@lucasmenem said in Cerebral thiamine, what you know?: excellent information, thank you very much You're welcome. I'm glad to try to help by sharing info about my own health journey. I've posted more info about thiamine recently on this thread

@shedim I can't breathe when

@fd It is possible for sure but probably unlikely with doses lower than 5mg a day

@PissBoy It's about restricting the activation of the cholinergic system by protecting yourself against patterns of learned helplessness. You could try and visualise sodomising your school's faculty. Ray and Georgi talked about this. The dark side of stress (learned helplessness) - Ray Peat Intelligence and metabolism - Ray Peat How do you know? Students, patients, and discovery - Ray Peat

@Cearrson Hi, I suggest that the positions in which you instinctively sleep are potentially better in many cases, sleeping on your back is not better in itself, I have observed several people who snore and have sleep apnea on their backs, and when I suggested that they sleep on their sides and / or reduce their number of pillows and they instinctively began to sleep more on their sides, they no longer snored and no longer had sleep apnea

@PissBoy I was starving all the time, but I also drank insane amounts of coffee which worked as an appetite suppressant.

@skylark yes I have talked about this before with my friends and family (another sound that I dislike very much is styrofoam, though not as much as Velcro, which even thinking about it now makes me wince in pain) — and the only person who gets me is a close friend of mine who told me that he hates the sound of metal grating on metal and told me that his dad and brother share similar things, and he said something about overstimulation and autism, which runs in his family.

Sounds like re-peat. Which is really what most have been doing. Just ray-peating everything he said. Names matter. Literally. It’s part of the key to understanding our reality.

@yeezy both sound good. Experiment!

@HoldenCox I take it sublingual

@hypermensch I had this for many years, it's something that got solved over a long period of time, so it could have to do with a variety of factors, but I woul say the main way to go about relieving it quickly would be lowering endotoxin (DAILY carrot salad, limitation of starch consumption), increasing calcium, and using beneficial things like aspirin and progesterone.

When you’re cutting, either from restricting calories or preferably by raising the metabolic rate, you’re going to have less energy in the system and most facets of health will suffer. Focus on lowering stress and increasing youth-promoting hormones like thyroid, progesterone, pregnenolone, DHEA before and during the cut. A clean bulking phase followed by a shorter cutting phase serves well to bolster nutritional stores prior to the cut. In the cut, I would increase ratio of carbohydrates to protein slightly and prioritise gelatinous sources of protein over muscle meats. I would also focus more so in concentric loading of muscles during training. This is to lower inflammation while maintaining muscle mass during the cut.

50-100mg pregnenolone with 400 IU Vitamin E. I have unusually low temp usually but if I take this, my wife starts asking me whether I'm sick or have a fever. It's very effective.

The Wim Hoff cold plunge training guys are saying the health benefits are because of the adrenochrome produced. True?

@A-Former-User said in How to lower Adrenaline: I remember from the RP Forum that you're a huge fan of thiamine and convinced that thiamine deficiency is behind most people's problems. I'm not so sure about that. The list of symptoms of thiamine deficiency is basically every symptom under the sun, and I know that Ray Peat was never terribly convinced that thiamine was the be all and end all. I asked him about it once and he said it's most likely hypothyroidism. He advocated for dosages between 10-100 mg a day. There is a very long list of people who believed they had beri beri and started taking high dose thiamine and experienced nothing but misery and a host of new problems, which I know the thiamine cheerleaders simply call "the paradoxical reaction" (or something to do with methylation or not having the right co-factors etc), but it never went away and they had to give up. They're in a facebook group and it's depressing reading. Do me a favour mate and PLEASE don't spam every thread on this new forum with the beri beri guff! I should just ignore you because you are being a first class jerk. But I've decided to respond instead. #1: Ray Peat recommended thiamine quite a lot actually; he just never wrote a full article about it. Here are a few links for your consideration: Thiamine mentioned in Ray Peat's written work Vitamin B1 (thiamine) mentioned in Ray Peat's written work Thiamine mentioned in Ray Peat's audio interviews Vitamin B1 (thiamine) mentioned in Ray Peat's audio interviews #2 This forum is named the Bioenergetic Forum for a reason. https://www.nature.com/subjects/bioenergetics "Bioenergetics is the branch of biochemistry that focuses on how cells transform energy, often by producing, storing or consuming adenosine triphosphate (ATP). Bioenergetic processes, such as cellular respiration or photosynthesis, are essential to most aspects of cellular metabolism, therefore to life itself." Ray Peat focused a lot on the concept that if cellular energy is optimized then health follows. It will probably come as a shock for you to learn that thiamine is required for cellular energy. Thiamine acts as a co-enzyme in several steps in the Krebs cycle which is how cellular energy (ATP) happens. The importance of thiamine (vitamin B1) in humans