Posts made by Dedeluded

@alfredoolivas Some effects are systemic. Maybe not equivalent but more convenient. You can have a 850 light in the background and not even notice.

Really nice study. thx

John Wick is missing for some reason. I fix

@flac said in paranoia:

meditating on the breath for 10 or 20 minutes

Things like this can help nearly everyone. I think this falls under the practicing mindfulness idea like focusing on what you eat very carefully.

I was hoping industry would develop a low pufa version like they did for the peanut. Now there's no reason to give these things a single thought which is good to know.

a pointless trash food

@sushi_is_cringe said in paranoia:

@herenow "No pill or lifestyle change will fix destructive thought pasterns."

depends

You're exactly right.

What I meant is keep trying different drugs and drink more milk.
Lift heavy
Creatine

Then:
Career (say doctor or lawyer)
Nice Car
Girlfriend
Beautiful wife
Happy healthy kids

And then you're fixed

Just to sprinkle a little Ray Peat magic on this thread

https://pmc.ncbi.nlm.nih.gov/articles/PMC9053330/

Long-term Aspirin Use and Epigenetic Mitotic Clocks for Cancer Risk Prediction: Findings in Healthy Colon Mucosa and Recommendations for Future Epigenetic Aging Studies

Conclusions:

Our observed findings support previously reported longitudinal associations of aspirin use with deceleration of other epigenetic age measures in the proximal colon. Our mitotic clock results suggest that cell proliferation could play a role in some aspirin relationships with epigenetic aging. Furthermore, the findings provide added impetus for establishing gold standards for epigenetic aging and consensus guidelines for more comprehensive reporting in future epigenetic aging cancer studies.

and another:

https://pmc.ncbi.nlm.nih.gov/articles/PMC7450956/
Aspirin mediates histone methylation that inhibits inflammation-related stemness gene expression to diminish cancer stemness via COX-independent manner

one more:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9681612/
Aspirin Mediates Its Antitumoral Effect Through Inhibiting PTTG1 in Pituitary Adenoma

Results
Aspirin induced global DNA demethylation and consequential transcriptome changes.

@Corngold said in The Official Skim Milk Discussion Thread:

I don't care. Not eating vegetable / insect cheese or soy milk.

I try to block out I'm eating a cow's utter secretion or chicken breast/boob meat. It's crazy how some things end up normal and other things end up strange.

Insects are probably good food but I can't get myself to eat them. I don't think they'd make good cheese.

NYC Law Student's Cheese Addiction Leads To $ 10K In Rehab
https://www.rttnews.com/3448972/nyc-law-student-s-cheese-addiction-leads-to-10k-in-rehab.aspx

@GlucoseGal She's probably an outlier tbh. Vegans push the narrative but people are weirdly committed to cheese.

Just to mention the obvious that nature would want milk to be addictive so the baby grows fast. That doesn't mean it's harmful but the poster asked why milk doesn't seem to be satisfying.

@Corngold said in The Official Skim Milk Discussion Thread:

@herenow lol of course they want to demonize dairy and cheese.

Maybe but that is exactly what a crack addict would say. It's always a conspiracy

LA TIMES

"Cheese really is crack. Study reveals cheese is as addictive as drugs"

...During digestion, casein releases opiates called casomorphins.

For anyone who's sees this:

No pill or lifestyle change will fix destructive thought pasterns. I've seen this myth destroy many lives.

People with the most to gain will avoid therapy the hardest.

@CrumblingCookie said in All things Histone Deacetylase (HDAC) and DNA Methyl Transferase (DNMT) inhibitory - reversing epigenetics from metabolic insults:

Or do you mean that the non-Rx substances could show similar toxicities like Rx over the course of time?

Like I take some methylene blue+caffeine=methamphetamine and then for reasons I can't understand I'm robbing a liquor store

It's a very interesting area

@of Nobody here can give you accurate answers. Your body is managing billions of variables and there's no way to know if your going in the right or wrong direction but lifestyle changes are not likely to make a dent.

If you panic and throw a bunch of new drugs at the problem you'll end up with new issues. Most likely the problem will just go away but you have to stop taking something or lower the dose.

@of You've increased the number of variables in your life massively by using so many chemicals.

There could be an interaction between the drugs where they wouldn't cause this on their own.

Drug withdrawal can also cause dystonia.

I doubt it's permanent.

@of said in paranoia:

@herenow I'm not paranoid anymore the main issue is my fucking dystonia.

"Acute dystonia induced by drug treatment can be caused by antipsychotic, antiemetic, and antidepressant drugs"