Posts made by Mulloch94

@aeblyve I don't think the antibiotic will help to kill covid. All the antibiotic will do is prevent an infection from covid. I was sick a week ago with a virus (possible covid, or the flu, never tested) and I got a pretty severe infection in the sinuses from it. I was blowing brown shit out, and got on some tetracycline to clear that up. That's basically all an antibiotic will do. But they're not good for killing viruses.

@aeblyve It's safe, there's been people who've taken upwards of 20 grams a day for long periods without adverse effects. It can increase bowel movements, and creates a watery consistency like diarrhea. That's when you know you've reached your limit and you should probably back off a couple grams.

@Marquis777 It's specific to the individual. Anyone with primary hypogonadism wouldn't be able to use that. He was also taking a lot of stuff. Vitamin E, B6, zinc, BCAA's, a mix of different proteins. You'd have to be strict about that too, doing it religiously everyday. Most people would probably just rather pen test and be done with it.

On a side note, the thread (if it still exists) where people were experimenting with putting pansterone on their balls had a lot of people report increases in T. I think IIRC someone even posted blood work of before/after.

I agree with libertarian economic theory. Inflation, federal reserve, fractional reserves, government fiat are all responsible for the decreasing of the standard of living. And all the autistic screeching from the left about raising minimum wages will just make the problem worse. We have a crises of economic illiteracy in the West.

However I don't think Mises or Rothbard got it all right. Both of them give really lackluster proposals for moralism. Utilitarianism and natural law are both wack shit in my opinion. Max Stirner is that chad motherfucker utilitarians look under their beds for before they sleep at night, lol.

I'm not, religion is for people who can't accept the slow moving train of science will one day answer the god equation.

But there's a far more fundamental reason why a large religious presence exist on forums. Most - if not all - forums are notoriously right wing. I mean FAR right.

That's because mainstream social media platforms are bombarded by progressives. And up until Elon Musk's takeover of twitter, they were mostly selectively targeted for removal.

And it's not like twitter is right-winged now, there's still MANY progressives voices on their platform, they're just less militant about removing people now. But twitter is just one platform. Most of the others are still heavily progressive.

I dislike progressives and fascists, so I've basically always been a nomad lol. In fact I dislike fascists more. Progressives are typically always idiots, and I don't find them threatening. People like Curtis Yarvin are intelligent and evil, and therefore a formidable enemy.

Calcium seems to ameliorate high BP not only through antagonistic effects to PTH but also preventing the release of aldosterone. Ray considered aldosterone a central factor in the development of heart disease.

https://www.mdpi.com/2072-6643/11/5/1112

"The link between calcium intake and blood pressure involves a connection between calciotropic hormones and blood pressure regulators. As was hypothesized many years ago, parathyroid activity increases the cytosolic concentration of calcium and increases vascular reactivity and blood pressure [113]. The effect of calcium intake on blood pressure is not shown in parathyroidectomized animal studies. Low calcium intake also increases the synthesis of calcitriol in a direct manner or is mediated by PTH. Calcitriol increases intracellular calcium in vascular smooth muscle cells. Low calcium intake stimulates renin release, and consequently, angiotensin II synthesis. PTH stimulates renin release, angiotensin II and aldosterone synthesis (Figure 3). We are willing with this review to promote discussions and contributions to achieve a better understanding of these mechanisms, and if required, the design of future studies."

@brightside said in Any experiences with DHT?:

@Santosh said in Any experiences with DHT?:

@brightside said in Any experiences with DHT?:

Best hormone. DHT > all others.

Clarity, energy, estrogen reduction, decreased inflammation and autoimmune like no other hormone.

It's not magic, but it's damn good.

It's even more helpful when you're actually sick, while T is much more hit-or-miss

How do you like it compared to Proviron ?

Haven't tried. I have tried Mast, though, and that was definitely interesting and different. Obnoxiously strong morning wood and erections, and I did see what people meant by mood benefits from Mast.

Have tried normal DHT as well? I've been curious to here people's testimonies on how masteron compares to normal dht. I have a small baggie of Mast P but never used it.

