150 mcg, upwards towards 250 mcg 10-15 days later.
Now back to 150 mcg twice a week.
But when there is infection, I increase the frequency to every 2 days.
But before taking a kelp tablet (titled), you'd better improve selenium intake to protect thyroid gland. 100 mcg. Not only in case of Hashimoto.
Several studies have shown that supplementing with selenium reduces thyroid peroxidase antibodies (TPO) and the severity of hypothyroidism symptoms (not recognized / not well measured when you're borderline).
Not only when TPO-antibodies are present but also because selenium has a synergistic relationship with iodine.
And please, don't take Amazonia nuts on a regular basis to get Se.
Posts made by LucH
-
RE: How much iodine do you take?
-
RE: Advice on lowering endotoxin
@Insomniac said in Advice on lowering endotoxin:
This double-blind, randomized crossover trial demonstrated that a single meal high in saturated fat can impede attention
Attention: The conclusion is different from facts.
Excerpt:
In adjusted models, women had more difficulty distinguishing target stimuli from distractors after consuming the high-saturated-fat meal than they did after the oleic-sunflower-oil meal (B = 4.44, SE = 1.88, P = 0.02).
Context:
Endotoxemy is present before ingesting 2 kinds of fats.
My reading:
The end-conclusion of the study is not the same as the elements of the study:
The study says:
Saturated-fat intake individually and jointly [negatively] influence attention [among the sujects].
My comment:
In terms of conveyor, SFA is very poor. The level of capacity to carry away is proportionally higher when the fat is unsaturated.
=> If you want a transporter take oleic sunflower. Mind this point: oleic sunflower is 85 % MUFA and is poor in PUFA. Not the same kind as usual sunflower oil. Not all oleic sunflower oils have the same compo.
Note: The take away would have been still more important with omega-3. Not necessary but this is relevant in the event of a crisis. Good to know. -
RE: Advice on lowering endotoxin
@Insomniac said in Advice on lowering endotoxin:
I have mixed feeling about monos but they do seem to be less likely to increase endotoxin absorption from the gut than saturated fats.
I haven't the same analyze. Partly true however if ... See details beneath.
How to manage with LPS endotoxins
Cascara tea + carrot salad with organic cider vinegar and 1 tbsp of olive oil. The Cascara if you have transit problems. Otherwise, carrot salad alone is sufficient.
Process: Cascara sagrada is mainly used to treat constipation. The anthraquinones contained in the bark inhibit the absorption of water and electrolytes in the intestines. As a result, the volume of the stool increases as it absorbs excess water, which increases the pressure in the intestine. This stimulates muscle contractions in the colon (peristalsis), which speeds up emptying of the intestine.To what extent are these elements relevant to facilitating the elimination of LPS endotoxins after taking antibiotics or chemotherapy?
- Glycine (homemade bone broth): Glycine attenuates the increase in LPS caused by the concentration of intracellular Ca and moderates TNF-Alpha in liver kupffer cells (glycine-gated chloride channel).
- Vitamin E (mix tocotrienols and tocopherols)
Source: Attenuation of lipopolysaccharide (LPS)-induced cytotoxicity by tocopherols and tocotrienols. Keiko Nishio et al. Redox Biol. 2013
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016328/ - Vitamin D is an antagonist of endotoxins (LPS / TLR4)
The expression of TLR4, NF-κB, and TNF-α was downregulated by 1,25(OH)2D3 in a dose-dependent manner.
Source : https://raypeatforum.com/community/threads/vitamin-d-is-endotoxin-lps-tlr4-antagonist-may-treat-lps-linked-conditions.12060/ - Orange juice: 100 ml of fresh orange juice at breakfast. => Interesting contribution of Ca and Mg and vitamin C.
Source:
Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression.Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression. - Supply of fatty acids to carry endotoxins
Sources:
Effect of Dietary Lipids on Endotoxemia Influences Postprandial Inflammatory Response. Journal of Agricultural and Food Chemistry, 65(35), 7756–7763 |
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b01909
Effets protecteurs du cholestérol sur les endotoxines - Note: Increased production of LPS residue after taking antibiotics or Phage Complete.
