have eaten no fats and no oils within the past week. Seriously zero.
Throughout Saturday I had mucuous watery diarrhea. Followed by a some flatulence.
Since Sunday it's awfully oily BMs again.
I took activated charcoal and psyllium on Friday and on Sunday. I am thinking that I may need regular daily GI binders. I don't know if cholestyramine would help and have just drunk a 4grs package of that.
Also, on Friday evening I had started to add 2grs BCAAs to every dextrose serving because of the tryptophan shift brought up in the other thread here.
Clearly, adding BCAAs did not alleviate the digestive issues as hypothesized but probably even enhanced the GI issues from upping dextrose in me enormously.
And I can't say whether this is ought to be a categorically "good" thing to my body's benefit.
Practically and right now there's definitely something very off.I appreciate all helpful suggestions on these reactions and how to manage them.
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@CrumblingCookie My preferred energy medicine is homeopathy, but there are others that are also quite useful.
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@CrumblingCookie said in Glucose loading cures everything?:
Do you mean to say that e.g. a suppressed circadian TRH curve or a stunted TSH response to exogenous TRH (i.e. a functionally atrophied pituitary gland) could be commonly associated with overall glucose limitation?
Reading your long post had me impressed as it means some of your brain was clearly working well enough to start and accomplish that.Thank you for that lovely reflection! I can only assume that alongside the pro metabolic way of eating, my meditation practice (ten years in August) has been protective and supportive of my brain.
To your question: Yes. A lot of the research I've read about neurological diseases have symptoms of, and more objective findings, of one or both.
Again from here, the article about Hypocortisolemic ASIA (that describes the Itaconate shunt, without knowing it): https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1422940/full?fbclid=IwZXh0bgNhZW0CMTAAAR3zhrexW5QVOLR_K9X7KQYKokcY3NflDVcwjFY5mJ-UDY0VOV6QiOzLqqE_aem_mu738vb0NJaI3RSXBno-vw
"This process might begin with a deficient CD4 T-cell response to viral infections in genetically predisposed individuals (HLA-DRB1), followed by an uncontrolled immune response with CD8 T-cell hyperactivation and elevated antibody production, some of which may be directed against autoantigens, which can trigger autoimmune hypophysitis or direct damage to the pituitary, resulting in decreased production of pituitary hormones, such as ACTH. As the disease progresses, prolonged exposure to viral antigens can lead to exhaustion of the immune system, exacerbating symptoms and pathology."
Edit: Just read your question again, and I am not 100% sure I understood it correctly. Let me know if I didn't!
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I had my first appointment with the good doctor today. It went really well. He says I'll need to work up to at least 10 Tbsps per dose. I'm currently at 4.
After nearly a month on the protocol, I realized today during the consultation that I haven't had suicidal thoughts in about 2 weeks. 2 of my 3 younger sisters took their own lives within the past 4 years...one by intentional overdose and the other used her handgun. This is huge for me and I feel very encouraged.
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That’s amazing resultat, @S-Holmes. I’m so sorry you’ve lost your sisters to suicide.
What is the reasoning Stephens give, when he says you need to up the dose? And what are you hoping that will change, when you're already seeing such amazing results with the dose you're on?
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@gentlepotato
Thank you. Life wasn't kind to my sisters and although still very sad, I find comfort in knowing they're no longer suffering.I've had CFS for as long as I can remember, and adult failure to thrive (couldn't gain weight except during pregnancy). I've been able to control symptoms throughout my life using constitutional homeopathy, then at menopause everything took a turn. I've had tinnitus for 15 years. I'm dealing with long covid after contracting covid 3 times: fatigue and chronic sinusitis impacting eyes and causing congestion.. Post covid I also developed what I call sundown anxiety. It's a horrible sinking discomfort that would stop me in my tracks every day like clockwork as soon as the sun set. (I could tell when the sun set without seeing it.) I learned that I could control it with a little Coke, and now glucose.
A stressful childhood, a car accident, and a slip on the ice, hitting my head hard on a concrete step are likely the primary mitigating factors in my pathology. Dr. Stephens is 100% confident that I will be cured.
His consulting fees are $0 to $175. What I pay is completely up to me. If, as some claim, glucose therapy isn't legitimate, I have yet to see what's actually in it for him.
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@S-Holmes Bless you. I can identify with the adult failure to thrive as you mention (and Stephens does as well). I heap piles of shame on top of this, and I grieve of life lost to survival mode living.
