@PranaDeva said in Chris Masterjohn: Salicylates are Toxic:
Danny Roddy has some tips for safely using aspirin: ---
Hi, I didn't read DR's tips. An excerpt would be appreciated 😉
I won’t begin taking daily aspirin at the autumn. Whatever the dosage may be: 81 – 350 or higher dose (500-1000 mg). The impact on platelet aggregation is concerned. Long term use is different. The body counteracts / adapts its production.
Why?
A low amount of platelets is dangerous with Sars-Cov-2 when the immune system over-reacts.
Source: European Medicines Agency (EMA) / Herbal Monograph on Salix purpurea / other Salix spp. Cortex.Page 36–37 (Discussion) of the PDF. *
Chemically and pharmacologically, salicin (the main pro-drug in willow bark) is converted to salicylic acid and does not contain the acetyl group that allows aspirin to irreversibly acetylate COX-1 in platelets. Because of that, willow/salicin does not produce the same aspirin-like irreversible antiplatelet effect — clinical and regulatory reviews report little or no aspirin-equivalent platelet inhibition with standard willow bark extracts, and when inhibition is observed it is markedly weaker than with aspirin.
👉 https://www.ema.europa.eu/en/medicines/herbal/salicis-cortex
Scroll down to “Documents” → click
“Assessment report on Salix (various species)… 31 January 2017 (PDF)”.
This is a free and public document (no login, no paywall).
That PDF (about 47 pages) is the full European regulatory review of willow bark (Salix cortex).
