Posts made by Insomniac

even better than a cup

@LucH I'm sorry, this was the study that I recalled for anyone interested.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577458/

Results

Postprandial serum endotoxin concentrations were increased after a meal rich in saturated fatty acids and decreased with higher n-3 PUFA intake. Compared to the no oil control, fish oil and CLO which are rich in n-3 fatty acids reduced ex vivo endotoxin Papp by 50% (P < 0.05). Contrarily, saturated fatty acids increased the Papp by 60% (P = 0.008). Olive and vegetable oils did not alter intestinal endotoxin Papp.

@LucH I believe I was recalling this study regarding lps being absorbed better with saturated fats but I've seen a few over the years.

https://ajcn.nutrition.org/article/S0002-9165(22)01122-4/fulltext

Discussion
This double-blind, randomized crossover trial demonstrated that a single meal high in saturated fat can impede attention—resulting in reduced detectability—compared with an identical meal high in monounsaturated fat. Importantly, each woman consumed both meals, and thus between-person biological or genetic variability did not account for the observed meal effect. Endotoxemia played a role as well, as women with elevated endotoxemia markers had poorer attention across CPT testing occasions. As the gastrointestinal tract is the primary source of endotoxin (7), these results implicate bacterial endotoxin translocation from the gut to the bloodstream (“leaky gut”) in sustained attention deficits similar to prior findings (5, 28–31).
The interaction between endotoxemia and experimental meal type was especially noteworthy: a single high-saturated-fat meal caused relatively poorer postmeal cognitive performance only in the context of low endotoxemia. That is, endotoxemia erased between-meal differences, impairing postmeal attention regardless of meal type. Notably, participants who were 1–2 SDs above the means for endotoxemia markers approached clinically significant t-score values (>60), indicating possible cognitive impairment. Although a single meal high in saturated fat did not induce clinically significant levels of cognitive impairment, repeated exposure to high-saturated-fat intake may do so.

@Sugarnotsnow I think it was this one.
https://bioenergetic.forum/topic/2010/mead-acid-desaturases-and-accelerating-pufa-efa-depletion/2?_=1727467751483

@Sugarnotsnow TexugoDoMel had a great post about oleic acid being useful to possibly induce efa if I recall.

I have mixed feeling about monos but the do seem to be less likely to increase endotoxin absorption from the gut than saturated fats.

@LucH Very useful info. I see it wouldn't be good to make them the base of a diet without some planning.

I've read soaking could help a little.

@LucH Well I think that's manageable. I haven't found a food with absolutely no issues when you include environmental toxins, heavy metals etc etc.

@Sugarnotsnow It's hard to find decent clean foods that aren't high in pufa. I hate to take one more food off my short list.

@Sugarnotsnow

It's worth mentioning that you get lots of glycine from that form which is really good for sleep.

@LucH Why limit macadamia nuts to 1 oz? I couldn't find any issues with them at all.

Posted by the raypeatforum.com domain owner charlie:

Change is in the air! Our forum has transitioned from the RayPeatForum.com domain to the LowToxinForum.com domain. I decided it was time to move away from Ray Peat's name. Yes, we will still discuss his work here, just as we discuss everyone's work, but we have changed the domain name. It is clear that this new paradigm, the low toxin lifestyle, is where it's at. The results in the community speak for themselves, and I have no doubt this movement will significantly benefit at least a portion of society.

Ironically, a few days after I decided to switch away from the RayPeatForum.com domain, Mrs. Peat contacted me asking us to move off the domain. I expressed that even though I have written and verifiable permission from Ray Peat to use the domain, I am not interested in litigating his widow. When she contacted me I took it as a sign that I was doing the right thing by moving off the original domain.

As we launch our new forum domain, I am running a special on subscriptions. I have reduced the subscription fee to $2 a month or $20 a year. We are maintaining the paywall for posting to help keep troublemakers out and elevate the level of discussion. If you have a current subscription at the higher price, you are welcome to cancel it and renew at the lower price, or you can continue to help support our forum at the prior subscription price. You just need to contact Stripe or PayPal and have them cancel the current subscription if that's the route you choose.

This is a great and exciting change, and I have a feeling this forum is about to reach new heights as we do our part to help make health great again.

Bioenergetic member Mike Fave (aka CLASH) "reviews the scientific studies used as references in Grant Genereux's book "Poisoning for profits" on the supposed harmful effects of vitamin A on human health."
https://www.youtube.com/watch?v=sAslLuARWpo