Posts made by LucH

@yamnayan said in Sudden lactose intolerance, need help.:

Could this be from a sudden increase in sugar? I did sugarmaxx like a retard. I have a feeling that I might have nuked my metabolism drinking a shit ton of diet coke before discovering peat. Replaced that with normal refined sugar and a coke here and there. Will look into that as well.

yes, but you have to understand this point:

• Too much / too frequent of one thing is going to impact the kind of predominant bacteria. So, what was well balanced is going to change.
• excess refined sugar is going to deplete thiamin. Interaction between B1 B2 B3 and B8. Brown sugar cane is a misfit. Not really complete. Muscovado is better but the taste is different. I Have 3 kinds of sugar at home:
  => muscovado, coconut sugar, brown cane sugar.

• occasionally sugar beet (white sugar) for pastry / cakes, and pure Via (a mix with stevia and erythritol). Note that all polyols have a bad impact on microflora and help fermentation if repeated use. But this one is the least negative.

• if you eat manufactured food (not the whole element found in nature, completely processed), you eat on a devitalized way. Lacks are repeated.
  Note: Don't take a B50 supplement on a regular basis. Not the right posology: cancer growth stimulation). RDI or uptake above 90 mg B1 HCL. I take 100 mg B1. Need to be developed elsewhere.
• Diet coke contains edulcorates. Impact on the microbiota. Like every kind of drink with edulcorates.
• When taking repeatedly the same foodstuff, you must know / study the possible side effects.
  Suggestion:
  Use collagen powder for half of your protein if you have problem, if you can't manage with bone broth.
  Too often eggs could give an immune response. OK for 2 or 3 times 2 eggs.
  You could mix lentils or peas with rice to get a full spectrum of amino acids.

@Sugarnotsnow

I decode:

1. 2.6 and 1.3 year benefit (with 2 kinds of measure).
2. DNAmAA did not statistically differ between participants.
3. Therefore we concluded vitamin D supplement is associated with lower DNAmAA with vitamin D deficiency.
   My reading:
   How the hell can they say 2 different things in the conclusion! (no statistically difference and lower methylation of DNA).
   A clue: The sponsors of the study are also the financiers. They will only read the conclusion.

Blood sugar and carbohydrate absorption speed
Source: Montignac > blood sugar > Physiology of intestinal absorption
Not all carbohydrates are absorbed in the same way: 400 K/cal. of lentils is not equivalent to 400 K/cal of potatoes. For the same amount of carbohydrate, consuming lentils provides three times fewer available “calories”.
Figure 1: Carbs absorption speed (with food stuffs)

Credit : http://www.montignac.com/fr/sucres-lents-sucres-rapides/

There is no slow or fast sugar. This is a misconception!
Figure2: Carbs absorption speed (with sugar types)

Green spot: disaccharide (sugar cane, honey)
---: Polysaccharide: starch
==: (blue spot): monosaccharide (glucose & fructose)
Note: Milk and yoghurt are special cases (growth homone).

Useful link (in French, excerpts from the book) (with pictures to illustrate the comments)
Book : Glucose Révolution – Jessie INCHAUSPÉ
https://mirzoune-ciboulette.forumactif.org/t1925-glucose-revolution#26942

• “food order and postprandial changes”: The ideal order of foods: fiber – proteins (with fat) – carbohydrates. The fibers ingested first considerably reduce the glucose peak caused by sugar.
• Learn how to smooth the blood sugar curve, with examples. This way you can better manage possible weight gain or lost energy capacity.

@RPadmirateur said in How to stabilize blood sugar during COVID illness?:

too much T3 can also lower blood sugar too much, spiking cortisol and epinephrine.

I won't say it so.
When more T3 is used, it burns more benzine. Probably / logically if you tell the engine to speed up.
So the uptake of sugar must be in adequation, Rather available immediately (glucose and glycogen if your liver functions well). With fibers and fat from food when eating carbs to optimize the flux.
But if it's OJ, yoghurt and corn flakes, you'll have soon after (1-2 hours later) a problem: Cortisol secreted. Cortisol is used to degrade muscles and get fuel (carbs).
And by the way, it's not when adding 1 tbsp. sugar cane in your morning coffee you're going to solve the problem.
In process (come back).

