Reversal of hair loss in Mice with “sugar gel”
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@engineer said in Reversal of hair loss in Mice with “sugar gel”:
Does this imply that those with a G6PD deficiency would have trouble with hair?
I would think so.
@engineer said in Reversal of hair loss in Mice with “sugar gel”:
Another question: Is this related to total glycolysis or only the part that actually gets oxidized?
I think it's more related to local glycolysis. Glycolisis is the physiological state of metabolism of the hair (and skin and wounds and other fast dividing tissues) .
I don't know how much systemic metabolism affects scalp metabolism.Dare to think.
My X:
x.com/Metabolicmonstr -
@Mauritio said in Reversal of hair loss in Mice with “sugar gel”:
I think it's more related to local glycolysis. Glycolisis is the physiological state of metabolism of the hair (and skin and wounds and other fast dividing tissues) .
This alone could turn out to be one of (if not) THE major risk factors for hair loss. Someone else mentioned it, but keto diets tend to be brutal to hair, likely because increased FAO > /\ FFAs > \/ glucose available to use.
So that would imply that to help stop hair loss or regrow it, all you'd need to do is increase glycolysis, which we know how to do.
Are there any studies on such a change actually delivering results?
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@engineer there was a guy on the rpf who had before and after pics of 7 months rubbing in topical progest-e.
Not that that exactly answers your question, but it at least is an example of pro-metabolic things helping hair metabolism as opposed to the common blood flow improvement methods. -
amazingly someone was talking about topical ribose 10 years ago
https://www.hairlosstalk.com/interact/threads/dermal-benefits-of-topical-d-ribose.69208/
and
and
https://immortalhair.forumotion.com/t11589-has-anyone-used-ribose?highlight=ribose
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I had a realisation
It is not sugar you need, but ATP, so things like Ribose would be better
I think some people confuse the two
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@wester130 someone quoted somewhere in here, that Ray said that the cells confuse pure ATP as leaking components from a damaged cell, and create an immune response, thus counterintuitive to use (I wonder if this is similar to how whole proteins induce a cytokine storm).
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@LetTheRedeemed what does this mean for people applying topical ATP precursors to their scalp?
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@wester130 Good q, it was implied that's bad, but I don't know beyond "immune response bad" is my assumption
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i think he meant direct ATP supplementation, I remember the quote, he said taking direct ATP was bad
the precursors like coq10, ribose, creatine, magnesium malate which covnert to atp look Okay.
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@wester130 oh wow so sorry I missed this, I thought you meant supplementation of ATP LOL.
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Some good anedotes online of people regrowing lots of hair using coq10 for extended periods.
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@Hearthfire topically?
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No, oral. Just regular coq10, 400mg.
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Will you be using ubiquinone? In my search to find if there is a pro-Peat consensus between the two versions, I see you mention about first using ubiquinol, but planned on switching to ubiquinone. Just curious of your take on it. I also see on that thread the mention of it being good for gum health. I used to use a toothpaste CoQ10 and used to have very good gums — per a dental check up after a 12 year absence. I think I'll attempt to kill two birds — hair and gums — with CoQ10.
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Yes, I switched back to ubiquinone. Someone here mentioned its the superior form, even though the "mainstream" opinion is that ubiquinol is. ubiquinone is also the form those anecdotes mentioned growing back significant amounts of hair.
I think I said elsewhere, but I had a ton of vellus hair growth while using it. Not sure if it s the coq10 or all the other things I'm doing. I believe it is contributing.
