Subcategories

• Literature Review

  Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.
  641 Topics

  4k Posts

  A

  Abstract Alcoholic beverages produced by fermentation (e.g., beer and wine) are powerful stimulants of gastric acid output and gastrin release in humans. The aim of this study was to separate and specify the gastric acid stimulatory ingredients in alcoholic beverages produced by fermentation. Yeast-fermented glucose was used as a simple model of fermented alcoholic beverages; it was stepwise separated by different methods of liquid chromatography, and each separated solution was tested in human volunteers for its stimulatory action on gastric acid output and gastrin release. Five substances were detected by high-performance liquid chromatography and were analyzed by mass spectrometry and 1H-13C nuclear magnetic resonance spectroscopy. At the end of the separation process of the five identified substances, only the two dicarboxylic acids, maleic acid and succinic acid, had a significant (P < 0.05) stimulatory action on gastric acid output (76% and 70% of fermented glucose, respectively), but not on gastrin release. When given together, they increased gastric acid output by 100% of fermented glucose and by 95% of maximal acid output. We therefore conclude that maleic acid and succinic acid are the powerful stimulants of gastric acid output in fermented glucose and alcoholic beverages produced by fermentation, and that gastrin is not their mediator of action. ... When tested separately, oxalic acid, acetic acid, and L(+)-lactic acid had no stimulatory effect on gastric acid output. Maleic acid and succinic acid, however, significantly increased gastric acid output by 76% and 70%, respectively, of fermented glucose (Figs. 2 and 4). When given together in the concentrations present in beer, maleic acid and succinic acid significantly increased gastric acid output by 95% of MAO(maximal acid output) and 100% of fermented glucose. J. Clin. Invest. 103:707–713 (1999) https://pmc.ncbi.nlm.nih.gov/articles/PMC408116/
• Ray Peat Resources

  Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.
  62 Topics

  702 Posts

  C

  Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
• Not Medical Advice

  Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.
  1k Topics

  10k Posts

  P

  @polba you are welcome It takes time and being consistent But you will feel much better and symptom free Just easy to digest stuff Nothing that irritates your digestion u
• Products

  From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.
  385 Topics

  4k Posts

  E

  @user73636 if the study you mention is indeed true, it's not clear if it would still be valid for Pyrucet specifically because it includes the ethyl pyruvate to replenish the PDH that the EA would reportedly inhibit.
• The Kitchen

  Recipes, food, meal prep, brands. Discuss them all here.
  236 Topics

  2k Posts

  L

  A single portion (240ml) of UHT milk is like welcoming just one tourist in Venice. Not overcrowded. You get the value of the nutrient, but the load is manageable, allowing your small metabolism to process and keep the not-well-fit amino-acid under control (not used). If someone overloads himself with one gallon at a time, twice a day, it won't make you "more nourished." It will make you tired and leave your body feeling crowded and overworked by the demands of processing it all, when something is not well manufactured / recognized. Management is all. Even if you don’t perceive it. And don’t tell you know someone who … Finally: Think, perceive and act, as someone not far from here would say “If UHT milk is the only option, a single portion (~240 ml or half a gallon) is manageable. Think of it like one extra car on a quiet road — the system absorbs it without stress. Moderation keeps the metabolism in control. A moderate amount keeps the metabolism in control of what it can process and discard.
• The Gym

  Discussing pistol squats, concentric exercise, resting, and other forms of strength training.
  86 Topics

  1k Posts

  R

  @LunaticRed what @alfredoolivas said along with inhibiting cortisol, positive androgenic effects like increased strength, bone growth, anti-anxiolytic, controls blood sugar, controls inflammation from endotoxin. The list goes on. In reality, it is the TRUE male hormone.