Posts made by izkrov

@rosenstein I think when the liver is overburdened you're not converting T4 to T3 as much, so the liver spends time (inefficiently) detoxifying whatever comes through. Supplementing active T3 while the liver is preoccupied speeds up the process. Just generally the higher the metabolic rate (T3), the more efficient the liver.

Could be the liver being overburdened from detoxifying lactic acid from working out hard and so some toxins end up being being excreted on the skin (hence the acne). Taking thyroid relieves the liver and that's why the acne goes away. I imagine the same logic applies to a big meal or 2Ls of milk with the liver being overburdened.

Haidut not too long ago posted about how he lost a lot of weight by eating no fat, just protein and carbs (yet increased total calories eaten), and supplemented vitamin K3.

There's also a lot of studies of people taking thyroid and losing a significant amount of weight quickly. You don't really need to go that far, as long as you increase metabolism you will lose weight.

@cs3000 said in Dry eye disorder is often caused by hormone deficiency (restored by increasing testosterone):

because testosterone levels also drop in menopause, and the low estrogen is a sign of low testosterone

You have a preconceived notion and you're using some random combination of words to prove it. Low estrogen is a sign of low testosterone? I better go drink some soylent for some larger gains then. Genuinely retarded.

even though low estrogen is connected to dry eye disorder

Women are high in estrogen in menopause, this is completely wrong.
A quick example to disprove this would be that St. John's Wort is highly unsaturated (and therefore estrogenic) and it causes retina damage. Many people report some kind of sensitivity to light and dry eyes. Progesterone opposes estrogen and fixes that issue. Source: me after I took progest-e. Ray even wrote about this:

The popular supplements melatonin, tryptophan, fish oils, St. John's wort, and the various omega -3 oils, all increase the risk of retinal light damage and macular degeneration. Serotonin uptake inhibiting antidepressants are suspected to be able to cause it.

https://raypeat.com/articles/articles/aging-eyes.shtml

This really isn't so simple as just low T. Why don't you go on raypeat.com and actually read some of the articles first

Do not apply progesterone to your nipples.

My friend feels lightheaded after taking nicotine with coffee, I'd be wary with it. Make sure you're also drinking coffee with a meal as well, preferably meat, from what I remember coffee on an empty stomach increases nitric oxide.

I think one of the structural changes of hair loss involve a more circular forehead, with a pointier top of the skull -- the more egg shaped head. Assuming this is for men, when you take a certain amount it makes you temporarily baby faced with a smaller skull size and softer scalp. If you think of someone's bald shiny head, the scalp area is really rigid. Progesterone makes the tissue less dense and probably less fibrotic. Though I also think if you take too much it'll make your hair not as thick as it should be, because at that point you'd be opposing testosterone.

It's certainly a better finasteride.

I don't see any additives in the Kirkland Organic Coconut Water. Pretty unscathed from zog.

I don't suppose you have some l-theanine and caffeine lingering around, that would help
Honestly if I were you I'd just have a beer. You really only need a few sips.

His New Avatar Is Holding A Gun In It's Mouth!

get some sleep man

@Hugh I have tried topical application as well on the scalp and wrists without much effect

Tried 4-5 drops orally first time, felt an immediate nootropic effect. Kind of like you're being reminded to breathe manually, but the focus being the eyes, it's that kind of thing awareness.
Every time after I felt absolutely nothing, no matter the dose used.

Someone on RPF seemingly resolved it by lowering prolactin, in this case by taking bromocriptine

@angel I understand that it's the standard protocol, but I still don't think it's safe. Testosterone aromatizes to estrogen, the negative effects you're feeling are from high estrogen and anyone that says it's from low estrogen is deeply wrong. I got the 4mg number from here:
https://youtu.be/E21sYPiYHtM?si=ZRvzpTfYgS97zhYz&t=265

@HeightOptimized Until you have a study that shows calcium intake along with caffeine, there is no evidence to show that "it just pauses growth plates".

That seems like unphysiological amounts of test/dht. I don't think ray recommended more than 4mg of test, and that's after thyroid/dhea/pregnenolone were okay.
During stress, testosterone aromatizes to estrogen, and those symptoms are highly conducive of that.
An aromatase inhibitor like aspirin would be good, and progesterone to oppose the estrogen.

https://twitter.com/TakeThiamine/status/1772230860441313517

these look tasty

@HeightOptimized I don't understand.

@HeightOptimized said in Caffeine is BAD for GROWING TALLER:

https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-11-56#:~:text=Current evidence however relate caffeine,reducing intestinal calcium absorption efficiency.

This article cites the exact same author from the study I linked -- R P Heaney. He himself said there's really not that much of an effect on calcium absorption, saying "Current evidence relates caffeine to reducing calcium absorption efficiency" is just outright wrong, or misses the fact that very small amounts of calcium intake can offset the negatives.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475355/

Estradiol levels in the controls were relatively consistent, without age variation (Fig.​(Fig.6b).6b). However, caffeine-fed rats exhibited a significantly higher E2 level after 2 weeks of caffeine exposure compared with the controls (P < 0.01 vs. CT). After 4 weeks of caffeine exposure, E2 levels in the caffeine-fed groups were profoundly decreased compared with those measured at 2 weeks, and even lower than for the controls. In addition, total T4 levels of serum samples obtained after 4 weeks of caffeine exposure only were measured, due to a shortage of 2-week serum samples (Fig.​(Fig.6c).6c). Caffeine-fed groups showed significantly reduced levels of T4 compared with the controls (P < 0.05 vs. CT), no difference was observed between the caffeine-fed groups.

This study I think shows decently what's going on. High caffeine intake relative to calcium intake (they simply didn't give them calcium) is stressful in nature, hence the estrogen increase. Caffeine helps convert T4 to T3 in the liver, but without the increase in nutrients to meet the metabolic demands the only thing the cells can do is divide. Eventually though there's a stabilizing effect

Most of the links you posted are broken, and even from the captions don't seem relevant.

From this study:
Low calcium intake is clearly linked to skeletal fragility, and it is likely that a high caffeine intake is often a marker for a low calcium intake. The negative effect of caffeine on calcium absorption is small enough to be fully offset by as little as 1-2 tablespoons of milk

Other studies which I think you have linked (I can't know because you didn't copy paste correctly) seem to use intravenous caffeine rather than oral intake. I'm not sure it's safe to bypass the liver like that.