Posts made by Jakeandpace

@sushi_is_cringe

Taking it everyday could be a problem, I think it’s to do with acetylcholine, you may develop dependency. I’m not too sure but after about a week of pouches I’m feeling the acetylcholine effects. My thoughts are that it’s probably best to do periodically to inhibit 5 - alpha reductase and boost dopamine but everyday I’m feeling like it’s detrimental overall. Caffeine is a better ‘crutch’ if that’s how you look at it. Caffeine is better for long term I’d say and I’d keep nicotine to something that’s like every couple days weeks or months if at all.

But I’ll say this, the initial dopaminergic effects I got are now feeling less and less ‘good’. I’m gonna take a few days off and see if I notice change when trying again in a few days.

If you’ve ever taken shilajit you’d know the strong acetylcholine effects that has, I’m able to tell when something has that effect. Taking nicotine for the past week has shown me that after a few days of use, the acetylcholine effect is prominent, and starts to become deteimental. Coffee, I don’t get this.

Just to bring this thread back.

Ive been experimenting with nicotine as I did in the summer. Summer I was using nicotine gum which I believe is synthetically derived and noticed slight cognitive enhancement in terms of dopamine but felt too much like acetylcholine. I recently started trying nicotine pouches recently at 6mg and noticed the cognitive effects are much better with the pouches than the gum oddly, but when searching a little I found This post on X.
Anyway I was doing these pouches and felt way too much of a buzz and adrenaline and a massive dump of dopamine which was the only part I enjoyed. Even when keeping the pouch in for shorter periods of time like 1-2 minutes I’d still get a bad reaction.

Definite benefits were decrease in estrogen and occasional increase in appetite, less abdominal fat. Better quality nails, increased dopamine.
Detriment was the adrenaline reaction and poor skin quality almost immediately after the hit but often then next day my skin would appear better than it had before which I liked. I also feel it’s harder to concentrate on tasks when I take too much.

Today I only put in the pouch for about 30s, almost no adrenaline reaction and felt much more relaxing. 6mg is definitely too much and not sustainable, it feels like over 3 espresso shots. If I can find less than 6 and preferably less than 3 I’d be happy.

It’s one of those drugs that people hear the benefits from and think more won’t harm them when infact it will.

I should also add I don’t feel the need to increase my dose of nicotine like other people say, honestly I don’t know how they feel the want more, I always feel like I want less and cravings are not as bad as people say, a little hit is all you need to quench them.

Less is more in the case of nicotine and probably also caffeine for that matter.

I also like this thread on RPF… nicotine through a peat prism

Looking at comments from a lot of YouTube videos etc it seems most people feel >3mg is too much and start seeing bad effects in terms of cognition and physical performance. But people think quitting cold turkey is the solution (similar to caffeine) while they ignore any sort of benefits the substance might have had, such is the problem with human nature. A moderation approach is best considered in this case as is with caffeine.

If others could share their experience that would be nice

Been away from the forum for a while, came back to see what’s happening. I haven’t been on the forum because it is really bad for my mental health. My social life and life in general takes a backseat to health.

Health is like a wild goose chase sometimes and because of that it in my opinion it can actually be healthier to take a look at your life and its direction than fix a problem that needs not be fixed. I think a lot of people delude themselves into a lack of Health and vitality (although not all).

Pursuing avenues that you want to explore in a creative way is much more healthy than “trying” to fix a problem related to your health sometimes and I think activated learned helplessness especially when trying solutions that don’t seem to work.

Taking the avenue that nothing needs to be fixed within your body is the first step and Ray spoke of this when taking about cancer treatment and how doctors feel the need to hack away at the body to remove the cancer.

Recently I’ve been thinking of Danny and Ray talk about people who have a purpose and direction in life through meaningful work. Danny points out that Ray (and himself I’m assuming) always seem to note that these people have the most vitality, look the youngest and have that youthful energy. I myself have noticed this.

Ray also said that when people tend to forget (or stop obsessing) about health they tend to be a lot healthier at that point.

The stress of obsessing over health (I emphasise the obsessing part) is probably worse than living life eating similarly to others who are not.

Another point is the point of the conscious mind. Ray said that he likes to take days (it might have been a week) where he doesn’t like to do much speaking or reading or writing, only focussing on the visual and I think this is related to activating the conscious mind. When you’re constantly being bombarded by language and information on forums your concious mind is also being activated, leaving little room for the subconscious to do the processing, I’ve noticed that some days I might take a break from talking or listening to music so much and all of a sudden I’m more fluent in both instruments and language. (This may be related to serotonin systems)

Brute de force speaks of the subconscious a lot if you know of him.

I wear glasses, I’ve noticed when taking them off and focusing on what I see for extended periods of time my vision gets better, slowly but surely. I’m more direct in my speech, I want to progress my life.

This is all to say that these forums may be a place meant for infrequent use and not to be checked daily. If you are serious about cultivating knowledge you’ll abandon the wild goose chase and allow the subconscious to do its processing, let the conscious mind rest while you recharge for the next conquest.

And this may be a step in the right direction showing that people are living and not ruminating.

Thanks for reading my monologue, as I say I don’t check the forum much anymore but be sure to leave your thoughts if you think I’m talking absolute rubbish or not I’d love to hear it.

@CrumblingCookie

Great thanks. Been meaning to try b6. Really mapping out all the Bs and their effects on me at this point

Does anyone know why when I take b12 (hydroxycobalamin) I feel slightly strange. It makes me feel good and strange at the same time.

Somehow it gives me a sharper jaw and makes my face sit in a more natural position to where I naturally mew however I can’t concentrate quite as well as I’d like and noticed some hair thinning and possible skin issues.