Avoid eating fatty foods during the attack phase.
A diet high in fat can make it easier for LPS to pass through the intestinal wall. Certain fatty acids actually serve as conveyors, especially the most unsaturated ones. In the event of a significant die-off, it will be advisable to take the antibiotic (or another viricidal substance) away from the meal. Therefore an inter-digestive intake is recommended.
-
RE: Advice on lowering endotoxin
Haidut has posted about useful nutrients. Find back in my "wallet".
Vitamin A reduces the half-life of endotoxin by a half: Acute effects of vitamin A on the kinetics of endotoxin in conscious rabbitsSince B1 is required for cell fuel and brain function, Thiamine and magnesium should be taken to heal gut inflammation if you want some left for the brain.
Note: Not a B50 (an inadequate level of B1 taking every day could overexcite cell growth).Vitamin B2 (riboflavin) Is Endotoxin (LPS / TLR4) Antagonist
https://raypeatforum.com/community/threads/vitamin-b2-riboflavin-is-endotoxin-lps-tlr4-antagonist.12061/
This is just a follow up on the recent post on both riboflavin and vitamin D.
Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections
https://raypeatforum.com/community/...gonist-may-treat-lps-linked-conditions.12060/Endotoxin (TLR4) antagonists are very beneficial substances and the more we have in our arsenal the more opportunity for successfully treating inflammation-related conditions.
Immunomodulatory effect of riboflavin deficiency and enrichment - reversible pathological response versus silencing of inflammatory activation. - PubMed - NCBI
http://www.ncbi.nlm.nih.gov/pubmed/26769828 -
RE: Advice on lowering endotoxin
@GreekDemiGod said in Advice on lowering endotoxin:
Shouldn’t the goal be not lowering endotoxin, but healing the gut lining, so that endotoxin doesn’t pass into circulation anymore?
Chatgpt sits besides.
Of course, gut lining must be fine. Need glutamine 1/4 tsp in a shake. 2x/d. Not if dysbiosis (candida albicans can feed with).
Edit: Chatgpt is right but only when taking a LPS killer, like EO or antibio. Not at the same time fat + killer. Not during 30' after ingesting food. Wait until food goes out of the stomach into the first part of the colon. See beneath (other post).
End of the edition.LPS is going to overload the liver. It's going to turn around in the blood circulation if not neutralized or captured towards the feces. Not a good idea to wait to see if the immune system is going to react.
-
RE: Advice on lowering endotoxin
@Insomniac said in Advice on lowering endotoxin:
I've read soaking could help a little.
Yes, specially for almonds.
-
RE: Advice on lowering endotoxin
@Insomniac said in Advice on lowering endotoxin:
Well I think that's manageable.
Yes indeed
It also depends how you combine with the rest of your meals and if you're susceptible to make stones. We can manage 50 mg oxalates.
On the figure:
H = Histamine
P = Phytate
Ox = oxalate
S = salicylate
Ox1-3 shows the level.
See the nota in the column "oxalates".Excretion level
The normal level of urinary excretion of Oxalate is less than 50 milligrams per day (mg/day). But most people consume between 200 and 300 milligrams of oxalates per day.
How much oxalate is too much? (In French, translator needed)
How to help excreting and neutralizing oxalates
https://mirzoune-ciboulette.forumactif.org/t1959-impact-negatif-de-loxalate-sur-le-metabolisme-chaos-biochimique#28285
See table if you prefer a picture. -
RE: Advice on lowering endotoxin
@Insomniac said in Advice on lowering endotoxin:
Why limit macadamia nuts to 1 oz? I couldn't find any issues with them at all.
Well, macadia has a good profile but is still marked Ox1 (44 mg oxalate) and Sal1 (Salicylate) in my table. For 100 gr (3.5 Oz.)
We can manage this amount of oxalates if we get some Ca from other food (to get rid of, in a kind of soap through feces).I come back with a table.
-
RE: Unexplainable and Reoccurring Nuisance
Hi,
Could you give more details about your thyroid measures and temps.
How do you digest?
