What about so called progesterone positive cancers. I never bought the story of progesterone positive.

Cool to see that get through finally after decades of people talking about this . (& for its effect on teeth, my sensitivity went away when i stopped using toothpaste with this in it) Taurine gives protection against fluoride (if dont get along with it well at 500mg lower doses probably work well too, even <100mg is protective against mercury toxicity) and ~300mg GABA can reverse most of its impact on thyroid (lower dose works best) https://www.researchgate.net/publication/330609672_Analysis_of_the_protective_effects_of_g-aminobutyric_acid_during_fluoride-induced_hypothyroidism_in_male_Kunming_mice

I saw on rpf someone mentioned majority gamma is the main one to be aware to supplement for tobacco smokers.

do you think famotidine is superior to cyproheptadine to keep in the medicine cabinet?

@Butter-Girl meals high in meat , seafood, some wholegrains if eating for the fiber & nutrients e.g spelt (ray said some of his teeth decayed from a time where he was eating a lot of wheat germ for the nutrients without calcium)

@latin some animal growth plate never close some reason

Do you all think starch as opposed to just fruit and honey is important for growing children?

Wikipedia says milk is up to 3% trans fats. Where's that 2% figure from? I'm skeptical about the fat metabolism in general. It's unclear if harmful fats are excreted or metabolized.

@Gaston

5 Supplements To Inhibit IL-11 (animal studies) https://www.youtube.com/watch?v=nYbJj3uRn1I One of the comments on YouTube: Thx Richard for this interesting presentation.Actually it's not necessarily the curcumin but the other ingredients in turmeric that are responsible for the inhibition of IL-11. So the whole food is always more potent than any supplement. By the way piperlongumine also inhibits IL-11. I take them every day in my coffee and in meals combined with olive oil ,black pepper and ginger.

Makes sense when B1 is needed for mitochondrial respiration, but not the only one needed.

@haidut thank you

Just my simplified take on arthritis, as more and more I am swayed to think that there is only arthritis, and that arthritis is caused by low metabolism, and very much so because CO2 deficiency from low mitochondrial metabolism makes the ecf acidic, enough so that some salts, urate salts being one, precipitate, and cause the formation of crystals that cause wear and tear on our joints. I profess ignorance though, on the matter of the different forms of arthritis, as when I attempt to understand the different forms of arthritis, the explanations given in the literature always lead to draw blanks, which makes me either an embecile thet fails to comprehend or simply that the literature is just playing on words and terms that give different names to a banana. The added complexity is a ploy to distract from the one true cause of arthritis, if I may dare say so. Which is why Ray points to hypothyroid as the cause of arthritis, which I first thought of as a rather simplistic explanation. But if I can relate to cause and effect, and dig deeper into it, it is not as complicated as it appears to be. The key is acid base balance. As simple as that. When we have an abundance of CO2 because our body makes a lot of it at our disposal, we have the best pH buffer available for our lungs and kidneys to manage acid base balance. When alkaline, it can turn into an acid called carbonic acid, and when acidic, CO2 can turn into bicarbonate. This is based on Le Chatelier's principle, where the direction of a reaction is in the direction of the stress that it relieves. What better way to provide a surfeit of CO2 in our body than to be producing energy using mitochondrial oxidation. Vitamin B1 is a crucial link in a chain of nutrients and substances and processes that enable mitochondrial oxidation. Simply being deficient in one link makes rhe chain broken, and a broken chain only leads to low metabolism, and the resulting imbalance in pH, usually acidic, will just cause the formation of salt crystals that irritate and inflame and destroy tissues. I know enough how to monitor my acid base balance, so I know what remedial actions to take to keep my acid base balance from being chronically in an imbalanced state. Many bad things happen in a chronic state of acid base imbalance. I have high uric acid, yet I don't have any arthritis, much less gout. Only because my optimal acid base balance keeps uric acid crystals from forming. I don't have tachycardia (high heart rate) because my heart muscle pumps well and isn't strained because the muscle contracts and relaxes effortlessly because of good acid base balance. I don't fear cancer because I believe that an acidic ecf is what causes regulatory and harmless and commensal microbes to turn into virulent parasites that cause cancer to develop. Yes, vitamin B1 is important, but such studies are subordinate to putting all the pieces of rhe puzzle together to form a whole picture. This is where we need work on, as without this perspective one can end up taking one supplement after another and not progressing from his poor state of health.