Sativa marijuana is peaty
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the marijuana types that gets a bad reputation are the shorter harvest bred indica crosses which produce a big body stone and sleepiness a lot of times. they are good for indoor growing and mature quickly with big yields and therefore have become the common cash crops.
there are marijuana strains from the tropical regions that grow differently and the effect is mostly mental. some have very little come down or tired-ness if any, and are more akin to a cup of coffee than a narcotic effect. they are difficult to grow indoors (and nearly impossible outdoors outside of the tropics), because they get very tall and stretchy and take many months to mature their flowers and the yield is relatively small, and therefore they are not grown by cash croppers. and often they don't have the marketable bag appeal that the more common strains have.
I think these strains are good for exercising and playing sports and probably don't have the estrogenic effects as common marijuana strains do.
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I think marijuana is more progesteronic. It is not estrogenic.
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@Ecstatic_Hamster probably depends on the types, ratio, amounts of plant chemicals in it
someone on a cannabis forum actually said that this medical industry focus on CBD actually harmed the diversity of marijuana out there because raising CBD is at expense of other things. I saw mentioned that when Thailand legalized marijuana their army distributed lots of CBD heavy genetics around.apparently there are things that aren't commonly tested for in marijuana that are interesting and potentially beneficial. I just read the above comments cursorily so please excuse me if im presenting an idea not correctly stated.
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Peatbot: Ray Peat mentioned that he has been looking for the real beneficial effects of THC and CBD, but he finds the effects to be very ambiguous. He noted that in some circumstances, they can be anti-inflammatory, but not always. He expressed that he hasn't been able to resolve the ambiguity to form a definite opinion on the matter.
And from peaty friendly Analyze & Optimize:
What they tell you weed does:
Nothing, it's harmlessWhat it really does:
☒ Decreases key neurotransmitters (dopamine, acetylcholine, GABA, glutamate)
☒ Reduces brain volume
☒ Alters brain structures (amygdala, nucleus accumbens)
☒ Reduces reward perception
☒ Reduces separation of logic & emotion
☒ Impairs memory
☒ Impairs mitochondrial function
☒ Lowers IQ
☒ Increases depression risk
☒ Increases anxiety risk
☒ Increases risk of suicidal ideation
☒ Drastically increases risk of schizophrenia
☒ Massively increases risk of psychosis
☒ Increases risk of several cancers (all head + neck, laryngeal, nasopharyngeal, oral, oropharyngeal, salivary gland, testicular)
https://x.com/Outdoctrination/status/1903043866640437563 -
@eduardo-crispino said in Sativa marijuana is peaty:
there are marijuana strains from the tropical regions that grow differently and the effect is mostly mental. some have very little come down or tired-ness if any, and are more akin to a cup of coffee than a narcotic effect.
If you are conscious of this collateral effect ...
Marijuana THC alters brain synapses
There are more than 70 varieties of Cannabis sativa, of which the primary psychoactive component is THC (Δ9-tetrahydrocannabinol), at more or less high level. Using marijuana induces synaptic changes, when repeating the practice (e.g. usual smoking during the weekend).
*) Effects of Marijuana Use on Brain Structure and Function
THC appears to block synaptic plasticity and neurogenesis, particularly in hippocampal regions, which can have an effect on brain volume (Mato et al., 2004). THC has also been shown to interfere with mesolimbic dopamine pathway functioning (Bossong et al., 2008; Kolb, Gorny, Limebeer, & Parker, 2006).
Int Rev Neurobiol. 2016 Jul 20;129:33–65. doi: 10.1016/bs.irn.2016.06.004
Varieties of marijuana (Cannabis sativa) contain over 70 identified cannabinoids, of which the primary psychoactive component is THC (Δ9-tetrahydrocannabinol). The potential effects of THC on brain functioning are equally broad. THC exerts its effects on CB1 receptors are distributed broadly throughout the brain with particular areas of concentration in prefrontal, cerebellar, temporal, and hippocampal regions (Burns et al., 2007; Glass, Faull, & Dragunow, 1997; cf. Fig. 1B).