It will be amazing to see amazing people like you fully restored to full potential. I don't like the word recovery, as I'm not sure what previous version of me I would even want to recover to. It sounds like you and others that have stumbled on this treatment would probably relate. I'm really inspired by your story. You deserve to be (and will be) fully healed. Thanks for your sharing.
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@GlucoseOrBust My heart goes out to those like us who are forced to live an entire life in survival mode, never knowing we were intended to find pleasure just living out each moment. I had a glimpse of that for a day around the time my suicidal thoughts vanished. I pray you can find that and that I can get back to it.
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Please share your ideas for helping the glucose water go down easier. I take it in cold fizzy water with lime or lemon added. Still seems like drinking syrup but it does help.
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@S-Holmes said in Glucose loading cures everything?:
His consulting fees are $0 to $175. What I pay is completely up to me. If, as some claim, glucose therapy isn't legitimate, I have yet to see what's actually in it for him.
He seems like a very well intentioned person, and amazing he is able and willing to offer consultations at the price someone can pay. What is the easiest way to get a hold of him? I still haven't heard back after inquiring through his homepage.
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@gentlepotato It took me a few weeks sending multiple messages. He apologized for that. I think because of the discussion here and on the RPF he has suddenly gotten a new influx of patients. If you would like to pm me your phone number I can text it to him.
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@S-Holmes thank you for the offer! I'm in Europe, so different time zone completely, therefore email would be preferred. If you have his email, would you be able to send it to me?
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@gentlepotato Sure. Will PM.
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My gut feeling tells me to explore fat with the glucose, and I've tried to search the forum about this without finding anything (I find the search function doesn't work well - am I the only one?): What fat source has the most nutrients per grams that would be supportive, in terms of neurotransmitters, brain health, Krebs cycle, mitochondria?
The gut feeling is likely informed by the video by Rob Phair that I posted the other day, where he talks about the GABA shunt.
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Without assessing the validity of your gut feeling (maybe you don't need exogenous fatty acids but more endogeneous synthesis with the help of B5 and B6 and B7?),
@gentlepotato said in Glucose loading cures everything?:What fat source has the most nutrients per grams that would be supportive, in terms of neurotransmitters, brain health, Krebs cycle, mitochondria?
I'd confidently say cocoa butter (pellets) and beef or lamb tallow to this, as they contain lots of valuable long-chain saturated FAs and stearic acid (for mitogenesis) especially.
Or instead of tallow: Fatty cuts of beef or lamb and eat/keep/separate the fats after c. 3hrs of low-temp cooking.I haven't yet read through that paper you posted and the itaconate ways.
Thanks @S-Holmes. Not sure which homeopathic remedy would be right for me right now. But I've added Glechoma tincture for my detox suppport (Lysimachia=Gold Coin Grass=Jin Qian Cao may be more available to some). -
@CrumblingCookie said in Glucose loading cures everything?:
Without assessing the validity of your gut feeling (maybe you don't need exogenous fatty acids but more endogeneous synthesis with the help of B5 and B6 and B7?),
Thanks, I'll look into that!
I'd confidently say cocoa butter (pellets) and beef or lamb tallow to this, as they contain lots of valuable long-chain saturated FAs and stearic acid (for mitogenesis) especially.
Or instead of tallow: Fatty cuts of beef or lamb and eat/keep/separate the fats after c. 3hrs of low-temp cooking.Thank you! I think my gut feeling often knows, but I need to do so much unlearning about food to be able to listen well to it. It's getting better, but one way to unlearn is to research and ask others. And hearing that answer make it easier to tap into the gut feeling I was having.
Which has been asking for cocoa, but I thought it meant powder, because that's all I have at the moment. It also asked for more tallow, but I keep forgetting to use it because it's in the fridge and not on the countertop. Gonna have to keep some next to the stovetop. I always keep the tallow when I make oxtails, so I've got lots, and use it as a face cream too. Tallow is amazing.
I will experiment a little and report back.
How are you getting on though, @CrumblingCookie?
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This just happened. Dr Stephens had asked me about sleep and dreams. I've only ever had disturbing dreams or nightmares that wake me up shaking with fear. He told me that my nightmares will end. He treats about 40 combat veterans with ptsd (and nightmares). All are free of their ptsd symptoms. And last night I had the most amazing and comforting dream. The first I remember, ever.
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@S-Holmes Beautiful report! Keep em coming.
