@Mauritio said in Vitamin A quotes from Ray's favorite physiology book: @Peatly said in Vitamin A quotes from Ray's favorite physiology book: @Mauritio There are huge variations in results for vitamin A studies. I think Dr Peat’s recommendation, which is to be cautious if hypothyroid, seems reasonable. I would like to see that Iranian study replicated elsewhere – especially in regions where Billy Goat is blocking the sun. Yes, I agree. What does it have to do with the sun/ Vitamin D? I was under the impression that being exposed to sunlight, for extended periods, increases your vitamin A requirements. I was thinking that if the sun is being blocked this might lower need? Dr Peat talking about light exposure and vitamin A This is the dentist Dr Peat mentions in that clip Emanuel Cheraskin, M.D., D.M.D., late Professor of Oral Medicine at the University of Birmingham, AL. The "ideal" daily vitamin A intake Relationship of vitamin A and oral leukoplakia

@banquos-ghost I originally started taking NDT by the Life Giving Store, around four years ago. When I first started taking it, it worked for me but stopped working about a year after I started it (my TSH went up to 3.0 and I still had all of my hypo symptoms). What ended up working the best for me and what I take now is Cynomel (I break up one pill into four pieces and take it throughout the day with meals). Then starting around 6:00 PM, I take one drop of Tyromix. I take one drop of that every 1.5 hours until I go to bed. So, I end up taking 5 drops total of Tyromix (orally) and spread out. That amount of Tyromix is what helps me sleep throughout the entire night without waking up, and that is the marker that I use to decide the dosage of the Tyromix.

https://pubmed.ncbi.nlm.nih.gov/27565891/#affiliation-4 Agmatine is very peaty? I think Dr Peat mentioned agmatine somewhere? I'm currently dealing with rabid insomnia. I pray this helps.

@Amazoniac said in Vitamin C in the prevention of cellular respiration (CcO) inhibition by sulfide: 200 mg ascorbic acid per day Practical application: that's roughly the amount in 500ml of orange juice, less if it's fresh.

No wonder that we seem to be on a never ending decline when it comes to young people's mental health. What chance do kids have when before they're even born they are exposed to even more and more chemicals that mean they are more likely to be dumb and sick. One upside I guess is if you're aware of this and you and your partner don't eat PUFA you're going to have a child with an automatic leg up compared to everyone else.

@Buckian Ive had similar experiences. I now only use red light therapy before my last meal of the day and never after

This is not a new study. We have discussed this study several times. You can follow John himself on Twitter. He had a very interesting series of tweets when the study was published.

@sphenoid said in Vitamin A deficiency impairs gonadal steroid synthesis: [image: 1708376936556-screenshot-2024-02-18-085932-resized.png] The vitamin A movement could be a possible pop control psyop Disturbing! I'm not too concerned about the fertility of older people who go low A, but the young people and children who have to eat what their low A moms prepare. I sure hope this is reversible.

@kyrre yes pineapple is GOATED cos of the bromelain. Eating it after high protein meal may be great as it helps to break protein down

High sodium chloride intake decreases betaine-homocysteine S-methyltransferase expression in guinea pig liver and kidney "Betaine-homocysteine S-methyltransferase (BHMT) is the only enzyme known to catabolize betaine. In addition to being a substrate for BHMT, betaine also functions as an osmoprotectant that accumulates in the kidney medulla under conditions of high extracellular osmolarity. The mechanisms that regulate the partitioning of betaine between its use as a methyl donor and its accumulation as an osmoprotectant are not completely understood. The aim of this study was to determine whether BHMT expression is regulated by salt intake. This report shows that guinea pigs express BHMT in the liver, kidney, and pancreas and that the steady-state levels of BHMT mRNA in kidney and liver decrease 68% and 93% in guinea pigs consuming tap water containing high levels of salt compared with animals provided untreated tap water. The animals consuming the salt water also had ∼50% less BHMT activity in the liver and kidney, and steady-state protein levels decreased ∼30% in both organs. Pancreatic BHMT activity and protein levels were unaffected by the high salt treatment. The complex mechanisms involved in the downregulation of hepatic and renal BHMT expression in guinea pigs drinking salt water remain to be clarified, but the physiological significance of this downregulation may be to expedite the transport and accumulation of betaine into the kidney medulla under conditions of high extracellular osmolarity."

@Ecstatic_Hamster tried them a few years ago and never received it. Maybe I'll give it another shot. Thanks.

@haidut Fantastic research. And great presentation of the pathogenicity of estrogen, once again.

@haidut Great post, I wonder if clonidine could potentially be useful here.

@haidut So this isn’t something someone can run a test for? It’s crazy how close to useless blood tests are the more we learn of this stuff