Posts made by LucH

OK but I won't expect much "evidence". What it does is under the radar.
Conjunction of several "ingredients" is required when trying to optimize energy.

@Hearthfire said in CoQ10 Experiences:

I'm on 400 mg a day of Ubiquinol. Will update experience.

Hi,
It would be interesting to split the take: 200 mg ubiquinol in the morning and 100 mg at midday, with a meal where there is some fat. Liposoluble.

Hi,
What about a re-initializing process, in a soft way when the natural postprandial contractions occurs through the MMC.
I’ve done it.
Just to be clear about the MMC, being a natural movement but in a sleepy phase.
The migrating motor complex (MMC) is an electrical and contractile activity of digestive motility which takes place in the inter-digestive periods (between two meals), and interrupted by food intake. Each MMC is accompanied by an increase in gastric, pancreatic and duodenal secretions. They are thought to serve to evacuate contents in the small intestine between meals, and also to transport bacteria from the small intestine into the colon. An alteration of this phase notably favors the development of chronic bacterial colonization of the small intestine, a source in particular of bloating, diarrhea, or even steatorrhea, of the majority of food intolerances. When contractile activity is low, we then speak of lazy intestines. Support and rehabilitation is often necessary, with a prokinetic.

@Insomniac said in Is a slowing pulse and lowered body temperature while dieting a problem?:

of course.

My log:
https://mirzoune-ciboulette.forumactif.org/t2074-fast-diet-ou-le-regime-5-2-journal-de-suivi-luc#29929
You can open a log if desired and use English language.
https://mirzoune-ciboulette.forumactif.org/f71-espace-soutien
Hidden from internet search.
=> Insomniac – diet log.
A short presentation would be appreciated (context). No need to develop if you don’t want to but it’s easier to understand how and why.

@Insomniac said in Is a slowing pulse and lowered body temperature while dieting a problem?:

Do you feel the lowered temperatures etc is more harmful than the benefits of being at an ideal weight?

If low temp can't be changed yes.
I'm currently following a 5.2 diet , 1 kg / 2 pounds lost per week.
Need to make a staple now because of light eczema, before it overwhelms the capacity of my liver to get rid of the toxins. Eczema is often the sign of
I took one drop of EO thyme verbenone with one tsp coconut oil 20' before the breakfast this morning. To help a lazzy liver to work best. Eczema is often the sign of clogging; clogging of the emunctories. Too many toxins + LPS (....)
Note: I can give a link to my log if desired.

@Insomniac said in Do people here worry about a slowing pulse and low temperatures during weight loss?:

this sabotaged my weight loss efforts.

Make a pause, without stopping diet for sure.
What kind of diet have you followed?
Note: If you slow too much your metabolism, you won't be able to recover a stable weight. Measure is all. Need to stabilize.
=> When slowing carburation too long, there is an impact on thyroid. So that you'll take the weight back. See the wall in front of you, not the target. You have to jump above the wall. But first you have to make a staple: Press the button pause.

@Jakeandpace said in B12:

Been meaning to try b6.

Mind the kind. PLP OK; no PNP.
And if you overload, you'll get problems with the brain (GABA short).
I did it 5 days on 7 for 3 weeks. Stop one week, Then again.

Pyridoxine PLP as pain inhibitor in peripheral neuropathy
Efficacy of Vitamin B1, B6, and B12 in Peripheral Neuropathy
https://mirzoune-ciboulette.forumactif.org/t2041-english-corner-b6-leads-to-decrease-of-cytokines-in-pn#29659
People taking a UL dose of 25 mg on a usual way for peripheral neuropathy could have problem or not, depending on the fact that B6 has a half-life of up to 30 days. So repetitive small doses taken over a period of months can accumulate, resulting in high blood concentrations. Too much of a good thing is bad (U-shaped curve benefits with pyridoxine). Evidence from the literature [1] has shown that chronic intake of high levels of vitamin B6, higher than the recommended dosage, leads to severe and progressive sensory neuropathy accompanied by ataxia or loss of control of bodily movements.
Note's Editor: "Evidence from literature" => Not so evident at the end of this post.
When people taking medications for treating health problems that increased catabolism of pyridoxine (like epilepsy or chronic lung diseases), they should adapt their treatment in agreement with their therapist. Taking UL B6 is going to change the posology needed.
Apart from effectively reducing homocysteine levels, when targeting the right dose of B6 (in association with folate, vitamin B12, not necessarily every day), we should take into account a right window for the degradation of the pyridoxal metabolites to 4-pyridoxic acid. Otherwise, there will be a return of the crank with UL of B6. Expressed in a different way, we need to take breaks to optimize profits. More details will be given on the way to adapt the levels when taking high doses of B6 and the kind of B6 you could manage with.