CB1 receptors = cannabinoid receptors type 1.
*) Synaptic changes induced by cannabinoid drugs and cannabis use disorder
In some regular cannabis users, CWS occurs after the cessation of cannabis use.
CWS = cannabis withdrawal syndrome.
https://doi.org/10.1016/j.nbd.2022.105670 -
Indeed the classical varieties provide more desirable and balanced effects like mental clarity & lucidity, mainly thanks to lower THC levels and more varied cannabinoid & terpene profiles. Classically THC was at ~5–15%, with CBD, CBG + stimulating terpenes. Thesedays THC is at 20+% with low/zero CBD/CBG... thanks to commercialisation re introduction of shorter flowering genetics and focus on higher THC %.
@LucH
Looking at THC alone and making broad conclusions doesn't give an accurate picture of things. There's a complex entourage effect going on between numerous pharmacologically active substances eg cannabinoids (CBD, CBG, THCV) and terpenoids (which are common constituents of plant essential oils eg limonene, linalool, pinene, myrcene). Aromatherapy...CBD acts to balance THC.
CBG is an α2A agonist which reduces adrenaline and is pro-GABA.
Cannabis terpenes are valuable too... pro-metabolic (phytol), pro-dopamine, anti-cortisol, anti-serotonin (limonene), pro-GABA (linalool), pro-BDNF (beta-caryophyllene).A seed company called ACE seeds carries many classic "sativa" tropical cannabis genetics, here's the description for one:
Clean, energetic, all in the head 'Feel good!' sativa effect of moderate strength and duration, without ceiling, tiredness in the body or hangover.
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@wrl said in Sativa marijuana is peaty:
the classical varieties
I'm partial. A small amount, a couple of times a week, in a dry herb vaporiser. It's getting hold of that kind and not letting it become a daily habit that's tricky.
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@ThinPicking Aye. Hemp varieties can be a good combo for a more balanced THC experience, CBG and CBD flowers exist. And if adventurous you can customise/enhance your journey using essential oils applied with a toothpick (either direct onto flower or on the rizzla). Or perhaps you already practice more conventional aromatherapy!
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@wrl said in Sativa marijuana is peaty:
CBG is an α2A agonist which reduces adrenaline and is pro-GABA.
but CBG is also a 5-HT1A antagonist at 52nM: Not "peaty" at all.
Whereas CBD is a partial 5-HT1A agonist and therefore less objectionable.
THC again is serotonergic and exhibits those detrimental effects on gonadal functions, androgenic hormones and fertility etc. as already mentioned before by the others. So pushing THC and prohibiting or muddling with clean tobacco smoking fits well into the trend of a widely known general agenda.Those terpenes likes limonene etc. may be much more exciting. But yes then any kind of aromatherapy and vaporisation of other medicinal herbs become just as interesting.
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@CrumblingCookie said in Sativa marijuana is peaty:
So pushing THC and prohibiting or muddling tobacco smoking fits well into the trend of a widely known general agenda.
I did find the whole liberalisation of dank hydroponic sludge in the last decade a bit suspicious. And quietly hoped the attitude wouldn't find it's way to England. I don't mind that it's "illegal" and I have to do gymnastics to get it, personally.
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@CrumblingCookie said in Sativa marijuana is peaty:
but CBG is also a 5-HT1A antagonist at 52nM: Not "peaty" at all.
THC again is serotonergic and exhibits those detrimental effects on gonadal functions, androgenic hormones and fertility etc. as already mentioned before by the others.Sure, but in the context of classical cannabis genetics CBG % was very low, and THC % also. Terpenes could feasibly mitigate any serotonergic and metabolic effects. A coffee and tobacco would do the rest!
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@CrumblingCookie said in Sativa marijuana is peaty:
So pushing THC and prohibiting or muddling with clean tobacco smoking fits well into the trend of a widely known general agenda.
Yup, similar to how traditional gruit was replaced with hops beer. Gruit was apparently consumed by people of all ages and regions had different ingredients.
