@A-Former-User said in How to lower Adrenaline:
I remember from the RP Forum that you're a huge fan of thiamine and convinced that thiamine deficiency is behind most people's problems. I'm not so sure about that. The list of symptoms of thiamine deficiency is basically every symptom under the sun, and I know that Ray Peat was never terribly convinced that thiamine was the be all and end all. I asked him about it once and he said it's most likely hypothyroidism. He advocated for dosages between 10-100 mg a day. There is a very long list of people who believed they had beri beri and started taking high dose thiamine and experienced nothing but misery and a host of new problems, which I know the thiamine cheerleaders simply call "the paradoxical reaction" (or something to do with methylation or not having the right co-factors etc), but it never went away and they had to give up. They're in a facebook group and it's depressing reading. Do me a favour mate and PLEASE don't spam every thread on this new forum with the beri beri guff!
I should just ignore you because you are being a first class jerk. But I've decided to respond instead.
#1: Ray Peat recommended thiamine quite a lot actually; he just never wrote a full article about it. Here are a few links for your consideration:
Thiamine mentioned in Ray Peat's written work
Vitamin B1 (thiamine) mentioned in Ray Peat's written work
Thiamine mentioned in Ray Peat's audio interviews
Vitamin B1 (thiamine) mentioned in Ray Peat's audio interviews
#2 This forum is named the Bioenergetic Forum for a reason.
https://www.nature.com/subjects/bioenergetics
"Bioenergetics is the branch of biochemistry that focuses on how cells transform energy, often by producing, storing or consuming adenosine triphosphate (ATP). Bioenergetic processes, such as cellular respiration or photosynthesis, are essential to most aspects of cellular metabolism, therefore to life itself."
Ray Peat focused a lot on the concept that if cellular energy is optimized then health follows.
It will probably come as a shock for you to learn that thiamine is required for cellular energy. Thiamine acts as a co-enzyme in several steps in the Krebs cycle which is how cellular energy (ATP) happens.
The importance of thiamine (vitamin B1) in humans