Topics created by haidut

No wonder that we seem to be on a never ending decline when it comes to young people's mental health. What chance do kids have when before they're even born they are exposed to even more and more chemicals that mean they are more likely to be dumb and sick.

One upside I guess is if you're aware of this and you and your partner don't eat PUFA you're going to have a child with an automatic leg up compared to everyone else.

Where do ppl buy it from?

@haidut Fantastic research. And great presentation of the pathogenicity of estrogen, once again.

@Mauritio said in Niacinamide as effective as minoxidil at treating “androgenic” hair loss:

@Mossy I stopped using them topcically, because it was such a mess to apply. But looking backon it that was because of the apple juice i diluted it in.
So maybe I'll give the polyphenols another run mixed with niacinamide and glucose and water.

I hear you. If there's one thing I've learned over the years with these topicals, at least for me, they're impossible to use on a regular basis, apart from during sleep, due to the mess.

The glucose would seem to be a mess, no matter the form. On those lines, I've been thinking of using the common D-Ribose supplement, as opposed to the much more expensive variant of it used in the studies.

I have over the last year gotten a grip on superior health. I have religiously trained grip strength every Sunday a year straight and returning to moonkey has improved every major aspect of my life.

Bitch, superior grip strength was an absolute game-changer. It’s one of those things you don’t realize you’re neglecting until you start pressing your fist around a woman's breast, and then suddenly, everything in life feels more erect. Grip strength is the key to superiority. It’s involved in every physical thing you do, and when you improve it, it’s like unlocking a cheat code for life. I feel like I’ve got lobster claws for hands. Pull-ups? Gavity is just a debunked theory now. I’m basically a human forklift. It’s insane how much my sex appeal has improved by having superior fists. Women completement my fists all the time. Being fisted by me is a bragging right at the town hall.

My hands are no longer hands, they’re weapons of mass destruction. It’s like I’m investing in my own survival, one hand squeeze at a time. There’s something primal and satisfying about having a superior grip. It makes you powerful. I now walk into rooms knowing I could rip the door off its hinges if I wanted to. Handshakes aren’t just greetings anymore, they’re power moves. Grown adults wince when I grip their hand, and I’m not even trying. I am the alpha moonkey in all social situations, because my grip radiates dominance. People feel it. They know. They know.

If you’re not working on your grip, you’re just mastrubating your life away. I am now a Swiss Army knife of human capability, and it’s all thanks to my relentless grip training. My forearms look like they were sculpted by Michelangelo himself. Veins popping, muscles rippling. I catch people staring at my forearms in public, and I don’t even blame them. They’re mesmerizing.
But here’s the craziest part: grip strength has made me spiritually awakened. Every time I squeeze, I feel connected to my ancestors. Those ancient humans who had to climb trees, carry Pyramids, and wrestle saber-toothed tigers just to stay handsome. I’m tapping into primal sexual energy, channeling the raw (doggystyle), unbridled power of evolutionary design itself. I’m not just training my grip; I’m honoring the legacy of human moonkeys.

So yeah bitches, grip strength is a spiritual revolution. It’s the key to unlocking your true potential and ascending to a higher plane of existence. If you’re not training your grip, you’re not just mastrubating, you’re sleeping on the greatest upgrade of your life.

@haidut Great post, I wonder if clonidine could potentially be useful here.

@haidut one such Vitamin D derived peptide is known as LL-37, and there are anecdotal reports of it curing persistent foot fungus, (the kind “nothing” seems to work on) and lifelong “gluten intolerance.”

I know peptides get thrown into the trash bin of “bro science,” (and understandably not without reason) but I wish there was more data on them. While many of them work in ways contrary to a bioenergetic approach, I believe others synergize, and the MOAs are not clearly understood.

@haidut So this isn’t something someone can run a test for?

It’s crazy how close to useless blood tests are the more we learn of this stuff

Very interesting, I’ve had issues with runaway inflammation for years, but it’s only been in the last few as I incorporated Peat’s ideas that I’ve been able to sense it. Recently I’ve had tons of success with aspirin and b vitamins, but on occasion, (for reasons I’m still not sure on) I will get a big inflammatory response the entire length of my alimentary canal. I can literally see the inflammation of my gums when this happens.

Recently on a whim I tried some Panquinone, and the inflammation abated immediately. I checked the old thread on Panquinone for information about it being an anti-inflammatory, but there was no such mention. Sure enough, today I come across this information, and I have my answer!

Many thanks for your work Haidut!

Thank you @oldchem That's the book - looking to see if there is a pdf somewhere.

@Buckian Ive had similar experiences. I now only use red light therapy before my last meal of the day and never after

Haidut what are your thoughts on PPAR gamma antagonists for diabetes and obesity? PPAR gamma knockout mice have no adipose tissue. Niacinamide seems to downregulate PPAR gamma while niacin seems to upregulate it.

This study (a bit biased on SFA) claims palmitate activates it through NNMT which depletes NAD plus and niacinamide can counter that. And since SAM is what is needed for NNMT would increasing homocysteine for a while through depleting methyl donors w niacinamide etc be a good trade off ?

https://pubmed.ncbi.nlm.nih.gov/37212549/

Niacin also increases PPAR gamma , Im wondering how the mechanism differs for niacinamide (Is it abrogating PPAR gamma transactivation only when palmitate induced or is NAD plus the deciding factor)

https://pubmed.ncbi.nlm.nih.gov/16386710/

@Kvothe yeah they are trying to kill us .... bastards lollllll