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    Methylene Blue

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    • CO3C
      CO3 @Tahodama
      last edited by

      @Tahodama specific thing that's in milk and cheese. forgot the name.

      Master Broth Recipe: https://twitter.com/thesquattingman/status/1737526599023526043 / https://recipeats.org/master-broth/

      onliestO jamezb46J 2 Replies Last reply Reply Quote 0
      • onliestO
        onliest @CO3
        last edited by

        @CO3 tyramine

        TahodamaT 1 Reply Last reply Reply Quote 0
        • TahodamaT
          Tahodama @onliest
          last edited by Tahodama

          @onliest
          Ah, looking it up now. Yeah that explains it. I'm also reading that pasteurized dairy (both present in my smoothie and cheesecake) are low in tyramine, which explains why I didn't feel any symptoms of high BP. I was also taking ~1g of aspirin before bed which may've helped.
          Still intrigued I didn't notice any drastic changes in my hormone profile. Or maybe I'm just horribly unobservant.

          1 Reply Last reply Reply Quote 0
          • ErikaE
            Erika
            last edited by

            Thinking of starting supplementing Methylene Blue as I'm having some low blood oxygen issues. Anybody have some useful info on what would be a good daily dose? Thanks:)

            onliestO MartiñoM 2 Replies Last reply Reply Quote 0
            • onliestO
              onliest @Erika
              last edited by

              @Erika I'd start with 1-2mg and avoid other MAO inhibitors to be safe.

              1 Reply Last reply Reply Quote 0
              • MartiñoM
                Martiño @Lothric
                last edited by

                @Lothric wow that is a really high dose. I started taking it last week (took one bottle from the lab at Uni) and just 3 drops are enough for me to feel the nootropic effects. The other day I tried taking like 9 drops through the day and i started peeing blue-ish green, so I wouldn't recommend taking that much as you can feel the effect with 1-2 drops in like half liter of water.

                Anyways I'm a rookie with Methylene blue it's just my opinion analysing the start of my usage.

                1 Reply Last reply Reply Quote 0
                • MartiñoM
                  Martiño @Erika
                  last edited by

                  @Erika I started a week ago with it, I couldn't find specific recommendations for a nootropic use. I just pour 3 drops in like half a liter of water and drink it with calm without rush. I feel the effects on my cognitive skills so for sure it's having effect on cardiovascular system and cellular levels too. That's my advice as someone that just started. Once i tried to put 3 drops directly to the tongue but the flavour is not so pleasant and you feel the intensity of it too much.

                  ErikaE 1 Reply Last reply Reply Quote 0
                  • ErikaE
                    Erika @Martiño
                    last edited by

                    @Martiño Interesting, I didn't know the nootropic effect was a thing. Definitely excited if it will have some effect of my mood. Thank you for sharing your experience with it.

                    1 Reply Last reply Reply Quote 0
                    • H
                      happyhanneke
                      last edited by

                      I have the mb from Idealabs called oxidal. I only take one drop every other day.
                      I hear you shouldnt take it with coffee. Yet there's caffeine in the bottle.
                      How does that work? I have put it in my coffee so I'm wondering if I shouldnt

                      jamezb46J 1 Reply Last reply Reply Quote 0
                      • jamezb46J
                        jamezb46 @CO3
                        last edited by

                        @CO3 Do you have any actual evidence that 7mg (likely 0.1 mg/kg) is "high dose"? It's used at 15-60 mg per diem for all sorts of mental health disorders and was used at doses far beyond that in world war I for months.

                        In time there is life but no knowledge; outside time there is knowledge but no life

                        1 Reply Last reply Reply Quote 0
                        • jamezb46J
                          jamezb46 @CO3
                          last edited by

                          @CO3 Lactoferrin probably

                          In time there is life but no knowledge; outside time there is knowledge but no life

                          1 Reply Last reply Reply Quote 0
                          • jamezb46J
                            jamezb46 @happyhanneke
                            last edited by

                            @happyhanneke It potentiates the effect of the caffeine meaning any caffeine co-adminstered with the MB makes the effect of the caffeine as if you had taken approx a 10x dose of caffeine. So, if you take MB with 10 mg caffeine, you get an effect from the caffeine as if you had taken 100mg caffeine.

                            In time there is life but no knowledge; outside time there is knowledge but no life

                            alfredoolivasA 1 Reply Last reply Reply Quote 0
                            • alfredoolivasA
                              alfredoolivas @jamezb46
                              last edited by

                              @jamezb46 That is not true, I am pretty sure that idea was conjecture, spread by Haidut back in the day. I have had 600mg of caffeine and 10-15mg caffeine on the same day, and no, it felt like 600mg of caffeine not 6000mg.

                              jamezb46J 1 Reply Last reply Reply Quote 0
                              • jamezb46J
                                jamezb46 @alfredoolivas
                                last edited by

                                @alfredoolivas yes that’s where I got the idea. But maybe it’s true at low doses and not high. In other words maybe the potentiation is 10x at very low doses of caffeine like 1 mg but approaches 1x as the amount increases toward some value like maybe 10mg caffeine.

                                In time there is life but no knowledge; outside time there is knowledge but no life

                                alfredoolivasA 1 Reply Last reply Reply Quote 0
                                • ?
                                  A Former User @Tahodama
                                  last edited by A Former User

                                  afaicr (as far as I can recall) 5mg MB 3x a day is the safu dose for self-treating various issues. it's interesting because 5mg 3x a day is the safe DHEA dose too

                                  peat is more conservative and iirc recommended like 70mcg as a safe dose. The quote from him says to take it in similar doses as thyroid hormone.

                                  . for general wellness (a supplement you take for health benefits that you don't really obliquely notice acute effects from), something like 0.5mg a day is probably totally fine. don't take it with iron rich foods or vitamin E

                                  I took like 100-150mg a day for like 2 weeks during wuflu. I can't say if it really helped. I have a suspicion it caused or contributed to what I think is iron lipofuscin on my finger that gradually disappeared since. I was also on a whack of cyproheptadine so that would have mitigated any potential excess serotonin effects.

                                  the first time I ever took MB at like a 1mg dose I got this strange and not totally unpleasant sensation that my vision was widening and getting better.

                                  jamezb46J 1 Reply Last reply Reply Quote 0
                                  • jamezb46J
                                    jamezb46 @A Former User
                                    last edited by

                                    @sushi_is_cringe

                                    Yes, the 5 mg, 3x per day sounds right. 15 mg/day is where some of the clinical trials start with mental illness sufferers like depression.

                                    In time there is life but no knowledge; outside time there is knowledge but no life

                                    1 Reply Last reply Reply Quote 0
                                    • alfredoolivasA
                                      alfredoolivas @jamezb46
                                      last edited by

                                      @jamezb46 Haidut says a lot of stuff man... here is a clip of him saying a few mgs of exemestane, allows him to drink 2 litres of Vodka in a single night. In most countries that is equivalent to 67 shots of vodka...
                                      Youtube Video – [1:17:50..]

                                      I wouldn't take his words as gospel.

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