Posts made by Mulloch94

This may be a situation where the anti-serotonin effects which are pro-liver cancel out to a greater degree the anticholinergic effects which are known to be hepatotoxic. Cypro's anticholinergicy is very weak to begin with, whereas it's anti-serotonin effects are very strong. One of the only approved treatments for serotonin syndrome in fact.

I'm not sure what to believe with regards to it's alleged effects on liver. There's been a long held conventional belief that cyproheptadine is damaging to the liver when taken chronically. I've seen some studies backing this claim up too. Nevertheless Haidut posted a case report of a woman healing what was supposedly "irreversible" liver disease with cyproheptadine, which basically is a complete about-face, lol. http://haidut.me/?p=1806

CICO matters. Ray seemed to agree with this as well, in one of the herb doctor interviews he told people to eat low-fat dairy to avoid the extra calories. He wouldn't have said that if he thought calories were a useless metric. There was some minority voices on the RPF talking about how CICO is dumb and that people should eating lots of calories to raise the metabolism or some shit. I always thought that was dumb, and I'm not sure where they got that idea because it didn't come from Ray.

Long story short, bring your caloric intake down. Focus on higher protein and higher calcium, both are thermogenic. Noting how important carbohydrate is, it would probably be best to cut the vast majority of your calories from fats. And a little exercise would help too. Not breathless exercise, but long slow walks, or lifting weights. Don't do the chronic cardio bullshit.

@latin said in Daily progest-E for 23 yo male safe?:

What negative reactions did you have to progest, and why do you think thyroid helped?

I would get really cold after only small dosages of progesterone. I think it was killing my stress response but I didn't have enough thyroid to keep my basal metabolic rate high. It may have also been liberating estrogens from my tissues, compounding the problem even more.

When I started to successfully implement thyroid I noticed a lot of my symptoms were gradually disappearing, but I would get these acute bursts of adrenaline that were very intense and unpleasurable. I don't exactly know what was causing that. I can only presume it must have been my thyroid and adrenals trying to establish a new equilibrium. I remember Ray saying that sometimes people will be more sensitive to adrenaline when they first start thyroid, but it levels out after you get your dose tailored correctly.

When I re-added the progesterone back in, it no longer made me cold. It would blunt the adrenaline response at a sufficient enough dose, and since thyroid will correct estrogen:testosterone ratios, it wasn't causing anymore estrogen symptoms like nipple sensitivity. All I had was what I like to call that "calm serenity" feeling, which can turn into a dopey feeling if you take too much P4, so it's important to get the dose right.

Also, this may vary from person to person, but as long as I keep my thyroid dose consistent, I don't need to do P4 daily if I don't want. I'd only do it on a especially stressful day, because once I broke that initial stress cycle thyroid is enough to keep my progesterone levels where they should be.

@latin said in Daily progest-E for 23 yo male safe?:

What dose were you taking?

I take 9-10 drops of progest-e. Roughly 30-35 milligrams. But that's not indicative of what you should be doing necessarily. If you're a man, my motto on P4 is to take whatever minimal dose is effective for the symptoms. For me that's around 30mgs. Which can actually start to be anti-androgenic, but I've notice it can still actually increase my libido at that dose. Weird, but I guess the anti-stress effect outweighs the anti-androgen effect and created a better erection for me.

@latin said in Daily progest-E for 23 yo male safe?:

I have t3+t4, but don’t know how to properly take it.

This can get tricky, lol. First I recommend measuring your temps, before AND after breakfast. Additionally, getting a TSH test will let you know more as well. Anything over 2.5 mU/L is definitely subclinical hypothyroidism. Emphasis on subclinical. Meaning docs won't diagnose you, but you still have the increased disease risk associated with hypothyroidism.

If your temps and tsh checks out, then I recommend taking thyroid the Broda Barnes method. Start with 1/2 grain and stay there for 3 weeks before taking more. Then up the dose to 1 grain, stay there for 3 weeks before taking more. Follow that pattern until symptoms subside. I use TyroMix, and I take it by mouth. This is important, because I see a lot of people thinking it's a transdermal product. With something like thyroid, you want to take it orally. Just put 3 drops in a small glass of juice or a empty capsule and take it.

@latin Maybe. You say it helps, so if it helps it helps. 1 drop is a very low dose too, so it's unlikely to cause problems at that dosage. But some people do react poorly. I didn't tolerate progest-e well until I got on thyroid. And getting thyroid to work for me was a process in and of itself. As far as "messing with your hormones" there's simply no chance 1 drop would alter your hormonal profile. Men usually don't start experiencing the anti-androgen effects until they get over 20mgs.'

Have you had any blood work done? A greater question to answer would be why is the progesterone helping with these things? You're 23 years old, so presumably you shouldn't be deficient in the youthful hormones. Perhaps the additional progesterone is triggering a GABA response. And/or it's lowering adrenaline which is well known to cause insomnia, anxiety, and depression (look up Dr. Platt's work on adrenaline dominance).

