Thought I should post a brief update since this thread has gotten some more attention lately: The symptoms I was dealing with have greatly improved with some diet and lifestyle changes. I've reduced my zinc supplementation to a more standard 15mg a day, but I still feel 120mg/day was beneficial as a short-term loading dose. I do get plenty of copper and manganese in my diet from regular shellfish consumption, and I've started using molasses as well. If anyone is interested, the current stack I'm running is a standard B-complex, 300mg thiamine HCL, 8000IU vitamin D, Thorne's vitamin K formula, 15mg zinc citrate, and T3/T4, progesterone, pregnenolone, and DHEA rarely as needed