NB: 30 to 60 % people are deficient in the methylation process. So when taking simple forms of cobalamin (B12) or folic acid, it doesn't function. Useless.
See interaction on the graph:

See too:
English Corner – Vit B6: How much is too much?

Hi,
I don't watch / listen to a video or read a PDF when there is no comment (=> why it's interesting / it's worth watching it).
And when this video lasts rather long (30' or 50'), main points would be appreciated...

@Mossy said in Assumimg I have dysbiosis gut is made worse by any soluable fiber and insoluable:

Do you find these (EPS Melissa and curcumin) to be better than the previous supplements you've recommended (enzymedica lipogold, Betaine HCL) or in addition to?

The don't have the same functions. Wait to get the whole stuff if money is a problem. But perhaps you don't need some of them.
Enzymedica lipogold: Enzymes to help digestion, specially adapted for lipids, but not only.
Betaine HCL: when protein digestion takes too long. + Help for light bloating. Once a day. This product optimizes the action of bile.
Meat must the be eaten preferably at midday when bile secretion is optimal.
EPS curcumin and EPS melissa:
Required first to calm irritation down (IBS). The most important.
Whenever no other drugs functions because of inflamed walls.
Melissa has a brain action too (connection with stress and mental through vagus nerve).
Curcumin has several functions: help and protect liver. Lay inflammation down (only tolerated when in liquid form because curcumin powder has small crystals).
NB: Not so easy to find / buy. In a phytodrugstore or internet. Make a search with French words to see what it looks like.
https://www.monherbo.fr/eps-herboristerie-depuis-1942-nantes-eps-bourgeon-aromatherapie-plante-en-vrac/1117-eps-curcuma-pileje-phytoprevent-herboristerie-depuis-1942-nantes-eps-bourgeon-aromatherapie-plante-en-vrac.html
=> Click on the name to see the functions. In French (translator needed).
From labo Pileje.

Note: to facilitate digestion, the rule 2/3 1/3 is advised.
1/3 = a small portion. A small portion of protein when eating starch (potato, pasta).
E.g. 2 eggs with pasta.
No legumes since they contain anti-proteases (enzymes to digest proteins). Green peas and lentils are easier to digest when the digestion is OK. => Rice + peas or lentils = full spectrum of amino acids. Better to let lentils soak the day before, in water. Change the water to cook. No salt before the end of cooking (softer).

@foxgelb said in Bind bile:

How would I know it hurts the stomach walls?

With what you've said, it's not "pain wall" due to thin mucus.
If localized at one point, it could be CaOx (lithiasis).
If you have "eaten" more than 150-200 mg ox per day (carrot salad + ... ), you've overridden your capacity. The liver can only handle 50 mg ox a day.
If so, need for potassium citrate to solubilize the stone.

Hi,
Do you say you have excess bile because it hurts the stomach walls?
Give details, please?

@Mossy
IBS and fiber
If someone has IBS, he may find that bran is not something he tolerates well. Bran has a lot of insoluble fiber, which can make IBS symptoms worse. Oat bran contains rather much oxalate too. Oat flakes are ok and rich in calcium.
You should still try to get fiber in your diet, but you may find that focusing on sources of soluble fiber is a better option, adapting the amount and the frequency to what you tolerate.
I’d calm the irritation down first. When very sensible, EPS Melissa and curcumin.
EPS = Extrait de Plantes Standardisées (=> Plant extract liquid). Very soft approach for irritable bowels.

@Samyo said in Assumimg I have dysbiosis gut is made worse by any soluable fiber and insoluable:

i was day 4 into this carrot salad, i cant take it anymore, my skin is destroyed, my forehead proper dry, skin barrerier now damaged

Were you eating a carrot salad more than once a day? Without making pause / a turn-around?

