Hi
I’ve been inquiring about nattokinase and serrapeptase (or serrapeptidase) because I wanted 15 years ago (I’m 71 years old) to attack fibrin plaques. These are the only enzymes supposed to do this job. They are proteolysis, as said by Yerrag, but with a specifity:
these enzymes only target died / necrosis tissues, not the wealthy ones.
At least there are supposed to do so, because after a while – let’s say +/ 6 weeks – I felt I had to stop: sensitive throat. Nothing important but enough to say the job had been done. I said to myself: better stop here if you don’t want a counter-side effect. Not really rationale.
By the way, you need to get informed on what is able to protect membranes (in short: Vit E, K and beta-carotene). But not at the same time !! (Vit E and K1 have anti-aggregation anti-coagulation effects). Thus mind with blood pressure medications.
Moreover, don’t trust the advantages given by a labo or a seller. Only from a medical study.
Info on serrapeptase
http://mirzoune-ciboulette.forumactif.org/t1251-agents-naturels-pour-lutter-contre-le-biofilm-bacterien#13696 (in French; translator needed but with interesting links, in English)
What is Serrapeptase? How does Serrapeptase work?
Serrapeptase reduces pain and inflammation in three different ways:
Serrapeptase breaks down fibrin, which is a protein involved in blood fluidity and coagulation.
Serrapeptase reduces fluids associated with inflammation. This allows rapid drainage far from the inflammation site and leads to faster recovery times after an injury or surgery.
Finally, the Serrapeptase has the ability to partially relieve pain by blocking the release of bradykinin in damaged tissues. Bradykinine is a protein responsible for triggering a painful response.
Comment (Luc): OK but not so effective in reducing the inflammation. The mechanisms of action of Serrapeptase (SP), on the sites of the various inflammatory processes consist fundamentally in a reduction in exudative phenomena (swelling with effusion of liquid) and inhibition of the release of inflammatory mediators. Thus interesting as extra agent. A facilitator (That makes it easier to recover).
Biofilm and Serrapeptase
A proliferation of bacteria prevents the mucosa of the small intestine from absorbing vitamins and minerals. This situation can prevent the large intestine from absorbing fats and amino acids. When they are invaded by a bacterial film, the intestines cannot return the bile salts to the liver, and the excess cholesterol is not recycled (...)
Some examples of selected products are given, all with enteric coating (or equivalent).
Note: Serrapeptase is easier to find than nattokinase.
About nattokinase, a member of Chris Kresser’s forum has reported (Prioris, April 4, 2014 at 5:41 pm)
In the case of a patient, with a poor arterial profile, former smoker and overweight, Chris Kresser advised, in the event of narrowed coronary arteries whose blood circulation is 70 % blocked:
Use nattokinase. It is a natural clot buster. It works. I had severe peripheral artery disease and could hardly walk. Nattokinase took away all the symptoms within a month. Been well for last 10 years. There are no side effects and no worry about taking too much. It takes a couple months to remove most of the blockage. Doctor’s Best brand is brand I use.
Take 4000 FU, 3 times a day on empty stomach for first months and then use when waking and going to sleep. You could also take some serrapeptase with it. Maybe 40,000 IU.
Long term maintenance is 2000 FU in morning and/or night (before bed is best time to take it).
If you want to research it further, look up fibrinolytic enzymes. Also look up cholesterol myths.
My other advice (prioris speaking):
do not take aspirin while taking it.
do not take vitamin K2 since it is a coagulant while clearing blockage
do not take blood pressure medications because they can irreparably damage your health.