Liver functions. -
RE: Advice on lowering endotoxin
@RawGoatMilk88 said in Advice on lowering endotoxin:
What natural antibiotics have you used with success for lowering your LPS load?
Hi,
First, you have to accompany LPS towards the gateway with oil:
If overgrowth, do not use coconut oil (viricide) until control.
MUFA is adviced: olive oil, avocado (not every day), macadamia nuts (1 oz. max). Vary.
If you can get a well-balance source, with moderate PUFA, it's still better, like in white fish, enhanced omega-3 eggs / butter, free range meat. Vary to avoid counter effects.
PUFAs convoy LPS on the best way but are not really "safe" because too often present in unappropriated quantity, as you know.
When killing the bacteria with e.g. essential oil softgels (EO) or antibiotics, a product to amalgamate the residues would be appropriate to avoid overloading (neutralization).
Note you have to make staples to recover energy and reload nutrients. +/ every 3 weeks, for 2 weeks. Adapt according to your feeling. Mind long period detox without varying the product used.
Clay or charcoal for example are useful. Or a salad of grated carrots with olive oil, once a day.
I've used 4 kinds of EO softgels prepared/ used in special way:- oregano + ---
- mint + ---
- lemon (liver)
- mountain savory + --- (liver)
-
RE: How to stabilize blood sugar during COVID illness?
Selenium and lung inflammation
You could give a try with selenium, as Dr. Klinghardt stated in an old interview. But only with a nebulizer, not with a spray. Device to be found in a pharmacies.
Note: Proposed for people suffering from asthma.
Two ampoules of liquid selenium (2 mg), twice a day (morning and in the evening)
Labcatal selenium 2 mg, in nebulizer.
Selenium gives miracles on asthma; 3 weeks delay anyway. But it hasn't worked for everyone (feedback from my forum readers) when the pathogen/intruder remains in place. -
RE: Peaty explanation of eating disorders
@Sugarnotsnow said in Peaty explanation of eating disorders:
What would be an explanation for it that alligns with his beliefs
Hi,
I made a search with Lucky's pendulum
Here is a clue (in 50 % of the cases).-
Mood disorder induced by low levels of progesterone affects weight loss or gain.
The fault may lie in enzymes that convert progesterone into allo, leading to lower levels of the metabolite, which adversely impact on mood disorders.
+ Low level of thyroid hormones
Source:
https://www.genengnews.com/topics/drug-discovery/both-obese-and-anorexic-women-suffer-low-levels-of-mood-enhancing-hormone/ -
Women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, according to new research published in the journal Neuropsychopharmacology.
https://www.sciencedaily.com/releases/2017/11/171110164029.htm
Note: This question remains: Which one comes first: Low levels of hormones in neurotransmission due to a lack or an excess of nutrients (or a pathology), or a hormonal unbalance, probably due to irregular metabolism of the thyroid.
-
-
RE: Oregano Oil as an antimicrobial
@Sugarnotsnow said in Oregano Oil as an antimicrobial:
-2 drops of oregano oil diluted in water or a carrier oil daily can reduce gut infections and improve digestion. Studies show that oregano oil reduced symptoms of gut dysbiosis, such as bloating and gas, by 40% over a 6-week period.
Well seen
Oregano to help digestion?
Some could misinterpret the situation and use oregano as a means to tolerate contraindicated foods, which are poorly metabolized and therefore force tolerance...
Well, oregano is very effective and powerful to dampen bacterial overgrowth, like in dysbiosis.
But if you take it to optimize digestion on a regular mode, in order to counteract side-effects of insufficient assimilation, you’ll get an unbalanced microbiota. Nature hates emptiness. Moreover not all phyla will be eradicated, even if oregano essential oil is very powerful as proofed in studies.
I’ve personally used softgels of 3 kinds, among which oregano, mint, mountain savory and Ceylon cinnamon + fennel and ginger to deal with fermentation dysbiosis and a supposed SIBO/SIFO. Softgels should be enteric coated (or use a suppository prepared in pharmacy, 50 mg if dysbiosis). We want to avoid alteration and the aggressiveness of the stomach walls
But whatever you make, some bacteria are able to hide down behind a film and a tiny amount will survive because of quorum sensing: targeted bacteria will transmit the information to other bacteria to make them genetically evolved and get the capacity to survive to a new environment.
