Some interesting stuff on pentoxifylline
-" PTX completely restored bone mass, bone strength and bone mineral properties by an anabolic mechanism. PTX has the potential to become an oral osteogenic drug for the treatment of post-menopausal osteoporosis."
https://pubmed.ncbi.nlm.nih.gov/30858147/
https://doi.org/10.1016/j.biopha.2021.112399
https://pubmed.ncbi.nlm.nih.gov/21748765/
https://lowtoxinforum.com/threads/some-pentoxifylline-studies.10437/post-345653
https://www.reddit.com/r/Nootropics/comments/1k6l3u7/pentoxifylline_makes_me_intelligent_again/
https://pubmed.ncbi.nlm.nih.gov/10506631/
https://lowtoxinforum.com/threads/evaluation-of-the-effect-of-pentoxifylline-on-sleep-deprivation-induced-memory-impairment.10310/
https://lowtoxinforum.com/threads/chorionic-morphine-naltrexone-and-pentoxifylline-effect-on-hypophyso-gonadal-hormones-of-male-rats.10305/
https://www.reddit.com/r/LongHaulersRecovery/s/mh5AO1rOBA
Ray Peat:
"The use of nitric oxide for treating pulmonary
hypertension is deflecting interest from generally
safe substances, such as magnesium, oxybutyrate,
pentoxifylline, progesterone, DHEA, testosterone,
and thyroid hormone, and directing attention
away from the various factors that cause the
pulmonary hypertension of adults as well as
newborns. "
"Although caffeine, if it’s combined with hypoglycemia and stress, will increase lipolysis and free fatty acids, several of the methylxanthines, including caffeine, theophylline, and pentoxifylline, can protect against capillary leakage, probably by a variety of antiinflammatory actions, including inhibition of nitric oxide synthesis (Bereta, et al., 1994).”