@Mulloch94
I have no idea how PTH would influence magnesium. It may but in away where magnesium would be indirectly affected in the sense where CCBs would have a systemic influence where all are affected.
I can speak to my personal observation. I regularly monitor my acid-base balance where I test the pH of both my urine and saliva.
Despite my high blood pressure, when I am not taking bp meds, I see more of a state of balance where my body is given free reign to adapt optimally as it area fit to a given pathological influence, which in my case involves a recurring unresolved state of low-grade infection and exposure to lead toxin. One aspect is in the way my body strives to achieve a state of acid base balance.
I don't feel any arthritic pains in my joints. I don't have a problem with my bladder holding on to urine. However, I wake up often to pee at night, which I associate with water being produced as a product of redox reactions where antioxidants neutralize spillover ROS, which comes to my immune system creating ROS to try overcoming pathogenic microbes and toxins. Still, I look for ways to resolve the infection and toxic state in order to resolve the root causes. While the root causes remain unresolved, my body is remarkable in adapting to this unresolved state. A symptom of this adaptation to the unresolved state is hypertension.
When taking the calcium channel blocker, I see lower bp but I also feel the price I have to pay for the appearance of health in the form of lower blood pressure.
My urine and saliva pH testing would show a marked departure from my state of acid-base balance. The CCB interfering with the calcium channel is expressed clearly when my urine and saliva pH testing reveals a constant imbalance in acid base regulation. Unlike when I am not taking CCB's, my body is always unable to catch up in ridding itself of excess acidity during rest, which occurs at night. So, I would urinate more frequently during both day and night, and I would be peeing in my pants (and feeling old and incontinent) even at times when my bladder is not even half-full. My knees and ankles would feel sore as well, which I suspect is the effect of uric acid precipitating on my joints.
If not for taking furosemide and spironolactone, both being diuretics, I would be developing edema at my ankles and my waistline would bloat from ascites developing.
I should stop now, as the side effects from taking bp medication (so far I have mentioned amlodipine, furosemide, and spironolactone) can have me go on endlessly.
And I am going off topic somehow, but I only want to bring home the point that interfering with the calcium channel has systemic effects. It just isn't worth it to take calcium channel blockers to appear normal bp-wise while ignoring the effects on other areas which our doctors trivialize and even consider coincidental.
I tried to find some authoritative sources on the effects of CCB's, but I have difficulty doing that. My research skills are not as good as that of you and @Amazoniac 's, and what I find are mainly topics that are peripheral and not central to the issue. I suspect it is so because such research or inquiries are frowned upon by the establishment. Unfortunately, I have been spoiled by Peat doing the legwork for me, and I wished he had expounded in his writings on CCB's.
One thing one of his last newsletters mentioned was that when the body is doing osteoclastic activity, it cannot at the same time do osteoblastic activity. Osteoclasts break down bone to provide the body with calcium when the PTH signal is high. In this situation, no osteoblastic activity can be done. Bone building requires CO2, so it goes that during this time mitochondrial respiration is halted to give way to other metabolic pathways. These other metabolic pathways often involve producing acids, such as lactic acids and keto acids.
When the metabolic pathway becomes anything other than mitochondrial respiration, the body becomes acidic more and more. And all sorts of imbalances and pathology result, especially when it becomes a permanent and chronic feature.
Even when one has adequate mineral stores in the body such as potassium and magnesium, they are not utilized in the way they should be, because the general condition that permeates, as determined by an acid-base imbalance,
overrules the salutary nature of these substances.