@LucH Thank you as always. I'll re-research Niacin to take note of possible factors. That RP forum thread you linked has another useful link to a Niacin discussion at the PhoenixRising forum: https://forums.phoenixrising.me/threads/does-methyl-absorbing-niacin-neutralise-methyl-supplements.54918/#post-919667
@PeatPerspective, you're very welcome. A steady dose of 50mg with most meals would probably bring much of the benefits we've read about Niacinamide, especially if you keep it up for a while. It makes for interesting research too, at the RP forum i do a title only search using the word Niacinamide, so many potential benefits are posted, especially by Haidut.