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    Reversal of hair loss in Mice with “sugar gel”

    Literature Review
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    • R
      Rah1woot @CrumblingCookie
      last edited by Rah1woot

      @CrumblingCookie What method of application did you use for the iodine on the scalp?

      I've had such great success with using povidone iodine (whose action is a delayed release of iodine) for other fungal infections that I'm still pretty keen to try it on the scalp, to be honest.

      I believe what you say about the harm to the follicles, but I would also think it's not a huge deal if used for intermittent treatment, and then washed off.

      But this is getting somewhat off the thread topic of sugar gel and hairloss.

      I will make a separate thread @CrumblingCookie and tag you.

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      • H
        Hearthfire @Rah1woot
        last edited by Hearthfire

        @Rah1woot @CrumblingCookie

        I am positive even a small amount of iodine would help if you have a fungal infection in the scalp. How much did you use, CrumblingCookie? Did you notice it drying out your hair or something? If it was a large amount you tried, maybe just mixing in a couple drops with whatever shampoo you use, and increasing until you see negative effects would be the play. Then reduce it a bit.

        My brother has been dealing with a ringworm infection on his hand, I'll be recommending he try the iodine. Thanks for that info. Will also try the borax.

        @Rah1woot said in Reversal of hair loss in Mice with “sugar gel”:

        But this is getting somewhat off the thread topic of sugar gel and hairloss.
        I will make a separate thread @CrumblingCookie and tag you.

        I mean, this thread has evolved into a general discussion of hair loss and treatments already. But maybe it would be good to have a hair loss general so to speak, for easier discoverability for future users.

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        • C
          CrumblingCookie @CrumblingCookie
          last edited by CrumblingCookie

          I've been pondering on whether to also include D-Biotin in the topical to go along with dexpanthenol.
          Wrt to topical apigenin, topical biotin, and topical oleanolic acid (olive tree leaves extract @Mauritio) there's a commercial product with these ingredients called Procapil supposed to induce hair strengthening and anti-hair loss treatment by improving poor scalp micro-circulation, follicle ageing and follicle atrophy. Interestingly, the same company also markets "Apiscalp" to fight dandruff, itching, dryness and hypersoborrhea. It's active ingredient is of course: Apigenin. And caprylic acid (antifungal). That's it. Elegant.
          In the Procapil they actually include "biotinoyl tripeptide-1" for biotin, which is

          "a vitaminized derivative of Tripeptide-1, a matrikine that stimulates hair follicle metabolism and anchoring. It reduces hair loss by inhibiting DHT, improving blood irrigation, and activating hair growth genes [...] stimulating the production of anchoring molecules"*
          "Tripeptide-1 (GHK peptide) is a fragment of collagen type I that stimulates collagen and hyaluronic acid synthesis, protects collagen fibers, and scavenges reactive carbonyl species. It helps prevent wrinkles, photo-aging, and DNA damage from pollution and sun exposure."*

          Tripeptide-1 is actually synonymous with GHK. It's also synonymous with Prezatide. Peptide-interested people will have read about copper-GHK. I always wondered why I would want such extra copper. It seems the GHK-part itself is effective and can combine with other substances like biotin.

          Overall, both topical biotin and topical tripeptide-1 appear interesting.
          In an Italian study on short anagen syndrom in children (link), which is a special genetic condition, administration of oral biotin alone drastically improved the anagen:telogen ratio.
          But I'm wary of biotin because it impedes the crucial B5-uptake so I'm liking the idea of topical administration (perhaps 0.1% 0.05%?) in combination with dexpanthenol of which the uptake shouldn't be inhibited by biotin.

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          • MauritioM
            Mauritio
            last edited by

            Just a quick update: i stoped applying because it was making my hair very dry. I suspect it was the alcohol.

            Dare to think.

            My X:
            x.com/Metabolicmonstr

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              heyman @Mauritio
              last edited by

              @Mauritio I like how solban (I make my own) makes my hair feel, very nice

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              • L
                LetTheRedeemed @Mauritio
                last edited by

                @Mauritio interesting. Thoughts on diluting with more water?

                MauritioM 1 Reply Last reply Reply Quote 0
                • MauritioM
                  Mauritio @LetTheRedeemed
                  last edited by

                  @LetTheRedeemed Well that would take me waiting until all the damaged hair has grown out which would take about 1 year. After which I'm not going to damage my hair for another year by trying out a less strong version.

                  Dare to think.

                  My X:
                  x.com/Metabolicmonstr

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                  • W
                    wester130 @Mauritio
                    last edited by

                    has anyone tried tropical pycnogenol ?

                    it can work like minoxidil in its effect for increasing bloodflow and opening up blood vessels

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                    • L
                      LetTheRedeemed @Mauritio
                      last edited by

                      @Mauritio interesting… i personally haven't seen damage.

                      MauritioM 1 Reply Last reply Reply Quote 0
                      • MauritioM
                        Mauritio @LetTheRedeemed
                        last edited by

                        @LetTheRedeemed good for you . Then keep going ! Don't want to discourage anyone. I think I just have sensitive hair.

                        Dare to think.

                        My X:
                        x.com/Metabolicmonstr

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                        • L
                          LetTheRedeemed @Mauritio
                          last edited by

                          @Mauritio if you dont mind my asking, what does the damage look like?

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