@Cerbrosyn I assume you're male? If the secondary male characteristics are something you wish to develop more then you should probably get on DHT. Probably a lot, like 100mgs twice daily. You should consult a professional probably, but my laymen opinion is even high dosages aren't particularly harmful. And you'll need the high dose for it actually start effecting male characteristics. Because anecdotally, I've experimented with low-dosages of DHT for quite a while and it does nothing except positively effect my mood. I did a high dose over 100mgs one time, and felt like a furnace so I never did it again, lol.

But there's been randomized controlled trials lasting upwards of 6 months taking 250mgs daily without any substantial adverse side effects. IN FACT...the real kicker is the main thing everyone worries about with DHT therapy wasn't an issue at all in this RCT. And in reference to another study of 37 men (not a RCT though) it actually improved prostrate status. https://academic.oup.com/jcem/article/87/4/1467/2374929

"In our study serum PSA concentrations did not increase during DHT treatment, and prostate size remained unchanged. Nevertheless, it is recommended that men using androgen replacement therapy should be carefully screened and followed up periodically."

"The results of a 1.8-yr survey of 37 men, aged 55–70 yr, treated with daily percutaneous DHT suggested that high serum levels of DHT effectively improved andropause symptoms while slightly, but significantly, REDUCING prostate size."

Again, I'd like to reiterate, even though DHT seems to be a relatively safe intervention course, you should definitely be under the consult of a professional of some sort. I think your major issues are avoided when opting for non-aromatizable androgens like DHT, but you could still develop issues like a high hematocrit, and you'd never realize it unless you're getting tests done. But DHT would be your best bet for correcting adverse development during puberty.

@jwayne I don't remember that person, thanks for the tip. I will look them up as well. I'm thinking about posting anything I find calcium related to this thread.

@Kinesyne said in Calcium for blood pressure:

@Mulloch94 https://www.amjmed.com/article/0002-9343(87)90268-3/abstract

Interesting paradox, I knew they prescribed calcium blockers a lot in preexisting heart diseases, my own mother had them prescribed for a little while. There's a pilot survey in those references that looks interesting. The group with essential hypertension had significantly less calcium intake despite both groups having similar potassium intake. Indicating calcium is possibly more potent than potassium at controlling BP. Which is interesting considering it's long been believed potassium is the most important mineral to control BP. I would like to see a controlled trial done comparing two groups, both with adequate potassium but one group also getting extra calcium.

@Peatly Thanks for citing that doctor's name. Yeah, I think the primary mechanism behind calcium's protective effect is it's suppression of PTH, which is also an independent risk factor for coronary artery disease. And since it can take years for PTH to finally rob your bones to the point of osteopenia or osteoporosis, it can sneak up on you, making you think you're "getting by" on low calcium intake.

@the-MOUSE Potassium bicarbonate would probably work really well. I've never used it before but the K in it would be absorbed really well. I get most of my potassium from fruits, meat, and coconut water. Just one 12oz tetra pack of coconut water has like 1 gram of potassium in it, so it's loaded with potassium. Potassium will help with fluid retention as well. I make my magnesium bicarbonate with mag hydroxide and carbonated water. I would venture to guess you do something similar to make potassium bicarbonate.

I think Ginger is relatively safe, and it's a 5-ht3 antagonist. I'm not sure what else would work, maybe mirtazapine? Wished that DaveFoster guy was still around, he'd probably be able to answer that more definitively than me.

Another tactic you could take would be addressing all the things that can promote QT prolongation or arrhythmia and working it backwards to minimize your chances of adverse effects with ondansetron.

What causes QT prolongation? Magnesium deficiency, potassium deficiency, androgen deficiency, progesterone deficiency, adrenaline excess, serotonin excess, estrogen excess.

So if you cant find a suitable replacement I would focus on getting plenty of potassium and magnesium in your diet. Coconut water is an excellent source of both, and you could also make Mag bicarbonate water for additional magnesium. Make sure your DHT and progesterone are at good levels. You probably won't run into any issues with a low-dose of ondansetron.

Probably thyroid, aspirin, and progesterone if you're going by a strict definition of a Peat inspired bioenergetic blueprint.

It begs to question though how many people actually follow it strictly. For example, Peat was never a big promoter of vitamin or mineral supplementation. Yet we've seen people taking mega doses of thiamine or magnesium.

Peat was never a fan of supplementing downstream hormones, yet we see people taking testosterone and DHT. I think most people, whether they admit it or not, follow a more interdisciplinary approach to bioenergetics.