*) Estrogen Induces Hypoxia across Various Biological Sites – Ray PEAT
https://raypeat.com/articles/articles/imprinting.shtml
=> Estrogen brings vasodilation and induces hypoxia. This is mediated by increased levels of prostacyclin and nitric oxide as well as decreased levels of endothelin-1.
DOI: 10.1097/CCM.0b013e31817d1a92
Why do vessels dilate in hypoxia?
Pulmonary arteries (PA) constrict in response to alveolar hypoxia, whereas systemic arteries (SA) undergo dilation. These physiological responses reflect the need to improve gas exchange in the lung, and to enhance the delivery of blood to hypoxic systemic tissues.
DOI: 10.1016/j.resp.2010.08.007
*) Estrogens stimulate cortisol production

• HPA function is highly influenced by circulating glucocorticoids induced by estrogens.
• In the presence of estradiol there is a dysregulation of the HPA axis (hypothalamic-pituitary-adrenal axis).
  How does the HPA axis work?
  How does the HPA axis work?
  • In response to a stressful situation, your autonomic nervous system triggers your hypothalamus to release corticotrophin-releasing hormone (CRH).
  • CRH triggers your anterior pituitary to release adrenocorticotropic hormone (ACTH).
  • ACTH then triggers your adrenal glands, specifically your adrenal cortex, to release cortisol.
  The HPA axis is meant to have a fine-tuned negative feedback loop (to tell the brain to stop releasing cortisol)
  https://my.clevelandclinic.org/health/body/hypothalamic-pituitary-adrenal-hpa-axis

Shortly said: No need to understand how. Keep in mind that too often or too long is not adapted.

@pittybitty said in Can somebody explain to me what estrogens really are?:

Thanks, what does "stress hormone" specifically mean here? It doesn't sound related to the hormones that are usually called "stress hormones" like adrenalin or cortisol.

When estrogen takes place, it is followed by serotonin. So, too long or not adapted (sensitive ground), it is counterproductive. Useful but must be counterbalanced.
Like a soft / light heat. Measure is all.
We could make a comparison with calcium: needed for contraction but must be followed by rest.
RP has explained it in one article. I come back with one excerpt.

@natureman said in Can somebody explain to me what estrogens really are?:

It's a stress hormone. You need stress hormones to develop, thrive and survive.

The problem is the excessive and unopposed (by enough progesterone) action of it.

Thanks for summarizing
Are estrogen and estradiol the same thing?
Estrogen is often referred to as estrone, estradiol, and estriol. Of the previously mentioned forms of estrogen, estradiol is the most common form of estrogen hormone for hormone replacement therapy (HRT) in the treatment of symptoms of menopause.
Estrogen referred as class hormone: E1 E2 E3
Estrone (E1) is the primary form of estrogen that your body makes after menopause. Estradiol (E2) is the primary form of estrogen in your body during your reproductive years. It's the most potent form of estrogen. Estriol (E3) is the primary form of estrogen during pregnancy.
Estrogens utility
Estrogen is a steroid hormone, often associated with the female reproductive organs, responsible for developing female sexual characteristics, but not only. Male body needs estrogen to function properly.
Estrogens play a role in almost all aspects of energy homeostasis and metabolism. DOI: 10.1210/er.2012-1055
https://doi.org/10.1016/j.biopha.2022.113808
Quoting Natureman:
Estrogen is a stress hormone. “You need stress hormones to develop, thrive and survive”.
The problem is when there is an excess and unregulated situation (by enough progesterone). When it lasts too long (often repetitive). Too much or too little estrogen can cause health problems in all people, including men.
Testosterone in the presence of aromatase enzyme
Testosterone can be converted into estradiol using the enzyme aromatase. Estradiol is used by the male body for:
• regulating sex drive
• achieving erections
• producing sperm
• testicular function
Estrogen also has other functions in the human body. It can help control cholesterol levels and maintain bone and heart health. It also affects mood, skin, and other tissues of the body.
https://www.medicalnewstoday.com/articles/estrogen-in-men?c=43533153689
Aromatase activity in RA
Pro-inflammatory cytokines stimulate aromatase activity. A hormone involved in aromatase activity is vitamin D, which downregulates aromatase in human RA macrophages.
Note: RA = rheumatoid arthritis.
Sex hormones play an active role in inflammatory responses, with androgens being anti-inflammatory, whereas estrogens have both pro- and anti-inflammatory effects.
DOI: 10.1111/nyas.12398

@MarkusAllenUSA said in Open-label trials - how is this allowed?:

"blinding" might not be feasible or ethical.