@RPadmirateur said in How to stabilize blood sugar during COVID illness?:

I am wondering about how to stabilize blood sugar while sick with COVID.

Need extra vitamin E ( minimum 2 tocols) for 2 weeks to fight properly Covid.

Here is useful info on the management of glycemia
https://mirzoune-ciboulette.forumactif.org/t389-index-glycemique-des-laits-vegetaux#3017
Note: In French (translator needed) but there are links in English (sources).

• GI of cow milk and vegetable milks
• Understanding glycemic index (GI) and glycemic load (GL).
• Low sugar and quick sugar: false concept
• Impact of milk and yoghurt on insulin spikes
• Potassium and impact on glycemia + Diabetes
• RP’s article explained: “Glycemia, starch and sugar in context”
• Calcium absorption rate
• Dress your carbs: Why food order matter.

Direct links to the post (same post)

• Potassium and impact on glycemia
  https://mirzoune-ciboulette.forumactif.org/t389-index-glycemique-des-laits-vegetaux#25572
  => Insulin and potassium relationship. Potassium and Diabetes: Understanding its Importance.

• translated excerpt from RP: Glycemia, starch and sugar in context.
• Cortisol & glycémie: Le cortisol comme chef d’orchestre

• Analysis of different kinds of milks
  https://mirzoune-ciboulette.forumactif.org/t389-index-glycemique-des-laits-vegetaux#28407
• Calcium absorption rate
  https://mirzoune-ciboulette.forumactif.org/t389-index-glycemique-des-laits-vegetaux#28412
  => Ca absorption is dose-dependent. Calcium bioavailability from different sources.
  => How is Ca absorbed (graph): Link between hormones, vitamins D and K2 and calcium.
• How is your breakfast with flakes or oat impacting your daily management of glycemia.
  https://mirzoune-ciboulette.forumactif.org/t389-index-glycemique-des-laits-vegetaux#28608

• Graph. And link towards Jessie Inaupsché book.
  => Dress your carbs.
  Example: A breakfast that moderates the blood sugar peak has a positive influence on insulin management for the rest of the whole day!

• Why food order matters
  https://mirzoune-ciboulette.forumactif.org/t389-index-glycemique-des-laits-vegetaux#28711
  => Vegetables first – meat (with fat) – carbs. + Graphs.

@yamnayan said in Sudden lactose intolerance, need help.:

Seriously confused and no idea what’s the problem here. Help would be appreciated.

Hi,
You're not going to appreciate my proposal:
Listen to your body, at least timely / temporally or you won't be able to drink milk any longer. Your immune system is going to mark it as an intruder.
No matter why at the moment.
If your digestion is insufficient we can make suppositions.
The amount of lactase enzyme is temporally insufficient. Probably not the case, with a short delay. But the conditions (Ph) and the context have changed (flatulencies).
Perhaps you were able to drink a kind of milk from a region (type A ><B), if you've changed.
Too much liquid makes it harder to digest proteins too. These ones require a acid milieu.
There are other reasons. (...)
If you have gas, you may suffer from dysbiosis (fermentation). Not the adequate flora.
When giving too much of a kind of macronutrient, you change the balance in the microflora.

Diarrhea is a way to avoid what doesn't suit to the situation. irritation or inflammation.

No matter why. Try to avoid 2 or 3 days long in order to recover a normal transit.

Then take time to adapt, progressively.

And don't tell me you were able to eat so and how much before the crisis.
Not very clever as argument. Adapt to the new situation or you'll be "punished" like a child who doesn't want to listen to one's parent, who doesn't see farther than the corner of his nose.
Sorry to say it so, but it has to be put forward.
Take care of you and learn to listen to your body signals before it's too late.

@the-MOUSE said in whats your opinion on taking kefir?:

He also highlights the potential for kefir to contribute to an overproduction of lactic acid, which he associates with inflammatory conditions and stress on the body.

It's a matter of quantity and frequency.
1° Drop the liquid in the yoghurt before eating.
2° I take 100 mg thiamine at breakfast and midday when eating once a day Greek yoghurt.
It helps neutralizing lactic acid.
3° I make breaks between two pots 1 kg / 2 pounds (10 % fat). Yaourt has an impact on the intestinal flora.
=> Need to be balanced with polyphenols (raw vegetables) and meat to diversify the flora.

