@CharlieLover123 I think manifacturers have som type of process and rules on the mg dosing per pill. It's a bit of a hassle if you buy 100mg HCL and plan on taking 600mg+. HCL is the ''weakest'' of them all, but personally it makes me feel great. Benfotiamine and Sulbutiamine give more energy and require less dosage than HCL. I think its 300mg+ for Benfo and Sulbu and 50mg+ for TTFD. TTFD unlike any other crosses the blood-brain barrer and has more benefits on theory, but supplmenting,as some people said, requires more nutrients

Also consider the phosphate to calcium ratio Peatbot.com: The phosphate to calcium ratio is important because it plays a crucial role in various physiological processes and can impact health in several ways: Bone Health: Calcium and phosphate are essential components of bone. An appropriate balance between these two minerals is necessary for maintaining bone density and strength. An imbalance, such as excess phosphate relative to calcium, can lead to bone loss or decalcification, as phosphate can activate processes that remove calcium from bones. Soft Tissue Calcification: When there is an excess of phosphate, it can lead to the deposition of calcium phosphate crystals in soft tissues, such as blood vessels, which can contribute to conditions like arteriosclerosis. This is because phosphate can promote calcification in soft tissues, which is undesirable. Cellular Function: Phosphate ions in cell water can modify ion selectivity, affecting the uptake of other ions like sodium, calcium, and potassium. This can lead to changes in cell activation and depolarization, impacting cellular function and signaling. Mitochondrial Function: Increased phosphate levels can decrease mitochondrial energy production, leading to lipid peroxidation and activation of inflammatory processes. This can contribute to tissue atrophy, fibrosis, and cancer. Hormonal Regulation: Phosphate levels can influence the activity of hormones such as parathyroid hormone, which regulates calcium and phosphate metabolism. High phosphate levels can increase parathyroid hormone activity, leading to inflammatory diseases and bone loss. Dietary Considerations: The balance of dietary phosphate and calcium is important for overall health. Excessive dietary phosphate can promote organ growth and cancer, while a deficiency can lead to increased cellular uptake of phosphate, mimicking the effects of excess dietary phosphate. Overall, maintaining an appropriate phosphate to calcium ratio is crucial for preventing various health issues related to bone health, soft tissue calcification, cellular function, and hormonal regulation.

@Korven I just did a cycle of t3 and I too feel pretty horrible in general, much better off the meds. I say work on your metabolism through diet and lifestyle and leave the thyroid meds out unless you’re actually clinically hypo.

Progest-E from long natural health has arrived! My mom is excited to try it out.

@DavidPS I just put topical niacinamide on my nose with water and it smelled bad.

Just reporting back here that my first experience with micellized D3 did not go well. Was really hoping this would be the trick to getting D3. Unfortunately, I felt anxious and very off, then a typical malaise. I believe the anxiety was due to some hormonal change, to use a very unscientific description. The one thing different from most other supplements, especially fat-based D3, was that the heavy malaise did not last long at all, where it usually always does — days. When I get the courage, I'll try this again.

@wester130 No but I’ll check it out.

@Uroš Don't know what's the optimal but it makes sense taking it with food to slow the absorption to mimic the natural production and release. I just upped to 3 grains and I think the easiest way for me is to take the T3 three times a day with a bigger meal, with only the last meal also containing all of the T4. There's probably individual variance in what works best.

@Alomongerpete I think ray used a in ear thermometer

@pittybitty you don't experience dry skin at all?

Late update: Finally settled on this as it's closer to my region: https://myospots.com/products/natural-toothpaste-with-hydroxyapatite

@the_black_jew https://live-live.com/products/biocean-tonics-1000ml

Halogen lighting is a good choice. Let us know what your experiment reveals. [image: 1736875664998-c5419000-a8f5-4ef4-a1d2-38d23c3ac7c2-image.png]

There are many production methods. https://www.guanjiebio.com/news/how-many-plant-extracts-production-process-do-75963188.html

@Wamoti, below is the brand I have. It’s the one many of the old Ray Peat Forum members were using back in 2015 when we were experimenting with FOS. I’m not sure if they still carry it, but I got it from the pharmacy at Walmart: [image: 1735994725078-fbbec0a6-1065-409e-a11c-80a04d5c67f3-image-resized.jpeg]

@Serotoninskeptic incandescents r better imo

that sounds disgusting tbh. your kid's gonna throw it to the birds and go get an oh Henry from the vending machine.

@ilnyarienàfaire Do you have other health conditions? What is your TSH? Do you get sunlight/vit D? Do you lead a virtuous, meaningful life? Have you tried CBT/ do you have defense mechanisms for dealing with negative thoughts?

@TemetNosce Is there a reason why you aren't using Progest-E?