Posts made by wrl

Here's some diet clues to help reduce the histamine load that the body has to deal with/metabolise. I think major sources of histamine are hard (matured) cheeses, seafood, fermented foods (eg sauerkraut) and some vegetables (eg spinach, tomatoes).

https://www.mastzellaktivierung.info/de/downloads.html#lebensmittelliste

This could be due (in part) to magnesiums pharmacological effects, particularly blocking glutamate (NMDA antagonism). This has some positive effects on the dopamine system (the "D2" receptor), alongside general relief from excess glutamate (excitotoxicity).

Archived page of a fresh post with an pro-A stance.
How long will it stay up for‽

(Archived rpf webpage)
https://archive.ph/j900l

Screenshots of post excerpts...

@Kvirion
Yup true; ok, then mix some S.bicarbonate into the mix to neutralise any free phosphoric acid.

@ah said in The Dental Care Thread:

some of the inactive ingredients arent great (titanium dioxide, guar gum)

Seems it also contains some phosphoric acid!
Maybe a sodium bicarbonate swish after using this product?

@yerrag said in Microcrystalline Cellulose in supplements:

I think it is an energy sink that gets our body to waste its energy on an endless cycle of expending energy to futilely trying to get rid of the toxins.

Agreed.
Thank you for sharing your perspective.

I'm wondering what the risk/danger/impact is of ingesting microcrystalline cellulose contained in supplements. The amount may indeed be very small...
I've read the posts on rpf - RP says adsorption is an issue. For someone with leaky gut/SIBO/gut motility issues, could the microcrystalline cellulose potentially be more of an issue?

I've searched extensively but haven't found any of the desired products without this excipient.

"Its presence in food, like that of the polyester imitation fat, microcrystalline cellulose, and many other polymers used to stabilize emulsions or to increase smoothness, is often justified by the doctrine that these molecules are too large to be absorbed. There are two points that are deliberately ignored by the food-safety regulators, 1) these materials can interact dangerously with intestinal bacteria, and 2) they can be absorbed, in the process called "persorption."" — Ray Peat, PhD

Pathologe 1993 Sep;14(5):247-252 [Persorption of microparticles]. Volkheimer G “Solid, hard microparticles, such as starch granules, pollen, cellulose particles, fibres and crystals, whose diameters are well into the micrometre range, are incorporated regularly and in considerable numbers from the digestive tract. Motor factors play an important part in the paracellular penetration of the epithelial cell layer. From the subepithelial region the microparticles are transported away via lymph and blood vessels. They can be detected in body fluids using simple methods: only a few minutes after oral administration they can be found in the peripheral blood-stream. We observed their passage into urine, bile, cerebrospinal fluid, the alveolar lumen, the peritoneal cavity, breast milk, and transplacentally into the fetal blood-stream. Since persorbed microparticles can embolise small vessels, this touches on microangiological problems, especially in the region of the CNS. The long-term deposit of embolising microparticles which consist of potential allergens or contaminants, or which are carriers of contaminants, is of immunological and environmental-technical importance. Numerous ready-made foodstuffs contain large quantities of microparticles capable of persorption.”

@yerrag
I would value your opinion on this!

@Appa said in Dexamphetamine withdrawal:

The best way to reset stimulant tolerance is through NMDA antagonism.

Magnesium is an NMDA antagonist.
An epsom salt foot bath or Mg supplement can work.
Amantadine is a powerful NMDA antagonist as well as having multiple other properties (inc dopamine "receptor activation" at D2).

NMDA antagonists can "take the edge off" excitotoxicity and help to reset neurotransmitter patterns/systems aka habits.