Haidut mentioned:
PUFA and Endotoxin (LPS) Inhibit Vitamin D and Thyroid Transport / Activity
Polyunsaturated but not saturated fatty acids were able to decrease the binding of thyroxine to TBG (thyroxine-binding globulin).
Arachidonic but not palmitic acid decreased the binding of 25-hydroxyvitamin D3 (25-OHD3) to human DBP.
"...In non-thyroidal illness, however, high concentrations of FFA were probably responsible for most of the abnormal thyroxine-binding to TBG.”
FFA = Free fatty Acid.