@OliverCloasov @AinmBeo @Hearthfire
I'm open to a group buy if anyone of us can find a supplier to private individuals.
or, what if we all beseeched Georgi to make an experimental cosmetic in a one off batch and we be his guinea pigs?
Dandruff or scalp irritation? Try BLOO.
@OliverCloasov @AinmBeo @Hearthfire
I'm open to a group buy if anyone of us can find a supplier to private individuals.
or, what if we all beseeched Georgi to make an experimental cosmetic in a one off batch and we be his guinea pigs?
@Hearthfire yeah d-ribose is different. I know, I forget what context he said that about, too - like topical or just higher consumption.
@lulueatsmeat try lowering the cascara until you can take it - even if that's like an 1/8th of a teaspoon. I started out there or lower. even if you can only do a pinch, that'll do something to move the dial.
I think it's fine to experiment with t3 now if you have it - start at a really low dose, like 1 mcg.
sure, anything you have for gelatin. you can over do collagen pretty quickly, so be mindful of dosage. it's a free-peptide, not the whole proteins found in gelatin.
you can get glycine at healthfood stores if you have one near you.
“Ribose sugar has a hydroxyl (OH) group at position 2, whereas deoxyribose sugar has a hydrogen (H) atom at position 2.”
I’d love to hear thoughts on this… it’s pretty peaty unless there is something about the sugar used that’s not optimal that I don’t know about?
They used deoxyribose in a gel on the mice. It’s a natural sugar in animals and humans — it shouldn’t be dangerous…
EDIT: Danny did NOT say it increases NO. This is false
Yes, you have a gut and thyroid problem — and, a thyroid problem is a liver problem.
All the gut cleansers: carrot salad; well boiled blended white mushrooms; antibiotics like penicillin VK and the tetracycline classes, all help.
how long did you take cascara sagrada? Was it well aged dark brown? That one is very underrated, and it may take time to notice a positive effect. I emphasize it because of its multitude of benefits listed here:
https://www.saturee.com.au/blogs/blog-posts/cascara
Hypothyroidism absolutely slows transit time and contributes to bacterial overgrowth. poor liver metabolism absolutely contributes to digestion.
Aspirin, niacinamide, glycine, gelatin, cyproheptadine, will help heal the liver and improve mitochondrial respiration/general metabolism. Aspirin and glycine, and gelatin, as well as B vitamins thiamine and niacinamide, will help heal digestive tract. All these tools help move the dial toward thyroid supplementation being safer…
T3 also helps heal liver function and improve bowel movement. You can start really low on T3, like 1mcg every hour or 2. It’s more a risk to take hormonal supplements like progesterone or dhea.
It’s of course all case by case, but if you were making consistent effort with the above digestive improvements, you should be able to begin thyroid within weeks imo.
Utilizing an easy to digest sugar carb source, like juice, will be better in this state than more complex starches or whole fruits/vegetables. Lower protein may be helpful too. The glucose loading protocol is simply maintaining an easily digestible carb for a super compromised gut. Lower fructose foods should be fine, like maple syrup, pineapples, raspberries, cranberries. One starch exception would be sushi rice if you can tolerate it, it has almost no fermentable starch and converts into glucose quickly.
PS:
a) How much BCAA or gelatine do you reckon are necessary to compensate the AA-shift by every xx grams of dextrose (if there were no other dietary protein)?
b) Perhaps I'm being too dumb atm to see the mechanism behind these extracellular amino-acid shifts. Do they happen because the non-tryptophan amino acids are being "put to good use" by insuline and/or carbohydrates?
Good question. I don't really know. It sounds pretty low. Honestly, if one's liver function is so compromised they need to avoid fructose, then they should definitely be breaking up an already necessarily low protein intake, to multiple meals throughout the day... almost down to a few bites every few hours maybe.
let us know how it goes
@yerrag well, there’s a trend amongst conservative evangelicals to embrace traditional Catholicism and orthodox denominations, it’s a meme now I’m sure you’re aware of, called tradcath. I don’t think it’s a conspiracy akin to the old WASP anti-Catholicism sentiments.
I mean I'm relatively the same; grew up rural southern anti-catholic, and the subsequent culture wars showed me that catholics were always my friend -- then found orthodox to be way more conservative. These two denominations were basically the reactionaries in all the color revolutions, and protestants were often at least a few of the thought leaders in the general pro-revolutionary direction. I'll always be protestant, but I have friends who have gone orthodox after being raised protestant.
Really the only churches thriving right now in America are orthodox and Charismatic.
@Norwegian-Mugabe said in American presidential election 2024:
@Peatful I doubt it but it could happen. That is why it is so important that Nikki Haley and other neocons are not elected as VP. If Trump elects a neocon, I genuinely think he will die during the next few years.