So, the tactic should be the next one:
I prepare the ground and I reserve the use of essential oils for a crisis situation, not to accommodate and tolerate what alters the metabolism.
I ration, I weaken then I bludgeon the intruders who do not live in symbiosis.
It does happen in a cycle; it's temporary. And of course I then take the place with a course of probiotics. I'm not waiting for nature to take its course again because it will be a lottery if you try it with yogurt, kimchi, kefir or kombucha. -
RE: How to stabilize blood sugar during COVID illness?
@RPadmirateur said in How to stabilize blood sugar during COVID illness?:
it seems that not assimilating enough sugar during times of stress, (current COVID infection), is what raises my b.p. Also, I know from experience that starches are completely OUT when I am under stress...I simply cannot digest them.
First for covid:
Vit K2 (with D3 if moderate dose, otherwise seperated if 5 000 UI D3).
Vit E (2 tocols minimimum) : 3 x/wk 400 UI (Now Foods Gamma)
CO2 (bag breathe or a mix with baking soda => See Yerrag.
Zinc 30 mg.For the stress:
bisglycinate magnesium 300 mg 3x/d.
Breath exercice (sophrology) or EFT (Emotional freedom technique).
WalkingFor carbs
If your digestion is not optimal take a supplement enzymes.
But the pH for starch (potato, rice, wheat, cakes) is quite different from proteins.
If there is more than 125 ml liquid, it's going to be much more difficult to obtain the right acidity for assimilating proteins.
Moreover we have an amount lactase enzyme limited (milk lactose). Variable (...).
For glycemia, the most important meal is the breakfast: Impact on the whole day as far as insulin spike is concerned.
Your menu is well balanced as far as Ca and P are concerned, thanks to milk.
Hard cheese is high in phosphorus but milk has a good ratio (1 / 2.2 for P / Ca). => Compensation.
If too far from the ideal ratio, it's a source of stress (PTH).
If bloating, I'd make smaller meals. 1/3 carbs and 2/3 proteins. Or the contrary. We call that weak protein when 1/3.
Or you eat every 2H30 - 3H00 on a different model. No protein when you eat starch.
You have to find the easiest way by successive tries.
When eating proteins at the evening meal, I'd take betaine HCL to optimize the acidity required for proteins. Once a day. No need at midday.
=> I take Doctor's Best - betaine HCL, with pepsine and gentian bitters. 120 caps. -
RE: Vitamin K and constipation
@sphagnum said in Vitamin K and constipation:
what is considered to be a high dose of K?
High dose Vit K can interfere with Vit E
They are all fat-soluble vitamins and can compete with each other for absorption into the micelle. Vitamins A and E are antagonists of vitamin K because they interfere with its absorption and metabolism.
Taking a high dose Vit K2 requires transporters that are in limited amount for transport in circulating lipoproteins for subsequent uptake by tissues.
How much is too much is not clearly defined.
By the way excess Vit E, K and Q10 leaves quinones but our liver has a limited capacity to deal with.
I never take Vit A supplement at the same time as the other lipovitamins. -
RE: whats your opinion on taking kefir?
@the-MOUSE said in whats your opinion on taking kefir?:
i think main is diverse microbiome. also as age, microbiome changes, maybe maintaining biome diversity of that of some1 young could be beneficial
Yes, older people (> 70 y) have a weaker microbiome.
*) Quorum sensing
In short: Capacity of bacteria to communicate to share information in order to coordinate one or several actions.
Quorum sensing bacteria produce and release chemical signal molecules called auto-inducers that increase in concentration in order to obtain a function from host cells. Expressed differently, if some bacteria come predominant they may take the control of what you want to eat. In some circumstances (same kinds of foodstuff, without a variety from macronutrients and vegetables), they overgrow and take the control of other bacteria. It’s no longer a community with more or less the same rights to exist, but slavery (exploitation of the weakest ones to the profit of the strongest ones from the new association).Impact of the microbiome
*) Key ideas from part 1
• 80% of our immunity depends on interaction with intestinal bacteria.