I’ve heard people talk about overmethylation. Is this something that can occur with hydroxycobalamin?

I had similar effects with folic acid but that made me even more mentally dull which I put down to it depleting b12 but I’m not so sure anymore. Also pantothenic acid thinned my hair. The only b that seemed to ever thicken it was b3 Niacinamide which also would give me bad blood sugar reactions if I wasn’t meticulous about dosing and timing.

Some good resources would be helpful. I suspected I was deficient only because I got positive reactions when supplementing like my nail moons coming back on my thumbs and those mentioned above as well as slight improvements in other areas. Thank you

@gg12

Been there, Mike Fave has some good content about controlling blood sugar as well as Chris master John and their both peat influenced. Also I’d go to the doctor if you’re seriously concerned.

@Corngold

Combats most of the inflammatory effects. Read this article by the man himself

@Corngold

If you’re talking about garlic possibly yes it might help with absorption of B1.

@dapose said in B complex:

Do you think high Biotin is going to through things out of whack? Sometimes I take 5mg b7 in case I have some mitochondria not working properly. ( I definitely have some damaged Mito’s!)
Peace!

I think biotin can cause problems if you’re not careful. Always be paying attention to your bodies reaction

https://youtu.be/uiEf9TydOQA?si=q_rzGP5CkLdgC0NS

@Corngold said in B complex:

@Jakeandpace

No. I've heard people say B12 or B6, or B complex can really help, and this was years ago, but I've never taken vitamins or B complex.

Is allithiamine in garlic not the same thing as thiamine? I eat lots of garlic but not sure if the B vitamins are very high in it.
I want to get vitamins only through food. It appears to me that most manufactured vitamins and supplements are tainted or poor quality. I understand there are arguments for trying to boost these vitamins temporarily. I'm also thinking I could be deficient in B vitamins because I don't eat as much fruit / citrus as I could.

Yea allthiamine is the fat soluble version of thiamine

Anyone take a b complex or have any good ones that they have noticed benefit from? In theory it seems like a good idea but like I’m not so sure it is. Just some anecdotes would be fine

@SpaceManJim

It's behind a paywall on his substack but I will share a short quote on it and hopefully I don't get banned from it for sharing.

"This is consistent with my hypothesis that B6 neuropathy is due to increasing transamination, with bottlenecks in CoA-requiring pathways leading to CoA sequestration, which can be aggravated by increasing the substrates that enter the bottlenecked pathway, relieved by cofactors that lead to the release of CoA, and relieved by adding B5 to help make new CoA."

That's his claim. He says in his own self experimentation he used P5P and this caused tingling extremities but also better dreams which he liked. He included zinc and this made things worse (but also better as his dreams were better) and concluded it was a bottleneck in energy metabolism. He included b5 and at varying doses and it solved his problem by the sounds of it.

"I have stayed on 75 mg of B6 and 500 milligrams of B5 for months because it is helping my sleep."

of course if you read the full article he provides in depth explanation for this. I really like his ideas on the bottlenecks in energy metabolism as I experienced similar things to him taking biotin in excess.

@Milk-Destroyer

Not for me. Considering the niacin is in the form of Niacinamide it wouldn’t make sense for it to be that so probably something else in it.

I’m making a more general enquiry I suppose about b vitamins and their effects (sometimes negative when in excess)

Edit* sorry I just saw the rest of the post, it could have been the citric acid your right. Glad your psoriasis cleared. Do you drink any form of caffeine or take any supplements as of now?

Anyone know why I get odd symptoms from energy red bull and not coffee? I think it must be the b vitamins, they make me feel uneasy whereas coffee does not. This happens even if I take the red bull with food. It does however definetly give a massive boost in dopamine feeling which I think is from the b6 and a reduction in acne with I think is from the pantothenic acid.

I think it’s causing my blood sugar to spike and then drop dramatically, it might be the Niacinamide. I just took a b complex and had a similar reaction. Not sure the b12 is too helpful but I suspect it is probably either a net positive or neutral because I think I was deficient.

Coffee causes an increase in acne but less oily skin. Red bull results in less acne but more oily skin noticeable on my hands???

I think it’s causing me blood sugar issues almost like diabetes, I get blurry vision in the mornings which is reduced to almost none from coffee drinking compared to energy drinks.

Really enjoyed the benefits of energy drinks but the downsides outweigh them in my opinion so I’m probably gonna quit. I may try the b complex with food and see if it makes a difference. I’ve experimented with Niacinamide, thiamine, riboflavin, pantothenic acid and biotin in isolation and Niacinamide and biotin seem to cause the blood sugar problems and maybe even pantothenic acid. A more tailored approach may be necessary, or maybe I was lacking thiamin and riboflavin to balance the other B’s in redbull.
Was gonna post on my log thread but this is my thread as well and I think it relates so here it is.

For now, drink coffee, have fun and don’t get to attached to ideology of nutrition. It’s all a big balancing game, you don’t want to fuck your body up at your age. Keep reading and do minimal experimentation, if something isn’t working stop doing it.

Only advice is eat more (try make it whole foods, this is important), drink some coffee, do some exercise that isn’t too exhaustive and have fun. Please do not stress too much about your body at this age, that would be the most unhealthy thing to do.

I like Chris master John’s explanation for b6 toxicity.

I found it quit dopaminergic the first time

@GreekDemiGod If you bring an icepack for your balls the problem is avoidable. Still a problem nonetheless for those not doing so

I suspect like most things that it is healthy up to a certain point. As long as you don't bleed into fat metabolism when doing sauna it is probably very beneficial. I wouldn't use it as a substitute for moderate exercise though but rather an adjunct to it.

200g is probably excessive. Eat your broccoli but just don’t have too much.