Final thought: RP is probably right. Nobody is perfect. but if you enjoy it and knows the limits of what you're doing, you shouldn't feel "guilty", provided you metabolize well / you don't have problems with histamine and or digestion.
I repeat: once a day (150 ml / 5 oz.), with a break between 2 takes. At least a break 1/3 of the time.
Not a "scientific" answer, I know. But what about the pleasure of eating, provided you can manage it! I put blueberries or cut strawberries and 1 tbl brown maple syrup, at breakfast. Scandal again: berries + fructose. ( histamine and tiny seeds in strawberries).
Should we stop drinking one glass of wine (125 ml / 4 oz.) because there is ethanol in it. The liver stops all the processes when ethanol arrives. Not every day, of course. The weekend or a break when the bottle is empty (3 days long).
As far as kefir is concerned, I'll limit fruit kefir (acidity) to 30-50 ml. Milk kefir is less acidifying but still bringing the same quantity of lactic acid, I suppose.
Not so interesting as pointed. Vary and make pause / staples.

@AlphaCog said in Metformin reduces gluconeogenesis that is typical of "fight or flight" stress.:

Fructose is elevated in the brain of patients with AD
Sorbitol and fructose levels (both components of the polyol pathway) were significantly elevated, averaging 3–5-fold higher in all regions of the brain studied, including the hippocampus, entorhinal cortex, middle temporal gyrus, cingulate cortex, sensory and motor cortex, and cerebellum.

Agree on the observation but most diabetics take sweeteners. Polyol family. The liver has limited capacity to process polyols. Supposed to be considered residue, not to mention fermentation issues and the impact on the microbiome. No wonder in the long run there is an impact on the brain.
RP considered fructose as a balancing and metabolic element provided that there is a balance between fructose and glucose and that we remain under 50 grams of fructose. 25 gr in case of liver problem (and therefore diabetes).
Conclusion: this kind of study doesn't prove anything for me if the parameters are off the line.

@AlphaCog said in Metformin reduces gluconeogenesis that is typical of "fight or flight" stress.:

Association between Metformin Treatment and Improved Symptoms of Post-Traumatic Stress Disorder

One side of the problem.
Side effects of metformin
Haidut has posted:
The main first-line of therapy for diabetes II is the drug metformin, which happens to be a potent inhibitor of complex I of the electron transport chain (ETC) and as such is likely to drastically increase ROS levels as well as lipid (PUFA) peroxidation. Luckily, the pro-dopamine and anti-serotonin drug bromocriptine has also been approved by the FDA for diabetes II treatment and is a much better choice for both diabetes and AD.
Source:
PUFA/endotoxin cause Alzheimer Disease (AD), the plaques beta-amyloid/tau are protective
https://bioenergetic.forum/topic/2845/pufa-endotoxin-cause-alzheimer-disease-ad-the-plaques-beta-amyloid-tau-are-protective/1

@fruitfly said in Vitamin K and constipation:

Does anyone know why?

Saturation has been reached. The dose must be adapted.
Attempt for a clue: In short, too much of a good thing is bad. What is not used leaves quinones.

Too much quinone is not advised. Quinones generate reactive oxygen species through redox cycling.
Excess K2 could have an impact on feces (constipation or diarrhea). When taking a supplement high dose, what is not used remains as quinones and must be neutralized by the liver.
Too many quinones could interfere with hormesis. Too much of a good thing is deleterious.

