@thyroidchor27 said in Iodine as a game changer:
Iodine works well in the winter for boosting thermogenesis but I think in the summer its not really needed.
what about the other parameters?
If you feel / perceive cold hands or feet only in the winter, there are probably other symptoms of low metabolism you're accustomed and therefore think it's normal, or at least you manage with ... Until when !?
And it's not because you don't perceive it yet (under the radar), there aren't any low-grade problems ...
https://www.news-medical.net/news/20240321/Exploring-the-role-of-iodine-in-obesity-diabetes-and-other-metabolic-conditions.aspx
=> The correlation between iodine and metabolism: a review.
Excerpt
Mechanisms underlying the metabolic effects of iodine
Iodine exerts antioxidative, antimicrobial, immunomodulatory, and molecular regulatory effects. Iodine alters the proportion of pathogenic and beneficial bacteria to restore the gut microbiome and reduce insulin resistance, obesity, and metabolic syndrome parameters.
Iodine also reduces inflammation by lowering oxidative and endoplasmic reticulum stress caused by free radicals such as reactive oxygen species (ROS).
Iodine acts on the Kelch-like ECH-associated protein 1-NF-E2-related factor 2 (KEAP1-NRF2) pathway to enhance the activities of antioxidant enzymes such as superoxide dismutase (SOD), catalase (Cat), and glutathione peroxidase (GSH-Px).
In addition, iodine alters inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX2) levels, regulating mitogen-activated protein kinase (MAPK) and nuclear factor kappa B (NF-κB) pathways to reduce chronic inflammation and improve metabolic health.
The mineral acts on type 2 deiodinase (D2) receptors that convert T4 to biologically active T3 to improve weight management and adaptive thermogenesis.
Iodine also interacts with peroxisome proliferator-activated receptor-γ (PPARγ) receptors to enhance adipocyte differentiation, fatty acid uptake, and glucose metabolism ...
Source: The correlation between iodine and metabolism: a review.
2024 | https://doi.org/10.3389/fnut.2024.1346452
