Posts made by Kvirion

@CO3 Oops, good to know, thank you for the info!

@Cezar4911 said in Thyroidic sleep:

Have any of you here managed to reach this optimum state?

It's reachable but it requires a lot of systemic and systematic work...
Proper nutrition, movement, and environment; adequate levels of things like Ca, Mg, Zn, ADEK, B-vitamins, lowering cortisol and adrenaline first, etc... Continuously Perceive. Think. Act...

BTW "Because the actions of T3 can be inhibited by many factors, including polyunsaturated fatty acids, reverse T3, and excess thyroxine, the absolute level of T3 can’t be used by itself for diagnosis."
https://www.functionalps.com/blog/2012/03/25/ray-peat-phd-on-thyroid-temperature-pulse-and-tsh/

@Uncover said in Open-label trials - how is this allowed?:

The most fun part about it is there is awlays something to learn even when I think im almost done I find a new part of the puzzle

Yeah, I've similar feelings here - it's probably nested like a Russian doll... One can think that he is out of the cage, but then turns out one is still inside a bigger cage...

& @MarkusAllenUSA
Regarding Open-label trials - besides what has been already written - and I agree with, another reason is that they are simply cheaper... And knowing that double-blind study can be sophistically manipulated too, then what's the difference?

https://medium.com/@vohchenwei/the-risks-and-realities-of-data-manipulation-in-clinical-research-a-critical-analysis-for-medical-aea5d9207887

Especially knowing that today most researchers are not aware of the limitations of their own work... Ray wrote about this:
https://raypeat.com/articles/articles/authoritarians.shtml
https://raypeat.com/articles/articles/adaptive-substance.shtml
https://raypeat.com/articles/articles/intuitive-knowledge.shtml

@Lloyd Try his store address info@idealabsdc.com
Or via Twitter/X: https://twitter.com/haidut

@yerrag Sorry to hear about your troubles, I wish you well and a quick recovery!

Never trust GenAI about nuanced, subtle, or fuzzy topics. GenAI doesn't think or reason; it just makes statistical inferences between words.

In technical terms, fennel seeds can increase serotonin, but practically not - the amounts are insignificant!
(It is about weak MAO inhibitions)
https://pmc.ncbi.nlm.nih.gov/articles/PMC3521852/

The most probable mechanism is significantly increasing GABA, which should help with deep sleep.
https://ppj.phypha.ir/article-1-664-en.html

BTW be careful with fennel it can also increase estrogen...

Substances known to potentially lower serotonin: S. Boulardii, lavender, Shilajit, beta-alanine, Ca, Mg, glycine, lysine, Tyrosine/DLPA + BCAA, Aspirin, vitamin B9, B1, quinones, caffeine, creatine, Schisandra, inosine, theanine, propolis, Siberian ginseng, PRL-8-53, LSD, and Manganese; avoiding PUFAs…

@LetTheRedeemed said in Bryan Johnson cooling himself for longevity? Waking temp of 93.4. Seems like a bad idea:

Low temps makes my bones harder you say?

LOL! Good one! You know what I meant

Sometimes grammar isn't my friend...

@LetTheRedeemed said in Bryan Johnson cooling himself for longevity? Waking temp of 93.4. Seems like a bad idea:

bone repair

By my understanding low temp makes it much harder:
"A high level of respiratory energy production that characterizes young life is needed for tissue renewal."
https://raypeat.com/articles/articles/osteoporosis-aging.shtml
+
"Thyroid and progesterone, unlike estrogen, stimulate bone-building, and are associated with a decreased risk of cancer. It seems sensible to use thyroid and progesterone for their general anti-degenerative effects, protecting the bones, joints, brain, immune system, heart, blood vessels, breasts, etc."
https://raypeat.com/articles/articles/osteoporosis.shtml

@LetTheRedeemed said in The immortal, eternal Bryan Johnson broke his frail, childlike ankle while dancing at age 47:

temp's impact on bone health

Easy

Peatbot: The body's temperature can impact bone health by influencing metabolic rate and hormonal balance. A balanced metabolism, indicated by a stable body temperature, supports efficient oxidative metabolism, which is crucial for maintaining bone health. High calcium intake, associated with increased metabolic rate, can help suppress parathyroid hormone, which otherwise can harm the bone by blocking the use of oxygen in tissues and leading to the production of lactic acid in the bone. This lactic acid can dissolve bone and contribute to osteoporosis. Therefore, maintaining a stable and optimal body temperature can support bone health by promoting efficient metabolism and hormonal balance. Additionally, exposure to sunlight, which helps in the production of vitamin D, is important for bone density, and maintaining a good metabolic rate can support this process.