Info on absorption, target and dosage of vitamin K (and links from Chris Masterjohn and Kate Rheaume-blue) (in French, with English links)
https://mirzoune-ciboulette.forumactif.org/t1704-vit-k-mk4-vs-mk7-update-02-2020#21497
Excerpt:
Vitamin K uses the same pathway as Vit E
Does vitamin K supplementation deplete vitamin E?
Mito has said on RPF:
There are several aspects of vitamin K’s biochemistry that suggest high doses vitamin K could have adverse effects on our health:
• Vitamins E and K are broken down in similar pathways (Shearer, 2008). High doses of either one elicit an increase in these catabolic pathways by activating a common receptor known as the steroid and xenobiotic receptor (SXR) or the pregnane X receptor (PXR). As a result, high doses of one will elicit the destruction of the other. Thus, high-dose vitamin K could contribute to vitamin E deficiency.
• Second, a small portion of vitamin K is broken down to a compound known as menadione (Thijssen, 2006). Some of the menadione is used to synthesize MK-4, but high concentrations are toxic. We therefore conjugate a portion of the menadione to glutathione, the master antioxidant and detoxifier of the cell, and excrete the complex into our urine. High doses of vitamin K could therefore deplete glutathione. This would impair detoxification, and along with vitamin E depletion it would hurt antioxidant activity.
• High doses of vitamin K can inhibit bone resorption, which is probably the mechanistic basis by which 45 mg/day reduce fracture risk (Iwamoto, 2013). While bone resorption sounds like a bad thing, we need to use it every day to help our bones remodel themselves and adapt their structures to our lifestyles, and to keep blood levels of calcium within a precisely controlled range. We also use bone resorption to release osteocalcin into the blood, where it acts on multiple tissues to improve our metabolic and hormonal health (Ferron, 2007; Oury, 2013). Ironically, one of the benefits of vitamin K2 is to support proper production of osteocalcin, but high doses of the vitamin could hypothetically prevent us from using it. That would be expected to hurt blood sugar control, insulin sensitivity, our metabolic rate, and, in males, testosterone production.
Reference: Chris Masterjohn – the Ultimate Vitamin K2 Resource. 2016

@secondkelping said in Reintegrating Starches (Peat Success Story):

Anyway, I started eating that almost everyday, and at first, my digestion wasn't perfect but it slowly improved.

Was it bloating, with gas (stools) or "simply" long digestion?
Details are needed on the symptoms if you want an clear advice: time, way, amplitude, where symptoms, description.

No, for D3, if you get the right amount of magnesium (350 - 420 mg). Too short or too much could impact the assimilation. PUFA inhibit the absorption of vit D (nuts, oil from sunflower, corn, soya)
But of course there is much more than D3 vitamin in the sunlight.

• Excess magnesium can hinder the absorption of vitamin D. Neither too little nor too much magnesium (RDA is favorable).
• If the ratio PUFA : MUFA > 1, you will have difficulty increasing the levels of 25(OH)D. This brings us directly to 18-20g and 12-15g of PUFA consumed daily by American men and women (Kris-Etheton, 2000) and their negative impact on the absorption of already low quantities of vitamin D in food. So beware of manufactured foods which often contain an addition of soy and corn oil.
  By the way, if your sun shadow exceeds your height, you will not make vitamin D. Question of wavelength.

For other readers:
Useful link (in French, translator needed, but with links in English):
Absorption de la vitamine D insuffisante ?
http://mirzoune-ciboulette.forumactif.org/t1664-absorption-de-la-vitamine-d-insuffisante#20619
Facteurs qui facilitent ou contrecarrent l’absorption de la vitamine D3

@ricksaban said in emergency, need help from peaters plz:

I got bit by some insect the other night on my upper lip of all places.

Always have 10 essential oils in your luggage.
Here lavendula aspic.
Try to find a phytopharmacologist.

@schemingfonzie said in Potatoes, gas, constipation:

But what underlying problem would cause me to react so poorly to starches? Too much bacteria?

Reply

There are 2 kinds of starch in potato, one kind of which can't be degraded by our enzymes but well by bacteria.
When the transit is weak there is proliferation.
Insoluble fiber has nothing to do in the second part of the colon. Otherwise, there will be problems if too frequent.
We have still to determine the type of fermentation Fermentation or putrefaction (sulfur odor, like stinky rubbished eggs, in the last case).
See Dr d'Oro (Swiss Dr) i you want to go deeper in the test to understand the different types of gas (sulfur or hydrogen).
But if you feel a bit better when not eating potato, than with eating rice, the problem is to be considered as a fermentation dysbiosis.
Practical consideration:

• Improve transit: 2x / d, to avoid stagnation.
• Take care of MMC (interprandial digestion)
• Clean the place (cure with essential oil, but it has to be done on a special way to reach the second part of the colon). I've done it as if it was the beginning of a SIBO/SIFO.
• Afterwards occupy the place (new probiotics).
  I can give a link to my log where I had to deal with excess histamine and bacterial overgrowth, if you are interested.

