Peaty uncoupler vs. Ozempic who wins ? New study.
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@CrumblingCookie I think those two things come down to the same conclusion.
Because if the fluoride atoms disassociated , should not that show up relatively quickly via systemic side effects, as in liver and kidney damage ? If not, how else do you suppose the damage would show up.In these 2 studies they looked at liver and kidney markers and found no significant difference.
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@Mauritio said:
I think those two things come down to the same conclusion.
Because if the fluoride atoms disassociated , should not that show up relatively quickly via systemic side effects, as in liver and kidney damage ?Not necessarily as I think of fluorine/fluoride harboring quite some insidious effects on endrocrine and exocrine glands. If there was huge fluorine unloading we could expect kidney damage. E.g. if all 22mg fluorine of 200mg BAM15 dissociated.
But if it's only 5% or 10% dissociation and therefore 1.1 or 2.2mg fluorine/fluoride per day it won't be obvious but very obfuscated in a range of unspecificity. Would then require larger daily amounts of iodide and support of renal excretion to counteract.
For comparison, amiodarone also has its two halogens (iodine, 37% w/w) attached to its aromatic ring so just as with BAM15 we would expect little dissocation. It's been shown however to yield c. 10% dissociation of iodine and any dose above the very-low-dose 100mg/d is therefore an established possible cause for blood--testis barrier disruption and inflammatory degradation of the interstitial testicular tissue in humans.
Well if anyone's worried about F in BAM15 then 2-3mg of daily KI wouldn't be the worst to stack with it or in general. -
If anybody from Europe is interested in a group buy of BAM15 from sigma audley, hit me up.
We're gonna buy 10g for 300$ and divide through 3 people.
(1 spot left)
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@Mauritio how do you get an account on sigma Aldrich? Thanks
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@Mauritio it’s a good vendor, they ship to a warehouse in Germany which gets reshipped to your address in Europe - so when the package goes through customs, it hasn’t got your name on it and there is virtually 0 risk of consequences of your package being detained. Also it’s very rare for these shipments to get seized from these vendors.
Best of luck with your experiment
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@BeamsOfEnergy no it's sigma AUDLEY . A Chinese steroid selling company.
Look at @alfredoolivas response above .
They have a decent reputation, but of course its not Amazon customer service, so stuff goes wrong.
Here's a 400+ pages long thread on them. With countless successful orders , but also some delays, stuff missing etc.
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@alfredoolivas thanks. Yes and don't they also have a warehouse in Germany directly ?
Not sure if they store BAM 15 there though .They seem as legit as it gets ,at least for company doing what they do lol.
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@Mauritio no warehouse in the EU as of now, only USA.
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@Mauritio
I'm interested. I live in the US but all my family is in The Netherlands. You could send it there and they can send it to me. -
@happyhanneke nice. Just send me message and we'll set it up.
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"This study indicates that BAM15 inhibits atherosclerosis through a multi-molecular mechanism, and we propose it as a novel anti-atherosclerotic drug."
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Science is slowly getting more peaty.
Combination of a thyroid receptor b agonist with BAM15 for fatty liver, showed superior results than each on their own. -
@Mauritio post ur before and after too
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@alfredoolivas lol they made their Chinese peptide company sound like sigma Aldrich