I know I'm certainly that way. If I find someone else who says things that makes sense to me, I'll look into their work, and see if it can fit in my bioenergetic blueprint.

The acetylcholinesterase enzyme is tightly regulated, so I wouldn't expect a problem be associated with that unless you're taking something that inhibits it.

Is your serotonin and adrenaline high too? A lot of times acetylcholine, serotonin, and adrenaline will all be elevated together if someone is overmethylating. In which case, glycine or niacinamide can be a useful treatment course.

I doubt it, even in deathly sick people they can oxidize fat for fuel pretty efficiently. Add a tablespoon of coconut oil on something and eat it. The exogenous ketones from the oil should provide an energy boost if a ketone deficiency is the actual problem. What's more than likely is an electrolyte imbalance that happens frequently to people in ketosis. You need to salt the fuck up, and/or get a case of that Pedialyte water stuff. Or, ideally, just stop the ketogenic diet.

As some others stated BCAA's are going to be your best friend. Gelatin and casein would be two other good proteins as well. Boosting androgens and/or lowering estrogen will help modulate serotonin. I also think folate acts as a serotonin reuptake promoter, but i think I remember Haidut saying B9 was bad for some reason, can't remember why but you could probably find it on RPF search if Charlie hasn't removed it.

One of the more perplexing things the RPF has done in recent times is also become anti-calcium. Very weird, as calcium has literally been linked to longer lifespan in the elderly. More than that, I remember Ray Peat saying some researcher at the University Oregon (forgot his name, sorry) discovered a calcium deficiency was the main cause of hypertension, and not sodium excess. Well I have this study in my bookmarks that I saved, it sort of echoes that same logic and I thought I'd share it here with you all.

https://pubmed.ncbi.nlm.nih.gov/26126003/

"An increase in calcium intake slightly reduces both systolic and diastolic blood pressure in normotensive people, particularly in young people, suggesting a role in the prevention of hypertension. These results should be interpreted with caution, since the proposed biological mechanism explaining the relationship between calcium and blood pressure has not been fully confirmed. The effect across multiple prespecified subgroups and a possible dose response effect reinforce this conclusion. Even small reductions in blood pressure could have important health implications for reducing vascular disease.There is a great need for adequately-powered clinical trials randomising young people. Subgroup analysis should involve basal calcium intake, age, sex, basal blood pressure, and body mass index. We also require assessment of side effects, optimal doses and the best strategy to improve calcium intake."

Note that in this group they tested it on it reduced blood pressure even in normotensive young subjects. Meaning it could possibly be a useful intervention for people predisposed to high blood pressure before hypertension even starts. Preventing high blood pressure is critical to maintain the health of your kidneys and heart.

This seems like a pivotal point in human nutrition many people miss. I'm not one of those people who believes in the "perfect human diet." However I believe the best of human diets will consist of a generous amount of calcium, which is something missing in all these alternative "healthy diets" by a LARGE amount.

Plant based diets remove dairy, keto diets remove dairy, carnivore diets remove dairy, paleo diets remove dairy. Whether your diet is grain based or meat based, it's likely low in calcium. Heart disease is the leading cause of death in the country, and, I think, the world too. Hard to not connect these dots.

A truly healthy diet in my opinion would have some forum of rich calcium sources. Whether it be milk, leafy greens, molasses, figs, eggshells, etc. Conversely, a lower calcium diet can be managed provided you lower your phosphorus consumption. This would mean relying on more vegetables and fruits, and less grains, legumes, or meats.

I think 365 brand at my Whole Foods is okay. I'm not sure organic really matters with the juice, what's more important is making sure you got good ripe orange juice. The sour stuff is no good. If you want to make marmalade, then you need to use organic oranges because you're actually eating the peel.

Full disclosure I rarely drink orange juice, because the stores closest to me don't carry good stuff. And Whole Foods is like a 40 minute drive from me, so I'd rather find a replacement. Apple juice is a great replacement for me.

High dose vitamin C, at least 5 grams a day, preferably closer to 10. Taking around 2 grams 5x daily would get it done. It's important to not take it all at once though, because you can only absorb so much at one time. I'd space it out about every 3 hours. One or two aspirins dissolved in hot water and baking soda will help with the aches and fever.