Vocabulary: MMC (Migrant motor Complex)
Prokinetics and Intestinal Motility
Dr D’ORO (Swiss Dr)
Mechanism of prokinetics Prokinetics are products, either natural or medicinal, that stimulate and coordinate intestinal motility, making it more effective. They act on various receptors in the intestine, thus allowing varied mechanisms of action. Some prokinetics inhibit dopamine which acts as an inhibitor on the digestive system. (…) Other substances also act on acetylcholine receptors which is a stimulating neurotransmitter of the intestine, other substances act on antagonistic (5-HT3) or agonist (5HT4) serotonin receptors. Etc. Thanks to these combinations of action, prokinetics have the capacity to amplify and coordinate muscular contractions of the intestine. They can act on different sites of action, both on the upper part of the digestive system such as the stomach or the small intestine and on the colon. Prokinetics can improve gastric emptying by coordinating the closing of the lower esophageal sphincter and the opening of the pyloric sphincter while the stomach contracts. They are known for their ability to stimulate the migrating motor complex (MMC) to clean the small intestine of this waste. Certain prokinetics have the ability to improve intestinal transit and can be used for example during constipation. However, prokinetics should not be confused with laxatives. (…) We will see that there are natural or medicinal prokinetics.
Note: I’ve used Resolror 0.5 gr as prokinetic.

Source for MMC info (Migrant Motor Complex) (=> interprandial motility)
“The complexity of the relationships between motility, transit and absorption is mainly due to the numerous parameters which characterize an intestinal contraction and to the nature of the intestinal contents.” (1)

1. Role of motility in intestinal transit and absorption
   J Fioramonti 1, L Buéno. Presse Med. 1989 Feb 15;18(6):249-54.

@wrl said in Period Cramps remedies for my gf:

Menstrual Cramps/PMS

100 mg B1 has proved to be efficient when suffering from PMS.

Comment: More efficient when taken just before. Morning or midday, right before eating.
There are other things to take into account to optimize:

• magnesium bisglycinate 300 mg x 2 or 3 (with food).
• zinc if not eating red meat (15 mg)
• gingimber could be tried: 250 mg extract (powder) at the beginning of the period, then every 6 hours.
• Ibuprofen is the only AINS to fucntion (against prostaglandins). every 4 hours during 2 or 3 days. 4 times a day. But it's going to overload the kidneys. A hot water bottle could do just as well.
  No aspirin (fluidity exacerbated) (unless you take Vit K1)
  Source (in French):
  https://helloclue.com/fr/articles/crampes-et-douleurs/crampes-menstruelles-leurs-causes-et-les-moyens-de-les-soulager

Useful info :
La lutéine est prédominante dans le cerveau
https://mirzoune-ciboulette.forumactif.org/t1702-vous-voyez-flou-des-taches-apparaissent#25944
Type de caroténoïdes et efficacité antioxydante (AO):

@Strider said in Need help with significant eye injury:

I've been taking Prog/Preg/DHEA since the injury, and that probably played a role with restoring some eyesight when the initial prognosis was that i'd be blind.

Hi,
I’ll take a supplement as antioxidant to dampen possible inflammation, having the capacity to cross the retina barrier, as astaxanthin. 2 x 4 mg daily, with a meal with some fat.
Lutein and Zeaxanthin are more specific for eye retina. In cure 2 or 3 weeks. Then stop a month. Begin again once only if you’ve seen improvement.

@mostlylurking said in Reintroduced Wheat - Confused With Results:

I have recovered my health via high dose thiamine hcl (and magnesium glycinate). My digestion works great! My food allergies are all gone. My inflammation is a thing of the past. Many health issues have resolved, including scoliosis.

@mostlylurking
Great post. Thanks for the links.
Indeed a deficiency in thiamine has a huge impact on the brain-stomach axis through the vagus nerve.