Are you hypothyroid? Are you hypogonadal? Do you take stimulants or consume large amounts of caffeine? Do you take SSRI's? Knowing your TSH, prolactin, & estradiol could help determine if there's some sort of depressive effect occurring in your HPTA.

@mostlylurking I think I probably used a poor choice of words when I said the conservative party. Conservatism is more of a social movement than anything, so yeah I think conservatives will more or less be the same post-Trump. If you think about some of the archetype examples right now, conservatives dig that whole homestead, homeschool, family unit lifestyle. That existed before Trump and that will exist after him. What I meant was I think it will be really hard to keep establishment shills out of the GOP party when he's gone. Rewording it, I think the populist political wave will begin to die down some when he's gone. I don't know any other conservative right now with the capability of tapping into that energy.

Ron DeSantis totally fucked up in the debates, and I don't think MAGA crowds see him as being capable of national leadership anymore. He also seemed to be more pro-war than I thought, and perhaps if he were in the oval, he might just be another Raytheon elephant and therefore not so anti-establishment. If there's one thing I did like about Trump above all else, he stood his ground on foreign entanglements...more or less. I mean he increased a few drone strikes here and there, Yemen especially. But that was more or less him throwing a bone to the military-industiral-complex so they stay satiated on innocent blood and not give him the JFK treatment. But he didn't increase any substantial war efforts. Ever since Biden got in we've turned that shit up ten fold, lol.

Thought I'd share a nice "metabolic" pancake recipe I've been eating off and on for the past several months. It tastes basically like traditional bisquick pancakes to me, with the only difference being a lack of fluffiness.

Recipe (for 2 cakes):

1/2 cup rolled oats
2 whole eggs
1/2 tsp eggshell (or calcium carb)
1/4 cup of casein
3-4 tbsp of milk
pinch of ceylon cinnamon
pinch of salt

Directions:

1. You can skip this step if you want, but I like to first soak the oats in water overnight, then I dehydrate them.

2. Then put oats in a coffee grinder or a comparable pulverizer to turn them into a flour.

3. Crack the eggs into a bowl and whisk thoroughly. Then add all the dry ingredients to the bowl. Slowly begin to incorporate the dry ingredients with the eggs.

4. Begin to add the milk a couple tablespoons at a time until you're able to whisk the mixture into a thick batter consistency.

5. Now you can cook them! In a preheated pan add a little coconut oil and pour enough in for at least one cake. If you have a pan BIG enough you could go ahead and cook both at one time. My pan is only big enough for one at a time. About 3-4 minutes each side. Top with maple syrup or whatever you want to use.

Some footnotes:

I've tinkered with the recipe a lot, and if you like them I urge you to as well. For example, one time I didn't add any sweetener at the end, but I added apple sauce to the batter. Really good! If you can't get over the lack of fluffiness, you could also probably add a couple tbsp of self-rising flour to the oat flour and that may correct the issue. You could also experiment with different proteins. I recommend casein though If you can tolerate it. It has the lowest tryptophan, methionine, and cysteine content. BCAA's or collagen may be good alternatives.

@Lizb Thanks for the insights. I haven't been doing mine long, only about 5 weeks now. But it's became a viable replacement for bag breathing, which I never really cared for anyways. I'm still confused about all the various methods. For example, I've been doing the "breathe light" method and the "nose hold" method. I actually temporarily stopped these past few days due to a sickness I had, my nose and sinuses were stuffed, and it wouldn't have made for a very therapeutic experience. But hopefully I can start back tomorrow. It was really a breakthrough when I first started, helping me with my chronic hyperventilation (along with thyroid supplementation). I'm not sure I understand to the fullest extent what you mean by cleansing reactions, because the Youtube videos I've been watching on Buteyko hasn't mentioned anything about it. I did, however, notice my sleep was worse for the first couple weeks I did it. I'm still very much in the process of determining whether this practice will work for me or not, but so far the side effects have been mostly positive.

@Ruben Maybe if you have a deficiency. Copper is very important for normal metabolic function. It's needed for thyroid hormones and the electron transport chain. Copper can also keep histamine from getting too high. There is however some things that aren't so good about it. It synergizes with estrogen, and is estrogenic itself. It's also an adrenaline agonist. Probably not something you'd want to supplement with unless you can confirm a deficiency with blood work. Otherwise just get it through good diet.

That's awesome you're feeling better now. I'm glad you didn't get sucked into the toxin A cult. I don't know anything about your particular genetic condition, but having a predisposition to a vitamin A deficiency would make something like a retinal detox all the more dangerous.

@oldchem Haven't seen that guy in forever! Well he's definitely put on some weight, lots of face fat. Which usually means fluid buildup. People who eat a lot of junk food always end up swollen because of that lack of potassium. I bet if dude went on like a fruit fast or potato fast he'd piss buckets out!