Not all studies can be "double-blind" or do not interest the pharma industries.
For instance about the impact the way of life, the food choices, the quantity of lethal rubbish substance, etc.
=> Always read the conditions of the studies: how long (rarely more than 12 months), with kind of stuff (chaw food or natural), arbitrary limited (only few ingredients, no variety, synthetic or not, etc.)

• read the body of the study, if different of the conclusion to please pharma funds...

@Mauritio said in Bile can serve as a reservoir for funghi, making them harder to treat:

Essential oils like thyme oil/thymol are fat soluble .
As per the posts above we need small, water soluble molecules .

What about dissolving the mix EO in alcohol before adding the "solution" in water, and last olive oil in the shake.?
Essential oils are miscible in alcohol. Then we mix EO and alcohol in water. Miscible too.

What about a water simili-fast of 4-5 days with a shake in which there is anti-fungal essential oil (EO).
Need some olive oil to avoid bile stasis in the duct.
These EO have to reach the second part of the colon.
Not a real fast as you provide basic trace elements (Mg, K, Na). We have to remain under 40-50 gr carbs if we wants to enhance lipolysis. Not obliged to do so but it’s easier in order not to feel hungry when taking some carbs. Sugar calls for sugar. An apple or an orange is OK.
Need fibers to lest LPS toxins and avoid constipation. Need some probiotics too, after the cure.

Useful link (in French, translator needed)
https://mirzoune-ciboulette.forumactif.org/t2000-boisson-he-effets-recherches#29307
Objectives with the EO drink
Fluidify – Bring stale fuel in the circuit– Assist the MMC – Target all areas of the body – Amplify the effects – Adopt a diet including interesting bases and nutrients – Adequate fluid intake.
Note:

1. Intended to reach the strains remaining under the radar, hidden behind a biofilm.
2. We don't deprive the strains of food, we ration them, and then we trap them. This will not kill them but will weaken their ability to resist. The immune system will be able to finish the job.
3. Importance of butyrate for the microbiome and tight junction health.
   => akkermansia muciniphila (=> food for bacteria producing butyrate + SCFA)
   Followed by ProBiota HistaminX from SeekingHealh ***
4. Magnesium helps to retain calcium and vitamin D and balance out potassium and sodium. I think magnesium is the most important mineral to supplement with if you are not eating a lot of vegetables or fruit.”
   Commentaires from Haidut:
   “Magnesium is only retained if there is sufficient ATP synthesis as magnesium is bound to ATP most of the time. However, in order to produce ATP properly, sufficient calcium is needed. So, maybe eat dairy and well-cooked leaves since this way you get both minerals?”
   Magnesium modulates parathyroid hormone secretion and upregulates parathyroid receptor expression at moderately low calcium concentration
   doi: 10.1093/ndt/gft400 2013

Edit: I've cured a histamine intolerance and a possible SIBO/SIFO with delayed caps of Essential oils. EO but not only.

@Uncover said in What supplenents should I take as a 16-yo boy:

Ray Peat did not promote the general "Eat vegetables" saying that is drilled into our brains by society on a ridiculous level.

Where have you seen I've advised to take vegetables as basic foodstuff.

• My last breakfast was composed of 3 kinds of fruits (pear and clementine) + 100 g (3 oz) of blueberries with 150 g Greek yaourt and 2 tsp coconut sugar.
• My lunch was composed of 2 mashed potatoes, mixed with frozen spinach (or broccoli last week) with one egg (free range), one small onion lightly fried in coconut oil, and half a tbsp. raw butter. + 3 slices of duck breast (100 g).
  As spinach is rich in oxalate (660 mg for 100 gr), I took one galet 1000 mg citrate calcium (21 % Ca).
  At the evening meal, I'll take 2 doses potassium citrate (1.6 gr x 2) and 1 dose bisglycinate mg (2.5 gr) in a shake (---), one apple cooked in the pan with coconut oil and butter added at the end, 1 slice Gouda cheese, 2 wasa bread slices with butter and leek soup.
  Edit: In my shake, I'l add some collagen since the amount of protein is weak.