JD Vance coming out not neocon
https://www.politico.com/news/magazine/2024/07/18/jd-vance-world-view-sources-00168984?utm_source=substack&utm_
That carbohydrates raise serotonin as a matter of certainty is dependent on the idea that carbohydrates always raise insulin, which I would say isn't always the case.
I agree, Ray has stated on multiple occasions that to reduce the insulin spike from protein, to consume a sugar item approximately 15 minutes before the meal (meal also well balanced with carbs).
So I would agree also that certain conditions be met for sugar to raise insulin, or indeed be problematic as I’ve described. I would assume Clearly there’s more to the mechanism than is being described here. Also, I don’t know that insulin itself is the only problem. When I did some “high insulin” experiments (eating the most “insulinergic” foods recorded in databases), I felt great. Ray himself has implied insulin can be good if I remember correctly (also if I remember Georgi correctly).
I’d like to know the mechanisms of action for excess sugar raising serotonin more specifically.
Would you try pure dextrose sugary foods as a crosscheck to your experiences with sugary sucrose (50% fructose) foods?
Good question. It would be a moot point as the glucose itself is found to push tryptophan in the bloodstream. In fact I was reminded of my issues, as people were describing problems on the protocol of glucose, so I think I may have found the problem.
It also gave me diarrhea. I’d be interested to know if people are getting digestive problems on the protocol… of course they may call it a herx reaction or detox
User: does too much sugar without protein raise serotonin
Peatbot: No, too much sugar without protein does not raise serotonin. In fact, sugar generally inhibits lipolysis, which decreases brain tryptophan and serotonin. This is contrary to the common belief that sugar raises serotonin levels. The anti-stress effect of sugar is partly due to its ability to decrease the availability of free fatty acids, which in turn reduces the brain's uptake of tryptophan and subsequent serotonin production.
thanks for the comment, @DavidPS
Unfortunately, "AI chatbots" are not true artificial intelligence; they just make outputs according to inputs. They don't have the brain to discern what's actually truly being said. They are all data no brain. Their results will always be inferior to a human doing the longform footwork thru the data themselves...
In this case, I'm positive I heard Peat say it... I could always be wrong of course, but I have zero faith in AI chatbots, because of the silly failures I've seen so many times on obvious fact problems.
I did a deep dive in to why I was getting headaches from too much sugary foods away from meals (after thinking I permanently cured myself of headaches with the Ray Peat approach), and eventually found Ray Peat speaking on this very subject; unfortunately, I don't remember the location or episode. Also, as I recall, I was not the only one that experienced this incidence, and it was on the rpf forum that I found it. The logic is sound, excess blood glucose pushes tryptophan into the blood, which raises serotonin; whole food proteins, or the right proteins as emphasized by TexugoDoMel, is necessary to avoid this. And, it may not have to be a lot of protein.
@ThinPicking agreed
@TexugoDoMel agreed, thanks for the studies.
I remember Ray Peat stating in an interview (I believe with Danny), that too much sugar at once without protein raises serotonin.
This is likely where the complications are coming from for some on this intervention.
Does anybody remember this, or have a source? We all know Ray was a fan of generous sugar consumption because of it's healing and pro-dopaminergic affect, but he also exercised nuance.
PS, I've got no problem with Dr Stephens, I think he discovered something Ray discovered about glucose metabolism and brain health long ago... Ray, however, had a more cohesive understanding of what's going on with the metabolism and brain, and suggested more than just sugar - nutrient cofactors, plus supplements like B3 and aspirin.
PPS Anyone remember those old posts from Georgi years ago showing case studies of reversal of mental illnesses with strait sugar consumption, or B3 supplementation? Anybody remember when Danny originally called his podcast evil sugar radio? I do. This didn't feel new the first time I saw it, and for RPF to jump on it like Dr Stephens has a unique profound discovery not already covered by Ray and the bioenergetic community, felt a bit disingenuous (like they can't admit Ray was on to more than they understood and they're just not super capable of contextualizing his broad spectrum of issues covered), or generously speaking, forgetful (probably the low vitamin A - hur dur).
Idk if you linked the same thread I’m thinking of, he picked up the work of essentially a Stalin-crime-denialist, whose political take was that Stalin was fighting western hegemony. Another version of the new world order conspiracy theory. I have no problem with it even if I disagree — He doesn’t approve of any communist/stalinist atrocities.
@thyroidchor27 and I believe urea can “detox” ammonia. Same with sodium benzoate found in the original glass version of Dr Pepper.
Peat said a little tobacco leaf (if you could get a quality source) under the lip throughout the day could be beneficial (I've yet to find 5 year aged and organic - I may just settle on organic).
If you don't know, drying removes the radioactive isotopes. And, tobacco is loaded with glyphosate.
Back in NotShanalotte's days this sorta thing didn't happen
@brad maybe I could trust you if you weren’t A JEW?