@mostlylurking Ehhhh...I think conservatives are more opened to discourse of opinion on wedge issues, but when it comes to the bare essentials they're just as lockstep as the liberals are. The republican party is basically the cult of Trump. Look at what happens whenever those "Never Trumpers" try to shill for a new candidate....they get crushed, lol. The red wave is a Trump wave. And once Trump leaves politics for good, the conservative party will go back to being just as lame as ever with dinosaur establishment shills like Mitt Romney and Jeb Bush.

Interesting testimony, keep us posted I'd be curious to know if the intolerance stays away. It actually sounds a lot like Danny's experience as well. Not sure why so many people just choose to accept food intolerance rather then search for a way to address them. The gut-thyroid connection is well known, not just in bioenergectics. The antibiotic thing is not so known though, lot of dogma in the alt health spheres push people away from antibiotics. So I guess it's something they don't think of. Or maybe they stumble upon it by accident, as in your case.

@Kvothe said in Mild Vitamin A deficiency decreases DHEA and Pregnenolone by 40%:

@Mauritio You are stuck on bad science Georgi Mauritio which is harming the people. I know you have a good heart and would not perpetuate this fraud and slow genocide of the people if your eyes were opened. I pray for the scales to come off your eyes, in Jesus name.

Bad science according to who, the prophet Charlie? I've never seen a group of people so gullible before in my life. The toxin A crowd is about 6 months out from castration territory...then comes the cyanide in the apple juice, you know, for detox bro

@pannacottas I used 50mgs in one teaspoon. I take around 30mgs of progesterone in a single dose, give or take (Progest-E's dropper isn't exactly percise.) But since a teaspoon has about 100mgs, I made it where each dose would be roughly 30-33mgs of P4 and 15-17mgs of T. Of course you can extrapolate that figure out to the whole bottle if you wanted to. I didn't, because it was my first time trying it and I didn't want to ruin a whole bottle of progest-e if I didn't like how a P4:T combo felt. So I just started with a teaspoon. The T dissolved nicely in a hot water bath and stirring. Turns out I liked it, raised my libido more than just androgens by itself. Basically I think anyone who responds well to Haidut's CoritNon (P4:DHEA) will respond well to P4:T.

@Lizb What was it about buteyko breathing that made you consider it dangerous? Personal curiosity, buteyko is something I practice daily, and would like to hear from others who didn't have a good reaction to it.

As for Charlie's cholesterol drop it's anyone's guess. But more than likely I would bet it had something to do with him avoiding vitamin A, and thus it liberated stored A which is then combined with LDL to make pregnenolone, DHEA, DHEA-S, etc.

@pannacottas I've gotten normal T to dissolve in progest-e before. The DHT I had wasn't micronized, so I was afraid it wouldn't dissolve well.

@Kvirion said in Why is the Ray Peat community so far right?:

I assume that the problem is more complex than a one-dimensional left-right axis.

It certainly is. In fact, I've increasingly been developing a new opinion that the left-right axis means essentially nothing in today's sociopolitical culture. The waters become even more muddy when you throw political parties in the ring too. As meaningless as the left-right axis is, democrats and republicans are even more meaningless. For example, all American democrats are right-wingers. More or less. Take all their social culture BS out of the equation for a second, because being a leftist has nothing to do with any of that. Do democrats support labor or do they support capital? The answer is definitively the latter. Republicans, also right-wingers, but far more radicalized in the sense they have a strong push toward national independence, which is naturally at odds with the establishments quest to further the globalization of capital.

Naturally MAGA bros lack the "intellectual refinement" that their Occupy Wall Street predecessors had in the early 2000s. But that's too be expected, the OWS movement was mostly anarchists, smart ones too, like David Graeber. As much as I disagree with Graeber's economics, he understood power dynamics very well. The MAGA movement doesn't understand power dynamics well, but they do recognize corruption and know how to point at it, lol. The big difference is anarchists did it in the 2000s out of loyalty to labour. MAGA's anti-globalism is out of loyalty to the nation-state. In this light, we could see the democrats as being a party slightly more capitalistic than even the republicans. America doesn't really have a left-wing option. And since America doesn't recognize absolute property rights, they don't have a libertarian option either.

So this two headed axis is very useless in my opinion. We're not even getting into all these little micro nuances either. Like urban liberals vs rustic blues. As soon as you get out of any major Big City shit-hole, most people, even democrats, own guns. Likewise, I've seen examples of traditionally very conservative practices like church becoming woke for LGBTQ or other groups in the inner cities. What were seeing here, in my opinion, is that environment is superseding anything people believe politically. And I think this is where bioenergetics slips into the equation. Might also be why someone like Ray Peat was never really pinned down by a particular political ideology. There's this old saying that "culture is upstream from politics." If that's true, and by all accounts it is, then bioenergetics is the source.

@thyroidchor27 Hating Women??