• Bacteria live in symbiosis with the host as long as a species – a phylum – does not seek to extend its range…
• The two dominant phyla are Bacteroides and Firmicutes. They produce beneficial SCFAs, mainly from polysaccharides derived from indigestible fiber.
SCFA = Short-Chain Fatty Acids
• A diet with or without fiber, in an appropriate quantity (20 – 30 g), will direct the dominant type of bacteria.
*) Key ideas from part 2
• The Firmicutes / Bacteroides (F/B) ratio is oriented by our dietary habits but Firmicutes can be dominant following maternal transmission.
• Species diversity is important.
• Some studies do not always demonstrate a cause and effect relationship between the F/B ratio. But this relationship is indeed associated with obesity, and, consequently, with metabolic comorbidity (death).*) Key ideas from part 3
• The type of microbiota affects nutrient acquisition (assimilation), energy recovery (calories extracted) and host metabolic pathways (hormones and immunity).
• If you disrupt the microbiome on a regular basis, you disrupt harmony and trigger a deleterious process: low-grade inflammation, dysbiosis and leaky gut at the end of the race.
• The stomach and each section of the intestine are colonized by a different type of bacteria, at different concentrations, with a different ecology.
• Overweight or obese people have a different Bacteroidetes / Firmicutes ratio. More Firmicutes.
• If you eat foods that are high in sugar or can easily be converted to sugar, these foods will feed firmicutes. While complex carbohydrates and insoluble fibers rather feed the Bacteroidetes.
• The type of bacteria influences your insulin reaction and your desire for a type of food (fatty, meaty or sweet), and therefore your weight gain or not, by 10 to 20%, for the same calorie intake.
• If you have a low F/B ratio (few bacteria) you will often have cravings. In addition, Firmicutes extract more calories from food. Faster weight gain (visceral fat).
• If you practice intermittent fasting (for example 16/8 or 5.2), this stimulates certain metabolic pathways (repair, muscle growth, energy use).
• If you want to create a deficit, you must do it in a moderate manner, so as not to stress the brain and the microbiota. 10% below metabolic requirements (BMI). It will also be effective if you practice this system 5 days a week, to maintain a friendly family life (family meals).
• 50% of healthy people report an endotoxic reaction (LPS) when they ingest a McDonald's meal or a frozen pizza. This means that we are not all equal when it comes to genetic susceptibility (genetic predisposition to disease). But we can reorient the environmental factors that have a primary influence on the composition of the terrain.
• When a teenager eats McDonald's or a pizza with a cola or a beer, regularly, he configures his microbiome (reoriented balance) and is conditioned for a type of response (attraction to certain foods).
• If you take a certain type of probiotics and change your diet (fiber, fruits and vegetables) and lifestyle, you can act to prevent leaky gut. To do this, we must eliminate obesity from the equation.
• Excess weight leads to hormonal dysfunction, disrupted metabolism, and then low-grade inflammation. This will result in dysbiosis (fermentation). If this continues, it will turn into leaky gut, leading to clogging and a continued disruption of homeostasis. In general, this induces/results in a reaction of the immune system (clogging, elimination and/or immune pathology).
• Researchers postulate that low-grade inflammation comes first, before dysbiosis. Then obesity appeared. But this pattern is not recurring/fixed. On the other hand, obesity will certainly induce low-grade inflammation via hormonal changes. This then leaves the door open to a whole bunch of metabolic pathologies.
• Short-chain fatty acids (SCFA) are produced mainly from resistant starches and polysaccharides, thanks to the action of certain bacteria. We need SCFAs and CLA to produce certain hormones important for intestinal barrier integrity.
• Short-chain fatty acids play an important role in the proliferation of macrophages in all tissues of your body. They are very important for the immune system and, of course, your metabolic system.
• If you do not tolerate prebiotics well (fragile intestines), or if your immune system is over-reactive, there are sporebiotics. These are spores arising from the cell wall of bacillus spores.
https://youtu.be/1fgf39-tBcg 3’28’’ (Dr Mercola is interviewing Dr. Dietrich Klinghardt)*)See Impact of the microbiome (3 parts) (In French, translator needed if you want details).
http://mirzoune-ciboulette.forumactif.org/t1589-impact-du-microbiome#18869
=> Supply required. -
RE: whats your opinion on taking kefir?
