Posts made by jamezb46

@RageAchilles

I don't think that the added DHEA would "do nothing" just because you're young. By that logic why wouldn't the pregnenalone also do nothing if you're not deficient?

Haidut's recommendation is not to exceed 15mg DHEA per day in 3 divided doses, and to take steroids with niacinamide to increase NAD+/NADH.

He has also posted that 2-3 mg of androsterone limited aromatase activity by 90%.

So, taking something in the range of 10-15mg pansterone + 1-2 mg androsterone per day as a male should be ideal if you want the maximum effect.

@hcwilliams You could try tribulus terrestris. It is known to decrease elevated prolactin, increase DHT levels and does not raise estrogen.

Perhaps also look into stronger dopamine agonists/serotonin antagonists such as the beta cabergolines or their derivatives such as lisuride, 9 me-bc, bromocriptine.

To get estrogen under control I think androsterone is a good option.

@sneedful

Please explain where in OP there is even a hint of this "idealism" you speak of.

I ended it by saying that I doubt its realistic to work, for example, for the manufacturer of Mildronate, which is Grindeks.

I'm about to start a MS program in statistics and am wondering which pharmaceutical companies have a bioenergetic perspective?

Ideally, I want to work for/alongside a pharma company/scientists who are at least open to the idea of using metabolic modulation to achieve health outcomes.

From my brief research, it seems that many of the best pharma companies who have this perspective are in eastern Europe. I don't know how realistic it is to work for them.

@yeyo12

Yes, I did a 6 week cycle of tbol. Waiting until some injuries heal before I go back on.

I don't think sarms are as safe or effective as the orals I mentioned. But if you have some research showing that they're safe and effective, I'd be open to seeing it. I'm just not aware that they do anything better than tbol/var/dbol already can. They were also mainly developed by modifying antiandrogens, with some exceptions. Some are mixed agonists/antagonists. I'm also not sure about liver health at effective doses.

@Cezar4911 said in Oral steroids. Tbol/Dbol/Var:

@Serotoninskeptic pin something instead of playing around with insignificant amounts of oral steroids that are still a burden to your liver

Reply

Here is what pinning something will do:

1. Unless a very short ester is used (ex. Propionate), it will take weeks to even feel an effect

2. You will be injecting foreign material into the muscle/subcutaneous space that is likely to contain seed oils and is guaranteed to contain preservatives (BA, BB)

3. You will be guaranteed to be shut down if you run the injectable cycle for a time frame that makes any sense (16-24 weeks), and the suppression will last months after your last shot. Only way to mitigate is by taking enclomiphene (a potentially harmful pharma drug) or a powerful AI like aromasin or arimadex which if not dosed correctly will result in horrible low estrogen sides.

4. You will more than likely experience gyno or hair loss or both if you run enough injectable gear to get a meaningful effect. Even at TRT doses of testosterone, 20-70% of men had gyno.

Here is what running reasonable (20-30 mg) of tbol/var/dbol per day will do:

1. Will not suppress LH, FSH, GnRH to a meaningful extent.

2. Can get you amazing gains in the 6 week time frame that studies show is the time during which 90% of muscle gain and strength is accrued because of AR downregulation, even when using injectable cycles.

3. Allows you to cycle off after 6 weeks, after which your T levels will be normal and you can decide if another 6 week cycle is in order.

4. Will not significantly increase liver enzymes (very small increases were found in studies, but that can likely be mitigated or even abolished with NAC, TUDCA, vitamin C)

5. Will not give you gyno or hair loss, 19/20 times.

@Insomniac No it's 1:1

@Insomniac

Ray thought that alot of the pregnenalone available as supplements was damaged in the production process. Apparently if you heat the P5 too high, estrogenic substances are generated. Ray thought that some of those were present in virutally all products available OTC.

That's why he likes the progesterone better.

@thyroidchor27

Not necessarily. At doses of about 10mg/day there was almost no shutdown.

Some other steroids such as tbol and dbol also have minimal shutdown at low doses. You could probably get away with running them at around 20 mg/day for 6 weeks and not have any shutdown. 6 weeks on, 2 weeks off. Then repeat.

That's roughly what the east german athletes did during the state planned doping.

@pannacottas

Well, remember for @haidut anabolic is really anti-catabolic.

So, P4 he considers to be anabolic because of its anti-cortisol properties.

I want to belive this, but I find it to be doubtful. If it is really correct that AAS work primiarily through anatagonism of GR, then why don't RU486 or Emodin or beta-lapochone or other cortisol blockers make people jacked? Maybe it is the "synergy" between anagonism of GR and agonism of AR that is the real key.

That is a line of thinking developed in some of Haidut's other threads on RP forum about, for example, combining progesterone and oxandrololne and the general outline of why the "dutchess coctail" is effective.

Yes I agree that this needs to be tried and replicated. From about an hour of looking over the Cortinon thread of RP forum, many users reported some issues with comparitvely quite low doses of Cortinon, in the range of 2-4 drops, which is only 6-12mg P4, which pails in comparison to the 120 mg countenanced above.

@pannacottas

He did reply (or at least someone at Idealabs)

I was assured that the presence of DHEA should mitigate and/or eliminate the libido decrease and penis numbness that some males report with P4 only.

As far as those two bodybuilders @haidut mentioned, they were injecting 100mg P4 and 10mg DHEA per day, which they claimed was superior to 50mg Test E per day and probably equivalent to 75 mg+ Test E per day.

They did not make any claims about oral administration with their product (dissolved in tocopherols) being comparable to the injections that the bodybuilders were doing, but I think we can read between the lines a bit and realize they do not want a lawsuit.

I'm currently in the process of going through the 20 page Cortinon thread on the RP forum. This could be very promising.

@onliest

Damn you never had a wet dream?

Back when I was in high school I would regularly get them. In fact, there was one night when I had 3 in one night maybe the succubus that caused that found you

@pannacottas

I'm going to try to dissolve testosterone powder in a 10% solution of the same Cliganic product. I'll start with a 5% solution and if that holds, then I guess I'll decide at that point to either go for it or not.

There are a number of factors at play. For one, I'm not sure if I was ripped off by PPL. They might have given me Test A or test P.

But, there should be a way to make this happen. IdeaLabs can make upwards of 4mg of steroids per drop in Cortinon, so we know it's possible. Maybe it's the SFA/OA that makes the difference.

The only thing I worry about is that if I want to run the testosterone in vitamin E at say 25 mg/day, I don't want to run into issues with toxicity of vitamin E, so getting a 10% solution is kind of important.

@Serotoninskeptic

Yes, it does taste like coconut. It sweet as well. I went on a walk about 60 mins after eating some. My hands were very warm, heartbeat was fast as well. Felt like I was kind of "cooking" from the inside, but in a good way.

@BioEclectic

Or use calcium carbonate powder

@Sugarnotsnow

Someone has to do it

@Sugarnotsnow

Yes, both DHT and Androsterone are AIs. From peoples experience in the Forum, androsterone is a fairly potent one.

@LetTheRedeemed

That is why I love my squid and eggs

@Sugarnotsnow

The P5 comes from a study @haidut posted on the RP forum.

I think anything that opposes estrogen either at the receptor or by inhibiting aromatase would work. Whether 6 keto p4 would work is anyone’s guess.

Why do you want to use DHT? Just use T + Androsterone.

I am in the process of making my own T in vitamin E at 10% concentration so stay tuned for the results. Plan is to take around 25 mg per day combined with androsterone as needed for estrogen management ( I doubt I’ll need this - I’m fairly lean and muscular) and possible with pansterone. I’ll post when I have some data to report back on from that experiment