Just saying... https://bioenergetic.forum/topic/3501/the-immortal-eternal-bryan-johnson-broke-his-frail-childlike-ankle-while-dancing-at-age-47

@Insomniac Thanks, interesting, and another proof for the superiority of holistic Ray's ideas above mechanistic biohacking

By the way.
Ray and Haidut had mentioned in many articles and interviews that PUFAs only temporarily suppress inflammation but do not heal it.
Therefore all such information as research above should be taken in a proper (complex/holistic) context.

Peatbot: According to the context provided, polyunsaturated fatty acids (PUFA) can have an anti-inflammatory effect, but this effect is primarily due to their oxidized form, which suppresses the immune system. This suppression can interrupt an existing inflammatory process, but it does not necessarily lead to healing. In fact, prolonged use of PUFA for its anti-inflammatory effects can result in immunodepression, which is a longer-range effect. Therefore, while PUFA may suppress inflammation, they do not necessarily promote healing and can have toxic effects in the long run.

@Samyo Unfortunately, it looks like you are in an infinite loop of fighting with symptoms...

Firstly, focus on metabolism and then adjuvant therapies
(as @himblondemaxxing and @yerrag already mentioned)

Health issues are not meant to be addressed directly. You heal by simply out-nourishing the issue. Until it feels like all aspects of your life are improving in unison, you are not adequately nourished. It should feel like nothing can break your stride. The bioenergetic symphony. ~@natelawrence_

My sincere congratulations to all USA citizens!
I'm happy for you and hope that the EU will follow...

Try Noopept if you are brave enough...

Noopept boosts Alpha and Beta brain wave activity. You become calmer and more creative. It’s easier to go into a flow state. And you are prone to making innovative and resourceful decisions.

@hcwilliams said in How would you come off of TRT without PCT?:

Sounds good.

Been 5 days since last injection. E2 and serotonin notably still high.

I would also add some Aspirin (plus K2-mk4) to the mix, which should help lower serotonin and E2 levels. And also "refresh the pipes"...

More about it: https://testonation.com/2023/05/22/aspirin-on-testosterone-dopamine-and-sexual-function/

"Enhanced cysteine transport and its metabolism enable cancer cells to adapt to a challenging tumor microenvironment and acquire chemoresistance. This section discusses the role of cellular signaling molecules and proteins in regulating cysteine metabolism in cancer development and drug resistance."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893486/

"NAC may also accelerate the progression of some cancer growth."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563555/

Haidut also speaks against NAC - can't find a specific podcast now; it was one done with Strong Sistas.

@Jennifer said in Why it's hard to overcome a bad childhood. Dr. Lipton explains that 95% of our operational programming is completed by age 7:

We can lead a horse to water with the intention of having it drink, but what if it doesn’t believe it can drink because all the other horses don’t believe they can drink so they don’t? Thank God for all the exceptions breaking the rule.

Yes, is so well said. I noticed that some of my friends are willing to improve and some will do everything to avoid facing their demons... and stay being a (traumatized) normie - with their mantra - next time I will do the same but better...

@Insomniac said in Why it's hard to overcome a bad childhood. Dr. Lipton explains that 95% of our operational programming is completed by age 7:

In my case I had attempted to block out my past and focus on things like chemicals, hormones, environmental toxins, food, light and exercise but ironically ignoring my past was not helpful to moving forward because it should be involved in your search for solutions.

In my experience "getting sceletons out of the closet" i.e. understanding my traumas and accepting them was a beneficial moment/process in my life. It got me solid ground to try to get past them to some extent and try to build on them... Like being more in control of myself (with the help of psychology and biology) and understanding better how humans perceive reality. It helped me to stop being a normie/midwit i.e get out of the Matrix
Moreover, for example, I used my tendencies for anxiety and pessimistic outlook to become a specialist in risk management, etc.

BTW Interesting longer podcasts with Dr Lipton

• https://www.youtube.com/watch?v=BR5MfCCyUoQ
• https://www.qualialife.com/people/bruce-lipton-phd?