@the-MOUSE said in whats your opinion on taking kefir?:
@LucH thanks. @yerrag @mostlylurking any additonal opinion on this?
Right. Well done but not enough as explained. Make breaks.
Or wait until the problem comes if you prefer. Not sure about the time it'll take. Have you ever heard of quorum sensing in the microbiome? -
RE: Sudden lactose intolerance, need help.
@yamnayan said in Sudden lactose intolerance, need help.:
Could this be from a sudden increase in sugar? I did sugarmaxx like a retard. I have a feeling that I might have nuked my metabolism drinking a shit ton of diet coke before discovering peat. Replaced that with normal refined sugar and a coke here and there. Will look into that as well.
yes, but you have to understand this point:
- Too much / too frequent of one thing is going to impact the kind of predominant bacteria. So, what was well balanced is going to change.
- excess refined sugar is going to deplete thiamin. Interaction between B1 B2 B3 and B8. Brown sugar cane is a misfit. Not really complete. Muscovado is better but the taste is different. I Have 3 kinds of sugar at home:
=> muscovado, coconut sugar, brown cane sugar.
- occasionally sugar beet (white sugar) for pastry / cakes, and pure Via (a mix with stevia and erythritol). Note that all polyols have a bad impact on microflora and help fermentation if repeated use. But this one is the least negative.
- if you eat manufactured food (not the whole element found in nature, completely processed), you eat on a devitalized way. Lacks are repeated.
Note: Don't take a B50 supplement on a regular basis. Not the right posology: cancer growth stimulation). RDI or uptake above 90 mg B1 HCL. I take 100 mg B1. Need to be developed elsewhere. - Diet coke contains edulcorates. Impact on the microbiota. Like every kind of drink with edulcorates.
- When taking repeatedly the same foodstuff, you must know / study the possible side effects.
Suggestion:
Use collagen powder for half of your protein if you have problem, if you can't manage with bone broth.
Too often eggs could give an immune response. OK for 2 or 3 times 2 eggs.
You could mix lentils or peas with rice to get a full spectrum of amino acids.
-
RE: Vitamin D extends youthful thinking
I decode:
- 2.6 and 1.3 year benefit (with 2 kinds of measure).
- DNAmAA did not statistically differ between participants.
- Therefore we concluded vitamin D supplement is associated with lower DNAmAA with vitamin D deficiency.
My reading:
How the hell can they say 2 different things in the conclusion! (no statistically difference and lower methylation of DNA).
A clue: The sponsors of the study are also the financiers. They will only read the conclusion.
-
RE: How to stabilize blood sugar during COVID illness?
Blood sugar and carbohydrate absorption speed
Source: Montignac > blood sugar > Physiology of intestinal absorption
Not all carbohydrates are absorbed in the same way: 400 K/cal. of lentils is not equivalent to 400 K/cal of potatoes. For the same amount of carbohydrate, consuming lentils provides three times fewer available “calories”.
Figure 1: Carbs absorption speed (with food stuffs)
Credit : http://www.montignac.com/fr/sucres-lents-sucres-rapides/There is no slow or fast sugar. This is a misconception!
Figure2: Carbs absorption speed (with sugar types)
Green spot: disaccharide (sugar cane, honey)
---: Polysaccharide: starch
==: (blue spot): monosaccharide (glucose & fructose)
Note: Milk and yoghurt are special cases (growth homone).Useful link (in French, excerpts from the book) (with pictures to illustrate the comments)
Book : Glucose Révolution – Jessie INCHAUSPÉ
https://mirzoune-ciboulette.forumactif.org/t1925-glucose-revolution#26942- “food order and postprandial changes”: The ideal order of foods: fiber – proteins (with fat) – carbohydrates. The fibers ingested first considerably reduce the glucose peak caused by sugar.
- Learn how to smooth the blood sugar curve, with examples. This way you can better manage possible weight gain or lost energy capacity.