@tk
There is a strict protocole to follow when supplementing thiamine. Read the links before starting.
To summarize overton main ideas (nutritionist): B1 Thiamine protocol
Mega-dose of thiamine: beyond the resolution of "deficiencies"

• By saturating the cell, you can bypass the low affinity and restore the enzymatic function in its normal state. (=> Justification for the use of megadoses). Some people do not suffer from what we call a nutrient deficiency but from a metabolic block (blocked enzymes)
  https://mirzoune-ciboulette.forumactif.org/t2045-english-corner-anti-stress-neuro-protective-effects-of-thiamine-b1#29728
  Active and passive diffusion. Capacity of certain forms to cross the encephalic barrier. Supra-physiological contribution. Interaction (diagram) and example of dosage.

*) This could be a game changer!
https://mirzoune-ciboulette.forumactif.org/t2016-this-could-be-a-game-changer#29423

• Pharmacological dosage of thiamine
  Target for high dosage:
  B1 300 - 350 mg 2x/dy
  B1 => Towards 750 mg 2x/dy (in 3 steps)
  B1 => then 1 gr 2x/dy according to Dr. Costantini
  His protocol (with potassium) :
  https://highdosethiamine.org/hdt-therapy/
  2 gr of B1 per day, before and after the lunch (Midday)
  NB: We do not increase the dose until the discomfort has regressed in the event of side effects.
• Read the references given in this post, particularly the references 10 - 11, notably Dr. Allil Overton.
• You will need Mg. 380 - 450 mg of Mg element to activate thiamine.
• Dosage of Thiamine HCL. Contraindication.

*) Original text (source)
How to Apply High-Dose Thiamine Protocols in Clinical Practice: Part 2
Practical Guidance
https://www.youtube.com/watch?v=RFZUzS_xP9A
EONutrition – Elliot OVERTON speaking (nutritionist) (multiplex) – Part 2 – Video 2:04:02
This is the second of two lectures I gave (Dr Overton speaking) to a group of medical/health professionals on the clinical application of high-dose vitamin B1. In this video I outline the difference between nutritional deficiency and the concept of "functional dependence". I then discuss the practical aspects of forming a protocol including: - Which form to use and why - How to dose for different conditions - When to use this therapy and when not to use this therapy - Managing patient side effects.
*) 10 hallmarks of the video

1. 07.059”: Basic Definitions
2. 08.21”: Nutritional Deficiency
3. 08.40”: High Calorie Malnutrition
4. 11.12”: Functional Dependency
5. 29.49”: Symptoms of B1 Deficiency
6. 32.22”: Therapeutic Use of B1
7. 34.40”: Forms of Thiamine Can You Use
8. 45.05”: Peripheral Neuropathy
9. 47.12”: Disulfide Derivatives
10. 49.47”: Heavy Metal Chelating Ability

11. ---

@reasonablepete said in does butter oxidise when used as cooking oil?:

This would be the case for any cooking oil that is not particularly stable under heat, like butter. That is probably why coconut oil is preferable.

Yes indeed.
Butter is 82 % fat:

• 65 % SFA
• 30 % MUFA
• 4% PUFA.
  I cook with coconut oil and add some butter at the end, e.g. with my champigons cooked in the pan.

@GreekDemiGod said in Personal Log - Digestion, energy, vitality:

I've also took a B1, B6, B12 complex for a month. It improved some neurological symptoms that I've had.

You lack B2. Mainly. You could have neuro-problems if you don't care. Interaction.
B2 serves as prebiotic too.
Riboflavin and high thiamin
Does thiamine deplete riboflavin?
Klopp, Abels, and Rhoads found a transitory increase in riboflavin excretion in men treated with large doses of thiamine. Pro- longed administration of thiamine, however, failed to produce any clinical evidence of riboflavin deficiency.
Source: ScienceDirect.com
https://price-pottenger.org/pdfs/LF009_2.pdf (See & “Effect of Overloading with B”).
=> Mostlylurking has seen side effects when taking high dose Thiamin (B1) without supplementing riboflavin (B2). Not necessarily every day. Marked temporary increase of riboflavin excretion was not observed by all subjects (period not above 8 days).
Note: Besides B1, energy is enhanced by B2 (20%) and B3 (80%) (source: RP).