@alfredoolivas and @hwisdom
Why you should give a try with WWB.
We’re not talking about a crisis drug stuff. Since ASA (acid acetyl-salicylic) has an impact on platelet aggregation (for sure) and a possible by-side effect on mucin (epithelial protection of the linen intestinal walls) (aggressive and disruptive), we should learn how to manage to minimize the contraindications’ from these molecules.
I’ll give the direction where we should look at, not in details now.
There is an impact of ASA on platelets, and thus blood fluidity. Possible interaction with liposoluble vitamins?
Useful links on ASA & WWB
*) Impact of HD aspirin on platelet aggregation curve
https://mirzoune-ciboulette.forumactif.org/t2143-english-corner-impact-of-hd-aspirin-on-platelet-aggregation-curve?highlight=platelet
*) English corner: Aspirin cuts the spark; vitamin K keeps the current steady.
https://mirzoune-ciboulette.forumactif.org/t2144-english-corner-aspirin-cuts-the-spark-vitamin-k-keeps-the-current-steady#30424
Prevention for SARS-cov-2.
Vitamin K does not trigger clotting, it only ensures that the clotting and anti-clotting systems work effectively. Vitamin K is an essential cofactor for the activation of several proteins.
How MK-4 aids in redox recovery
Does aspirin counteract GLA protein or osteocalcin?
HD Aspirin take permanently inhibits existing platelets; recovery depends on new platelet formation (≈ 10 days). Whatever the dosage is (81, 325 or > 500-1000 mg ASA).
Vit K enhances balance: Vit K is an essential cofactor for the activation of several proteins.
*) Aspirin & Salicin from White Willow Bark – A Natural Path to Mitochondrial Vitality?
https://mirzoune-ciboulette.forumactif.org/t2128-english-corner-aspirin-salicin-from-white-willow-bark-a-natural-path-to-mitochondrial-vitality
NB: I'll begin with this new post:
Salicin and WWB Talk with Gemini 3
https://mirzoune-ciboulette.forumactif.org/t2163-salicin-from-wwb-vs-aspirin#30570
Context
Once salicin from WWB is converted (via hydrolysis and oxidation) into salicylic acid, it can interact with cellular energy systems in a few notable ways; often on a more mildly way.
Uncoupling of Oxidative Phosphorylation (Mild effect and Adaptive).
Inhibition of Mitochondrial Stress Signaling (NF-κB, TNF-α).
Protection against Lipid Peroxidation.
Stimulation of Pyruvate Utilization (no direct data, mildly apply) DOI:10.1136/jcp.54.7.553
Downregulation of iNOS and NO Overload (it supports mitochondrial longevity and cleaner respiration).
Excerpt
Salicin is hydrolyzed into saligenin (salicyl alcohol) and d-glucose in the intestines, primarily by gut bacteria (or enzymes). Saligenin is then absorbed into the blood and transported to the liver, where it is oxidized to form salicylic acid, the active compound with anti-inflammatory and pain-relieving properties.
https://www.stanfordchem.com/salicin-vs-salicylic-acid-relationship-difference-uses.html
