@tk said in Reintroduced Wheat - Confused With Results:
I suffer from POTS and gastroparesis among plenty of other issues. I also seem to have chronic SIBO/SIFO that my body is unable to rid.
Here is a clue
The Downside to High Oxalates – Problems with Sulfates, B6, Gut and Methylation
https://www.beyondmthfr.com/side-high-oxalates-problems-sulfate-b6-gut-methylation/
Excess oxalate (> 50 mg/d) exhausts sulfur. If there is a lack of sulfate, a lack of methylation happens soon after. Biochemical chaos is in sight.
Detailed explanation:
When sulfate levels are low, the body won’t just have disturbed liver function, it will also suffer with all kinds of hormone problems. The reason why is that the body uses sulfate molecules to inactivate hormones. In a 2008 study also using NaS1 deficient mice, researchers showed that blood levels were reduced 50% for cortisol, 30% for DHEA, and 40% for DHEA-S.27 This massive loss of blood hormones was accompanied by a 1500% increase of cortisol spilt into the urine and lost as well.
(…)
We know that hormone production requires energy, vitamins, minerals and essential fatty acids – things people with chronic health issues have in short supply. (…)
Excerpt from my forum (in French, translator needed but with links in English)
Impact négatif de l’oxalate sur le métabolisme : Chaos biochimique !
Negative impact of oxalate on metabolism: Biochemical chaos!
https://mirzoune-ciboulette.forumactif.org/t1959-impact-negatif-de-loxalate-sur-le-metabolisme-chaos-biochimique#28275
Most people are unaware of the problem.
Oxalates generate great biochemical chaos in the body (3), more than any other component (except mercury).
Problems linked to sulfur (and by extension histamine and salicylates) can be caused by a struggling metabolism, which is no longer able to process excess foods rich in oxalates. Oxalates interfere with sulfate transport. It is the entire metabolism (the liver via different systems linked to sulfation, methylation) and the deprivation of nutrients useful to intestinal bacteria, which are altered. For example, pyroxidine (B6) is depleted in this oxalate neutralization process. We need B6 in the process of exchanging an oxalate molecule with a sulfate molecule. B6 is necessary for the functioning of approximately 150 enzymes linked to approximately 60 genes that regulate neurotransmitters and liver detoxification as well as general metabolism. (4)